domingo, 1 de mayo de 2016

NIOSH Research Rounds - April, 2016

NIOSH Research Rounds - April, 2016

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In This Issue



Volume 1, Number 10 (April 2016)

Job Stress

Job stress refers to the harmful physical and emotional responses that occur when the requirements of the job do not match the capabilities, resources, or needs of the worker. Job stress can lead to poor health and even injury.

The concept of job stress is often confused with challenge, but these concepts are not the same. Challenge is an important ingredient for healthy and productive work. It energizes us psychologically and physically, and it motivates us to learn new skills and master our jobs. When we face a challenge and handle it well, we feel relaxed and satisfied. The importance of challenge in our work lives is probably what people are referring to colloquially when they say, "a little bit of stress is good for you.” In reality, while challenge can be good for personal growth, stress is never good by any measure. One form of stress under investigation at the National Institute for Occupational Safety and Health (NIOSH) is job strain, which occurs when high job demands combine with low job control. As part of its commitment

Job Control in Many Occupations Linked to Decreased Risk of High Blood Pressure

Does your job provide a variety of tasks? Do you have the opportunity to develop your own special abilities? Are you able to make work-related decisions on your own? Do you have the freedom to decide how you do your work? If so, you may have a job that gives you a high level of control. This kind of control correlates with a decreased risk of high blood pressure in many occupations, according to a study by NIOSH with university partners.

In this study, workers with the highest level of job control were less likely to have high blood pressure than were workers with the lowest level of job control. This association occurred in many different job areas, including management/professional, sales/office, and production. However, in the case of healthcare support workers (for example, home health aides, nursing assistants, dental assistants, medical transcriptionists, pharmacy aides, and phlebotomists), the pattern reversed; high job control correlated with a greater risk for high blood pressure. Although overall a greater proportion of men than women had high blood pressure, more women in healthcare support and two blue-collar job areas (production; and installation, repair and maintenance) had high blood pressure. The results were similar across racial/ethnic groups.

Nightshift Work and Job Strain Associated with Weight Gain

When her children started school, Susan* felt fortunate to land a job as a nightshift nurse, a job that would enable her to be there for her children when they came home in the afternoon. Even though the work was demanding, a year into her new job she felt confident about understanding her job duties and mastering necessary skills. However, what she did not understand was why her new work uniform no longer fit comfortably, and she was concerned about the health effects of gaining weight.

Workers who work outside of regular daytime schedules—night shift workers—may experience greater levels of job strain. Few studies, however, have examined shift work and job strain together in connection with weight gain. Now a study in progress by NIOSH investigators and their university partners is looking at the joint effect of shift work and job strain on women’s weight gain over 4 years. The investigators plan to control for other factors that could affect weight gain, including age, race and ethnicity, pregnancy history, job types, change in family situations, and health behavior.

Job Strain Linked to Greater Weight Gain among Already Overweight Women

Job strain correlated with greater weight gain among already overweight women than among women who weighed less initially, a study by NIOSH and university partners has found. These findings underscore the importance of identifying and addressing occupational factors to prevent obesity, rather than focusing on behavioral or individual factors in isolation. This approach is consistent with NIOSH recommendations in its Total Worker Health® Program.

Although obesity is a recognized risk factor for a host of serious diseases—including heart disease, cancer, stroke, diabetes, and kidney disease—its relationship to job strain has remained unclear. Previous NIOSH-supported research found that women who reported five job stressors on a regular basis had a four-fold greater risk of obesity than women who reported no job stressors. In the current study, investigators specifically examined the relationship between job strain and change in the height-to-weight measurement known as body-mass index (BMI). They found that women reporting high job strain at least once had a greater increase in BMI over 4 years than did women reporting no job strain. Voluntary study participants included 52,656 adults in the ongoing Nurses’ Health Study II of health and behavior among nurses and student nurses in the United States and Canada. Participants’ average age was 38.5 years, and most were white.

Relationship between Job Strain and Stress Hormone Explored

Increasingly, medical research links stress, including work-related forms such as job strain, to a range of serious health effects, such as obesity, diabetes, certain types of cancers, and heart disease. One of the main hormones released in response to stress is cortisol. Occupational health researchers study this hormone as a biomarker to measure the possible health effects of job strain and, ultimately, to develop better interventions to prevent job strain. Previous research, however, found inconsistent results in the relationship between cortisol and job strain. One reason for this inconsistency may have been failure of those studies to account for day-to-day variability in cortisol.

Investigators at NIOSH, along with university partners, designed a new study to account for this variability and to address other possible limitations in earlier investigations comparing daily cortisol levels with high-strain versus low-strain jobs. Accounting for day-to-day variability is important because an individual’s cortisol levels are highly variable within and between days, the investigators said. Cortisol levels typically rise sharply at the time of waking and then decline throughout the day, so the investigators compared hormone levels in salivary samples from voluntary participants at six different times daily for 3 days. In addition to comparing overall cortisol profiles, the investigators compared two commonly used cortisol summary measures. The first measure is the “cortisol awakening response,” which is the increase in cortisol levels from awakening to 30 minutes later that likely shows the body’s ability to respond to stress. The second measure is the total cortisol released from awakening to 16 hours later, known as the “area under the cortisol curve.” A growing body of data suggests that chronic stress and associated health conditions may impair the release of cortisol, what the investigators call a “blunted cortisol diurnal profile.”

Next Steps

Identifying how job stress contributes to early signs of disease will provide critical information for effective prevention. In a first step in this direction, NIOSH and university partners studied how occupational characteristics predict blood vessel changes that signify early heart disease. Due to methodological difficulties, investigators were not able to identify a clear link between job characteristics and these signs of early heart disease. Nevertheless, this study clarified the importance of more detailed and accurate assessment of occupational characteristics and exposure history.

For the study, investigators analyzed data from MESA. Using noninvasive ultrasound imaging, MESA investigators measured the lining of the main artery in the neck—the carotid artery—and the amount of plaque, or fatty substances, built up within the artery. Both carotid thickening and plaque formation are early signs of developing heart disease. Voluntary study participants included 3,109 adults from six communities in North Carolina, New York, Maryland, Minnesota, Illinois, and California. Their average age was 60 years; half were women, and all were free of heart disease when the study began. Study participants underwent ultrasound imaging of the carotid artery once at the beginning of the study and at least once more over the following 9 years. To obtain participants’ occupational information, investigators asked their current or pre-retirement job title and retrieved job characteristics from the U.S. Department of Labor database (Occupational Resource Network, O*NET) that describes each job.

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