VSV-based Nipah Virus Vaccine Fully Protects African Green Monkeys

VSV-based Nipah Virus Vaccine Fully Protects African Green Monkeys

VSV-based Nipah Virus Vaccine Fully Protects African Green Monkeys

A recent NIAID study showed that a vaccine using the same platform being tested in volunteers in West Africa against Ebola virus also protects African green monkeys exposed to Nipah virus a month after a single vaccination. The vaccine uses vesicular stomatitis virus (VSV) as a vehicle to transport immune-generating components of various pathogens – in this study Nipah virus – into a host to generate an immune response. VSV, an animal virus that primarily affects cattle, has been successfully tested as an experimental vaccine platform against several viruses.