BioMed Central | The Open Access Publisher

BioMed Central | The Open Access Publisher

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  HCV in HIV-positive men who have sex with men

  Molecular characterization of HCV in HIV-positive men who have sex with men demonstrated that the origin of HCV in this population was diverse and not directly linked with local injection drug users.

  Virology Journal 2015, 12:120
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  Ovarian cancer landscape

  Exome sequencing of mucinous ovarian carcinoma tumors reveals multiple mutational targets, suggesting tumors arise through many routes, and shows  this group of tumors is distinct from other subtypes.

  Genome Medicine 2015, 7:87
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  BioWardrobe

  A platform allowing users to store, visualize and analyze epigenomics and transcriptomics data using a biologist-friendly web interface, without the need for programming expertise.

  Genome Biology 2015, 16:158
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  Are RAS-positive thyroid nodules malignant?

  In patients with thyroid nodules, RAS oncogene mutations are associated with malignancy risk, but the majority of RAS-positive cancers are low-risk, suggesting that RAS expression should not be used alone to guide clinical decision-making.

  BMC Medicine 2015, 13:184
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  Bipartite structure of the inactive mouse X chromosome

  The active and inactive X chromosomes have different three dimensional structures, with the inactive X being similar in mouse and human

  Genome Biology 2015, 16:152
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  Alcohol and breast cancer risk

  A study of 25–35-year-old women finds a link between alcohol consumption and increased mammographic density and estrogen levels.

  Breast Cancer Research 2015, 17:103
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  Epigenetic changes associated with PDR

  Altered blood DNA methylation patterns occur in type 1 diabetes (T1D) patients with proliferative diabetic retinopathy (PDR) compared with those with T1D and no retinopathy, suggesting that epigenetic changes may predict PDR development.

  BMC Medicine 2015, 13:182
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  OrthoFinder

  Solving fundamental biases in whole genome comparisons dramatically improves accuracy of orthogroup inference

  Genome Biology 2015, 16:157
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  Does exposure predict malaria episodes?

  Modeling exposure fails to account for all excess malaria episodes in children living in P. falciparum endemic areas, suggesting additional factors may contribute to unexpected episodes and urging the need for a framework to identify those at risk.

  BMC Medicine 2015, 13:183
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  Metastasis or second primary?

  Whole genome sequencing was used to differentiate metastatic from second primary tumors in contralateral breast cancer patients: a distinction with clinical implications for treatment and prognosis.

  Breast Cancer Research 2015, 17:102