Toxicological Profiles
Information About Contaminants Found at Hazardous Waste Sites
Substance Index for ToxProfiles
Finalized toxicological profiles by chemical with NTIS order number. Updates are in bold.
* denotes tox profiles funded by the Department of Defense.
* denotes tox profiles funded by the Department of Defense.
Background
By Congressional mandate, the Agency for Toxic Substances and Disease Registry (ATSDR) produces "toxicological profiles" for hazardous substances found at National Priorities List (NPL) sites. These hazardous substances are ranked based on frequency of occurrence at NPL sites, toxicity, and potential for human exposure. Toxicological profiles are developed from a priority list of 275 substances. ATSDR also prepares toxicological profiles for the Department of Defense (DOD) and the Department of Energy (DOE) on substances related to federal sites.
Toxicological profiles are developed in two stages:
(1) DRAFTS: The toxicological profiles are first produced as drafts. ATSDR announces in the Federal Register the release of these draft profiles for a 90 day public comment period. Request draft toxicological profiles from ATSDR's Division of Toxicology and Human Health Sciences.
(2) FINALS: After the 90 day comment period, ATSDR considers incorporating all comments into the documents. ATSDR finalizes the profiles.
NTIS address
NTIS distributes finalized toxicological profiles for a fee. For more information, contact
National Technical Information Service
5285 Port Royal Road
Springfield, Virginia 22161
1-800-553 6847 or 703-605-6000
Web site: http://www.ntis.gov
- Trichlorobenzenes
- Toxaphene (Update)
- Perfluoroalkyls
The public comment period has ended and the profiles will be revised based on relevant public comments.
The public comment period has ended and the profiles will be revised based on relevant public comments.
- Glutaraldehyde*
- Hydrogen Sulfide/Carbonyl Sulfide (Update)
- Parathion
- Tetrachloroethylene (Update)
- Trichloroethylene (Update)
The public comment period ends on March 15, 2015.
*Glutaraldehyde is on a modified schedule and still under development.
- DEET
- Toluene Diisocyanate
- Nitrates/Nitrites
- Toluene (Update)
- Polybrominated Diphenyl Ethers (Update)
- Molybdenum
- Antimony (Update)
- 2,4-D
- Glyphosate
- Silica
- 1-Bromopropane
List updated on December 12, 2014
Federal Register Notices:
- FRN RDX [PDF, 51 KB]
- FRN Uranium [PDF, 52 KB]
- FRN Set 24 Drafts for Public Comment [PDF, 46 KB]
- FRN Set 21 Final Profiles [PDF, 42 KB]
Profile Development:
- Profile Development Guidance [PDF, 2 MB]
- Profile Development Guidance Exhibits [PDF, 1 MB]
- Profile Selection Criteria
- Federal Register Notice [PDF, 964 KB]
- Support Document [PDF, 2.6 MB]
Additional Resources:
- Public Health Statements (PHS) - The PHS are a series of summaries about hazardous substances taken from Chapter One of their respective ATSDR Toxicological Profiles.
- ATSDR ToxFAQsTM - The ToxFAQsTM are a series of 2-page fact sheets about hazardous substances
- ATSDR ToxGuidesTM - The ATSDR ToxGuidesTM are quick reference guides providing information such as chemical and physical properties, sources of exposure, routes of exposure, minimal risk levels, children's health, and health effects.
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