Celiac Disease: Genomic Insights - April 29, 2015

Genomics|Features|Celiac

Celiac Disease

Celiac Disease: Genomic Insights - April 29, 2015

Common polygenic variation in coeliac disease and confirmation of ZNF335 and NIFA as disease susceptibility loci 
Coleman C et al. Eur J Human Genetics April 29, 2015

Fine mapping in the MHC region accounts for 18% additional genetic risk for celiac disease
Gutierrez-Achury J et al. Nature Genetics, April 20, 2015

Coeliac disease - from genetic and immunological studies to clinical applications.
Lundin Knut EA et al. Scand. J. Gastroenterol. 2015 Apr 7. 1-10

Clinical features of celiac disease: a prospective birth cohort.
Agardh D et al. Pediatrics 2015 Apr (4) 627-34

Review and practice guidelines for celiac disease in 2014.
Nadhem ON et al. Postgrad Med 2015 Apr (3) 259-65

Autoimmune disease in first-degree relatives and spouses of individuals with celiac disease.
Emilsson L et al. Clin. Gastroenterol. Hepatol. 2015 Jan 31.

Lactase genetic polymorphisms and coeliac disease in children: a cohort study.
Kuchay RA et al. Ann. Hum. Biol. 2015 Jan (1) 101-4

Celiac disease as a model for the evolution of multifactorial disease in humans.
Sams A et al. Hum. Biol. 2014 (1) 19-36

Celiac Disease: Gluten, Genetics and Public Health - October 9, 2014

What is celiac disease? NIH Genetics Home Reference

Genetics of celiac disease, by Alessio Fasano, Medscape, August 2014

Introduction of gluten, HLA status, and the risk of celiac disease in children
Elena Lionetti et al. New England Journal of Medicine, October 1, 2014

The missing environmental factor in celiac disease.
Jonas F. Ludvigsson, et al. N Engl J Med 2014; 371:1341-1343

Risk of pediatric celiac disease according to HLA haplotype and country.
Edwin Liu et al. New England J Medicine, July 2014 

Gut reactions — from celiac affection to autoimmune model
Warwick H. Anderson, and Ian R. Mackay N Engl J Med 2014; 371:6-7 July 2014

The prevalence of celiac disease in the United States.
Rubio-Tapia A, et al. Am J Gastroenterol. 2012

Did you know? > 500 genes have been reported in relation to risk and outcomes of celiac disease, including 18 genomewide association studies? To find out more, visit the HuGE Navigator