viernes, 7 de agosto de 2015

Final Research Plan: Genital Herpes: Screening - US Preventive Services Task Force

Final Research Plan: Genital Herpes: Screening - US Preventive Services Task Force



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The U.S. Preventive Services Task Force posted today a final research plan on serologic screening for genital herpes. The draft research plan for this topic was posted for public comment from April 30 to May 27, 2015. The Task Force reviewed all of the comments that were submitted and took them into consideration as it finalized the research plan. To view the final research plan, please go to http://www.uspreventiveservicestaskforce.org/Page/Document/final-research-plan/genital-herpes-screening1.


The figure is an analytic framework that depicts the seven key questions described in the research plan. In general, it illustrates the overarching questions of whether serologic screening in asymptomatic sexually active adults, adolescents, and pregnant women with no clinical history of genital herpes leads to improved health outcomes or potential harms. It also illustrates the intermediate steps and key questions about the accuracy of serologic screening tests for early detection of genital herpes. Finally, it illustrates whether treatment of genital herpes leads to improved health outcomes or potential harms.
*Studies that screen using an HSV-2 serologic test alone or a “paired” (HSV-1 and HSV-2) serologic test will be included if they meet other eligibility criteria; however, only the accuracy of test characteristics related to HSV-2 serological tests will be evaluated.
**KQ 7 will only be addressed if there is insufficient literature for KQs 1 and 5 but sufficient literature for KQ 4.
Abbreviations: KQ=key question; HSV=herpes simplex virus.

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