Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury | Science

Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury | Science

Thursday, December 6, 2018

Immune Cells “Trained” by Skin Microbiome Promote Rapid Response to Wounds

In a new report out today in Science, NIAID researchers describe how recognition of the skin microbiome helps immune cells in those tissues quickly repair tissue when the skin is injured. The findings further researchers’ understanding of the importance of these commensal microbes in health and immunity.

Commensal-specific T cell plasticity promotes rapid tissue adaptation to injury

1. Oliver J. Harrison1, 
2. Jonathan L. Linehan1,*, 
3. Han-Yu Shih2, 
4. Nicolas Bouladoux1, 
5. Seong-Ji Han1, 
6. Margery Smelkinson3, 
7. Shurjo K. Sen4, 
8. Allyson L. Byrd1,*, 
9. Michel Enamorado1, 
10. Chen Yao2, 
11. Samira Tamoutounour1, 
12. Francois Van Laethem5,†, 
13. Charlotte Hurabielle1,6, 
14. Nicholas Collins1, 
15. Andrea Paun7, 
16. Rosalba Salcedo8, 
17. John J. O’Shea2, 
18. Yasmine Belkaid1,‡

 See all authors and affiliations

Science  06 Dec 2018:
eaat6280
DOI: 10.1126/science.aat6280