Gene Therapy & Gene Editing: Recent Insights

Genomics|Update|Current

Gene Therapy & Gene Editing: Recent Insights

In hopes of fixing faulty genes, one scientist starts with the basics, by Joe Palca, National Public Radio, Oct 13

Advances in CRISPR genome-editing, PHG Foundation, Oct 7

CRISPR-Cas9 knockin mice for genome editing and cancer modeling.
Platt RJ, et al. Cell. 2014 Oct 9;159(2):440-55.

Sequence-specific antimicrobials using efficiently delivered RNA-guided nucleases
Citorik RJ, et al. Nat Biotechnol. 2014 Sep 21.

Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials.
Bikard D, et al. Nat Biotechnol. 2014 Oct 5.

RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection
Hu W, et al.  PNAS, Jul 21, 2014.

Genome editing cuts out HIV
Grens K. The Scientist, Jul 21, 2014.

Gene researchers work to engineer HIV-resistant cells 
Hampton T. JAMA, Jul 9, 2014.

Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV
Tebas P, et al. N Engl J Med. 2014 Mar 6;370(10):901-10.

Promising results from HIV gene editing therapy, PHG Foundation, Mar 10