Aging
Aging: Public Health & Genomic Insights - May 1, 2015
CDC information:Innovative strategies for healthy aging
Why is aging conserved and what can we do about It?
Pitt JN et al. PLoS Biol. 2015 Apr (4) e1002131
Pitt JN et al. PLoS Biol. 2015 Apr (4) e1002131
DNA methylation and healthy human aging.
Jones MJ et al. Aging Cell 2015 Apr 25.
Jones MJ et al. Aging Cell 2015 Apr 25.
Genome-wide association studies of late-onset cardiovascular disease.
Smith JG et al. J. Mol. Cell. Cardiol. 2015 Apr 11.
Smith JG et al. J. Mol. Cell. Cardiol. 2015 Apr 11.
Developing vaccines for an aging population.
Black S et al. Sci Transl Med 2015 Apr 1. (281) 281ps8
Black S et al. Sci Transl Med 2015 Apr 1. (281) 281ps8
The role of telomeres and vitamin D in cellular aging and age-related diseases.
Pusceddu I et al. Clin. Chem. Lab. Med. 2015 Mar 21.
Pusceddu I et al. Clin. Chem. Lab. Med. 2015 Mar 21.
Extended fertility and longevity: the genetic and epigenetic link.
Wainer-Katsir K et al. Fertil. Steril. 2015 Mar 18.
Wainer-Katsir K et al. Fertil. Steril. 2015 Mar 18.
The aging clock and circadian control of metabolism and genome stability.
Belancio VP et al. Front Genet 2014 455
Belancio VP et al. Front Genet 2014 455
Subclinical carotid atherosclerosis and early vascular aging from long-term low-dose ionizing radiation exposure: a genetic, telomere, and vascular ultrasound study in cardiac catheterization laboratory staff.
Andreassi MG et al. JACC Cardiovasc Interv 2015 Apr 20. (4) 616-27
Andreassi MG et al. JACC Cardiovasc Interv 2015 Apr 20. (4) 616-27
Longevity and skeletal muscle mass: the role of IGF signalling, the sirtuins, dietary restriction and protein intake.
Sharples AP et al. Aging Cell 2015 Apr 10.
Sharples AP et al. Aging Cell 2015 Apr 10.
From inflammaging to healthy aging by dietary lifestyle choices: is epigenetics the key to personalized nutrition?
Vel Szic KSc et al. Clin Epigenetics 2015 (1) 33
Vel Szic KSc et al. Clin Epigenetics 2015 (1) 33
Promoting health and longevity through diet: from model organisms to humans.
Fontana L et al. Cell 2015 Mar 26. (1) 106-118
Fontana L et al. Cell 2015 Mar 26. (1) 106-118
Genome-wide association study and linkage analysis of the healthy aging index.
Minster RL et al. J. Gerontol. A Biol. Sci. Med. Sci. 2015 Mar 10.
Minster RL et al. J. Gerontol. A Biol. Sci. Med. Sci. 2015 Mar 10.
Association of Alzheimer's disease GWAS loci with MRI markers of brain aging.
Chauhan G et al. Neurobiol. Aging 2015 Apr (4) 1765.e7-1765.e16
Chauhan G et al. Neurobiol. Aging 2015 Apr (4) 1765.e7-1765.e16
Healthy Aging and Longevity: Role of Genomics - January 8, 2015
In a new approach to fighting disease, helpful genetic mutations are sought, by Gina Kolata, New York Times, Dec 28, 2014
The Resilience Project: A search for unexpected heroes, Icahn Mount Sinai, School of Medicine
The good mutations, GenomeWeb, Dec 30, 2014 [by free subscription only]
Researchers examine supercentenarians' genomes for longevity key, by Brooke Wolford, National Human Genome Research Institute, December 2014
Whole-genome sequencing of the world's oldest people.
Gierman HJ, et al. PLoS One. 2014 Nov 12;9(11):e112430
Gierman HJ, et al. PLoS One. 2014 Nov 12;9(11):e112430
Disease variants in genomes of 44 centenarians.
Freudenberg-Hua Y, et al. Mol Genet Genomic Med. 2014 Sep;2(5):438-50
Freudenberg-Hua Y, et al. Mol Genet Genomic Med. 2014 Sep;2(5):438-50
Why genes extending lifespan in model organisms have not been consistently associated with human longevity and what it means to translation research.
de Magalhães JP. Cell Cycle. 2014 Sep 1;13(17):2671-3.
de Magalhães JP. Cell Cycle. 2014 Sep 1;13(17):2671-3.
GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.
Broer L, et al. J Gerontol A Biol Sci Med Sci. 2015 Jan;70(1):110-8.
Broer L, et al. J Gerontol A Biol Sci Med Sci. 2015 Jan;70(1):110-8.
Genetic analysis of long-lived families reveals novel variants influencing high density-lipoprotein cholesterol.
Feitosa MF, et al. Front Genet. 2014 Jun 3;5:159
Feitosa MF, et al. Front Genet. 2014 Jun 3;5:159
Healthy Aging and Family History - October 31, 2013
CDC information: Healthy aging
NIH Senior Health: Why collect a family history?
You can use a family health history to see if you, your children, or your grandchildren might face an increased risk of developing serious health problems.
You can use a family health history to see if you, your children, or your grandchildren might face an increased risk of developing serious health problems.
CDC information: Family history and health
Most people have a family health history of some chronic diseases (e.g., cancer, coronary heart disease, and diabetes) and health conditions (e.g., high blood pressure and hypercholesterolemia).
Most people have a family health history of some chronic diseases (e.g., cancer, coronary heart disease, and diabetes) and health conditions (e.g., high blood pressure and hypercholesterolemia).
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