domingo, 31 de mayo de 2015

Rotavirus. - PubMed - NCBI

Rotavirus. - PubMed - NCBI

 2015 Jun;35(2):363-391. doi: 10.1016/j.cll.2015.02.012.



Group A rotavirus (RVA) is the major cause of acute gastroenteritis (AGE) in young children worldwide. Introduction of two live, attenuated rotavirus vaccines, Rotarix® and RotaTeq®, has dramatically reduced RVA-associated AGE and mortality. High-throughput, sensitive and specific techniques are required to rapidly diagnose and characterize rotavirus strains in stool samples for proper patient treatment and to monitor circulating vaccine and wild-type rotavirus strains. New molecular assays are rapidly developed that are more sensitive and specific than the conventional assays for detection, genotyping and full genome characterization of circulating rotavirus wild-type and vaccine (Rotarix® and RotaTeq®) strains causing AGE.
Copyright © 2015 Elsevier Inc. All rights reserved.


Acute gastroenteritis; Multiplex assays; Next-generation sequencing; RotaTeq®; Rotarix®; Rotavirus; Rotavirus vaccines; qRT-PCR

[PubMed - as supplied by publisher]

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