Aging
Aging: Public Health & Genomic Insights - May 1, 2015
CDC information:Innovative strategies for healthy aging
Why is aging conserved and what can we do about It?![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Pitt JN et al. PLoS Biol. 2015 Apr (4) e1002131
Pitt JN et al. PLoS Biol. 2015 Apr (4) e1002131
DNA methylation and healthy human aging.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Jones MJ et al. Aging Cell 2015 Apr 25.
Jones MJ et al. Aging Cell 2015 Apr 25.
Genome-wide association studies of late-onset cardiovascular disease.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Smith JG et al. J. Mol. Cell. Cardiol. 2015 Apr 11.
Smith JG et al. J. Mol. Cell. Cardiol. 2015 Apr 11.
Developing vaccines for an aging population.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Black S et al. Sci Transl Med 2015 Apr 1. (281) 281ps8
Black S et al. Sci Transl Med 2015 Apr 1. (281) 281ps8
The role of telomeres and vitamin D in cellular aging and age-related diseases.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Pusceddu I et al. Clin. Chem. Lab. Med. 2015 Mar 21.
Pusceddu I et al. Clin. Chem. Lab. Med. 2015 Mar 21.
Extended fertility and longevity: the genetic and epigenetic link.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Wainer-Katsir K et al. Fertil. Steril. 2015 Mar 18.
Wainer-Katsir K et al. Fertil. Steril. 2015 Mar 18.
The aging clock and circadian control of metabolism and genome stability.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Belancio VP et al. Front Genet 2014 455
Belancio VP et al. Front Genet 2014 455
Subclinical carotid atherosclerosis and early vascular aging from long-term low-dose ionizing radiation exposure: a genetic, telomere, and vascular ultrasound study in cardiac catheterization laboratory staff.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Andreassi MG et al. JACC Cardiovasc Interv 2015 Apr 20. (4) 616-27
Andreassi MG et al. JACC Cardiovasc Interv 2015 Apr 20. (4) 616-27
Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Sharples AP et al. Aging Cell 2015 Apr 10.
Sharples AP et al. Aging Cell 2015 Apr 10.
From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Vel Szic KSc et al. Clin Epigenetics 2015 (1) 33
Vel Szic KSc et al. Clin Epigenetics 2015 (1) 33
Promoting health and longevity through diet: from model organisms to humans.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Fontana L et al. Cell 2015 Mar 26. (1) 106-118
Fontana L et al. Cell 2015 Mar 26. (1) 106-118
Genome-wide association study and linkage analysis of the healthy aging index.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Minster RL et al. J. Gerontol. A Biol. Sci. Med. Sci. 2015 Mar 10.
Minster RL et al. J. Gerontol. A Biol. Sci. Med. Sci. 2015 Mar 10.
Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Chauhan G et al. Neurobiol. Aging 2015 Apr (4) 1765.e7-1765.e16
Chauhan G et al. Neurobiol. Aging 2015 Apr (4) 1765.e7-1765.e16
Healthy Aging and Longevity: Role of Genomics - January 8, 2015
In a new approach to fighting disease, helpful genetic mutations are sought,
by Gina Kolata, New York Times, Dec 28, 2014
The Resilience Project: A search for unexpected heroes,
Icahn Mount Sinai, School of Medicine
The good mutations,
GenomeWeb, Dec 30, 2014 [by free subscription only]
Researchers examine supercentenarians' genomes for longevity key,
by Brooke Wolford, National Human Genome Research Institute, December 2014
Whole-genome sequencing of the world's oldest people.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Gierman HJ, et al. PLoS One. 2014 Nov 12;9(11):e112430
Gierman HJ, et al. PLoS One. 2014 Nov 12;9(11):e112430
Disease variants in genomes of 44 centenarians.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Freudenberg-Hua Y, et al. Mol Genet Genomic Med. 2014 Sep;2(5):438-50
Freudenberg-Hua Y, et al. Mol Genet Genomic Med. 2014 Sep;2(5):438-50
Why genes extending lifespan in model organisms have not been consistently associated with human longevity and what it means to translation research.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
de Magalhães JP. Cell Cycle. 2014 Sep 1;13(17):2671-3.
de Magalhães JP. Cell Cycle. 2014 Sep 1;13(17):2671-3.
GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Broer L, et al. J Gerontol A Biol Sci Med Sci. 2015 Jan;70(1):110-8.
Broer L, et al. J Gerontol A Biol Sci Med Sci. 2015 Jan;70(1):110-8.
Genetic analysis of long-lived families reveals novel variants influencing high density-lipoprotein cholesterol.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
Feitosa MF, et al. Front Genet. 2014 Jun 3;5:159
Feitosa MF, et al. Front Genet. 2014 Jun 3;5:159
Healthy Aging and Family History - October 31, 2013
CDC information: Healthy aging
NIH Senior Health: Why collect a family history?![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_tDi6j3k1p9CW3fwK58dJOPh4DhoUIQdEpD6QLKRpbGfeyOoCdYuNJ4Q3hIkmLykwG84cPR6CyxqinRxLL1zVRDPslVF8hxbk6iIx_2XaNoKxQ_Hl9wC8zI=s0-d)
You can use a family health history to see if you, your children, or your grandchildren might face an increased risk of developing serious health problems.
You can use a family health history to see if you, your children, or your grandchildren might face an increased risk of developing serious health problems.
CDC information: Family history and health
Most people have a family health history of some chronic diseases (e.g., cancer, coronary heart disease, and diabetes) and health conditions (e.g., high blood pressure and hypercholesterolemia).
Most people have a family health history of some chronic diseases (e.g., cancer, coronary heart disease, and diabetes) and health conditions (e.g., high blood pressure and hypercholesterolemia).
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