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Medical News | Medical Articles | Genetics - Jan 9, 2019 Edition

	January 9, 2019
	Genetics
	The latest Genetics news from News Medical

Genetically diverse mouse models improves usability for precision medicine for Alzheimer's

Incorporating genetic diversity into a mouse model of Alzheimer's disease resulted in greater overlap with the genetic, molecular and clinical features of this pervasive human disease, according to a study funded by the National Institute on Aging, part of the National Institutes of Health.

			Research reveals factors at play in genetic incompatibility of different species Most evolutionary biologists distinguish one species from another based on reproductivity: members of different species either won't or can't mate with one another, or, if they do, the resulting offspring are often sterile, unviable, or suffer some other sort of reduced fitness.

			Extensive genetic tests do not cause undue worry for women with breast cancer As genetic testing for breast cancer has become more complex, evaluating a panel of multiple genes, it introduces more uncertainty about the results. But a new study finds that newer, more extensive tests are not causing patients to worry more about their cancer risk.

	Researchers identify genetic risk factor for atypical heart attack in women New research published by teams from Leicester, UK and Paris, France in collaboration with international partners from the US and Australia, has found a common genetic factor that confers a significant risk of atypical heart attacks in women.

	Rockefeller scientists uncover genetic mutation responsible for tuberculosis vulnerability If you live in the United States, you are unlikely to come into contact with the microbe that causes tuberculosis. Your odds of encountering the microbe are so low, in fact, that risk factors for the disease can easily go unnoticed: If you happened to carry a gene that predisposed you to tuberculosis, you likely wouldn't know.

	Researchers reveal cause of possible genetic problems in mitochondria A group of researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine has revealed the importance of eliminating any excess of defective products that might have accumulated in the mitochondria, as its presence generates mitochondrial instability and information loss on the mitochondrial genome.

	Study provides new insights into how genes are activated In a study in Nature, researchers at Karolinska Institutet present a new method for analyzing how instructions in the genome control how our genes are activated in individual cells.

	Researchers identify genes that drive male-female brain differences, trigger initiation of puberty Researchers have identified a group of genes that induces differences in the developing brains of male and female roundworms and triggers the initiation of puberty, a genetic pathway that may have the same function in controlling the timing of sual maturation in humans.

	Scientists highlight lack of diversity in genomic studies A growing number of genomic studies have generated important discoveries regarding human health and behavior, but new research from the University of Oxford suggests that scientific advancement is limited by a lack of diversity.