jueves, 8 de enero de 2015

ATSDR - Minimal Risk Levels for Hazardous Substances (MRLs)

ATSDR - Minimal Risk Levels for Hazardous Substances (MRLs)



Minimal Risk Levels (MRLs) List




Resources for Toxic Substances


  • Addendum to the Profile 
    • The purpose of Toxicological Profiles Addenda is to provide, to the public and other federal, state, and local agencies a non-peer reviewed supplement of the scientific data that were published in the open peer-reviewed literature since the release of the profile.

  • Case Study in Environmental Medicine (CSEM) 
    • Self-instructional publication designed to increase primary care provider's knowledge of a hazardous substance in the environment and to aid in the evaluation of potentially exposed patients.

  • Community Environmental Health Presentations 
    • CEHPs include information about specific types of exposures to hazardous substances, exposure routes and pathways, health effects, and how to prevent and minimize exposures.

  • Grand Rounds in Environmental Medicine 
    • Grand Rounds in Environmental Medicine (GREM) are 1-hour continuing-education seminars designed to increase the primary care provider's knowledge of hazardous substances in the environment and to aid in the evaluation of potentially exposed patients. The GREM seminars are available and downloadable online in two versions. The first version is scripted PowerPoint presentations ready for medical educators to use in face-to-face sessions with primary health-care providers, medical students, and others. The second version is a video recorded presentation that can be viewed online by individuals or groups. Both versions offer approved continuing education credits.

  • Interaction Profiles 
    • Succinctly characterizes the toxicologic and adverse health effects information for mixtures of hazardous substances.

  • Managing Hazardous Materials Incidents (MHMIs) 
    • What is the managing hazardous material incidents (MHMI) series?
      The MHMI series is a three volume set (with a video) comprised of recommendations for on-scene (pre-hospital), and hospital medical management of patients exposed during a hazardous materials incident.

  • Medical Management Guidelines (MMG) for Acute Chemical Exposure 
    • Medical Management Guideline (MMG) for Acute Chemical Exposure Publication intended to aid emergency department physicians and other emergency healthcare professionals who manage acute exposures.

  • Minimal Risk Levels (MRL) 
    • The MRL is an estimate of the daily human exposure to a hazardous substance that is likely to be without appreciable risk of adverse, non-cancer health effects over a specified duration of exposure. The information in this MRL serves as a screening tool to help public health professionals decide where to look more closely to evaluate possible risk of adverse health effects from human exposure.

  • Mixtures Guidance Manual 
    • Provides guidance for assessment of joint toxicity of environmental chemicals to determine whether exposure to chemical mixtures may impact public health.

  • Patient Education and Care Instruction Sheet 
    • Patient Education and Care Instruction Sheets complement the newly developed or revised CSEM and GREM topics. These job aids provide general information on various environmental medicine topics and give health-care providers quick, ready-to-use materials to aid in patient care and instruction. Patient Education and Care Instruction Sheets are available and downloadable online. These education sheet are made available for use with patients and do not offer continuing education credit for their use.

  • Pediatric Environmental Health Training 
    • Pediatric Environmental Health Training provides in-depth information The Pediatric Environmental Health Toolkit (PEHT) offers health-care providers detailed examples about how to best deliver anticipatory guidance on a range of environmental health issues, especially during well-child visits.

  • Priority Data Needs 
    • The priority data needs represent essential information to improve the database for conducting public health assessments.

  • Priority List of Hazardous Substances 
    • Prioritization of substances based on a combination of their frequency, toxicity, and potential for human exposure at National Priorities List (NPL) sites.

  • Public Health Statement 
    • Summary about a hazardous substance taken from Chapter One of its respective ATSDR Toxicological Profile.

  • Scientific Assessments and Consultations 
    • This section provides technical information to scientists and public health and medical professionals on the effects of DEET.

  • ToxFAQs 
    • The ATSDR ToxFAQs™ are summaries about hazardous substances developed by the ATSDR Division of Toxicology and Human Health Sciences. Information for this series is excerpted from the ATSDR Toxicological Profiles (read more about ToxProfiles) and Public Health Statements. Each fact sheet serves as a quick and easy to understand guide. Answers are provided to the most frequently asked questions (FAQs) about exposure to hazardous substances found around hazardous waste sites and the effects of exposure on human health.

  • ToxGuide 
    • Quick reference guide providing information such as chemical and physical properties, sources of exposure, routes of exposure, minimal risk levels, children's health, and health effects for a substance.

  • Toxicological Profile 
    • Succinctly characterizes the toxicologic and adverse health effects information for a hazardous substance.

  • Toxicology Curriculum for Communities Trainer's Manual 
    • The Toxicology Curriculum for Communities Trainer's Manual is a result of the collaborative efforts that would lead to greater community commitment, and would provide greater insight into gaps in toxicology knowledge. The manual provides four training modules for lectures or seminars for communities, on the topic of toxicology and issues surrounding environmental exposures.

  • ToxZine 


  • How do I contact ATSDR?

    Agency for Toxic Substances and Disease Registry 
    Division of Toxicology and Human Health Sciences
    1600 Clifton Road NE, Mailstop F-57
    Atlanta, GA 30333 
    Phone: 1- 800-CDC-INFO 888-232-6348 (TTY)
    Email: cdcinfo@cdc.gov 

    Health Effects of Exposure to Substances and Carcinogens


    Health Effects: Cancer, and Organ Systems and their developmentAn organ system is a structure that is found inside a human or animal. It is made of cells or tissues that perform a specific function. When exposed to a hazardous substance, the organ that the substance affects at the lowest dose is called the target organ. Development is the process in which an individual or animal matures until puberty. Click on a target organ system below to see an overview of the system and a list of substances that can harm it.

    Cancer Classification


    Effects of Toxic Substances on Organ Systems and their Development

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