Infectious Diseases

Genomics|Update|Current

Infectious Diseases

Superbugs meet their match in rapid genome sequencing. Close to real-time tracking of deadly superbugs such as MRSA promises to close down outbreaks faster and save lives. Ian Sample, the Guardian, Sep 12

Vaginal microbe yields novel antibiotic. Drug is one of thousands that may be produced by the human microbiome, by Erika Check Hayden, Nature News, Sep 11 

Emerging viral diseases: confronting threats with new technologies
Marston HD, et al. Sci Transl Med 2014; 6(253): 253ps10. 

Ancient-pathogen genomics: coming of age?
Whatmore AM. mBio 2014;5(5):01676-14.

Serotyping of pneumococci: evaluation of the genetic approach and performance with clinical samples
Burckhardt I, et al. Diag Microbiol Infect Dis, Sep 2, 2014.

Point-of-care testing for Clostridium difficile infection: a real-world feasibility study of a rapid molecular test in two hospital settings
Goldenberg SD, et al. Infect Dis Ther, Sep 10, 2014.

Evaluation of the illumigene C. difficile assay for toxigenic Clostridium difficile detection: a prospective study of 302 consecutive clinical fecal samples
Hong G, et al. Diag Microbiol Infect Dis, Sep 5, 2014.

Cost and impact on patient length of stay of rapid molecular testing for Clostridium difficile
Sewell B, et al. Infect Dis Ther, Sep 3, 2014.

Rapid point of care diagnostic tests for viral and bacterial respiratory tract infections—needs, advances, and future prospects
Zumla A, et al. Lancet Infect Dis, Sep 1, 2014.

Infectious diseases and tropical disease pathology: SC16-1 Needle in a haystack: the new world of diagnostics for micro-organisms
Milner DA Jr. Pathology. 2014 Oct;46 Suppl 2:S26.

Transcriptional correlates of disease outcome in anticoagulant-treated non-human primates infected with Ebolavirus
Garamszegi S, et al. PLoS Negl Trop Dis 8(7): e3061.

HLA Class I and KIR genes do not protect against HIV type 1 infection in highly exposed uninfected individuals with hemophilia A
Vince N, et al. Infect Dis. 2014; 210(7): 1047-1051.

Genomic surveillance elucidates Ebola virus origin and transmission during the 2014 outbreak 
Stephen K. Gire, et al. Science, September 12, 2014

Accuracy of urinary human papillomavirus testing for presence of cervical HPV: systematic review and meta-analysis. 
BMJ 2014; 349

Urine testing for HPV. 
Henry C Kitchener. BMJ 2014; 349