Multistate Meningitis Outbreak Investigation
October 11, 2012 4:30 AM EDT
Current Situation
- As of October 10, 2012, CDC’s fungal disease laboratory has confirmed the presence of the fungus Exserohilum in 10 people with meningitis and the fungus Aspergillus in one person with meningitis.
- Clinicians should continue to contact patients who have received medicines associated with three lots of preservative-free methylprednisolone acetate (80mg/ml) from the New England Compounding Center (NECC) that were recalled on September 26, 2012. The potentially contaminated injections were given starting May 21, 2012. See updated Clinician Guidance webpage for more information.
- CDC's guidance to patients has not changed as a result of the expanded voluntary recall of all NECC products
, announced October 6. Patients who feel ill and are concerned about whether they received a medication from one of the NECC products recalled on September 26 should contact their physician.
- Onset of symptoms is typically 1 to 4 weeks following injection, but there are also reports of shorter and longer periods of time between injection and onset of symptoms. See updated Patient Guidance.
CDC Responds to Multistate Meningitis Outbreak:
The Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) are currently coordinating a multistate investigation of fungal meningitis among patients who received an epidural steroid injection with a potentially contaminated product. This form of meningitis is not contagious. Several of these patients also suffered strokes that are believed to have resulted from their infection.
The Centers for Disease Control and Prevention (CDC) and the Food and Drug Administration (FDA) are currently coordinating a multistate investigation of fungal meningitis among patients who received an epidural steroid injection with a potentially contaminated product. This form of meningitis is not contagious. Several of these patients also suffered strokes that are believed to have resulted from their infection.
Clinician & Patient Guidance
Additional Federal Agencies Involved:
(FDA)
At-A-Glance
- Status: Ongoing Investigation
- Infection: Fungal Meningitis
- Facility Type: Outpatient Setting
- Case Count: 137
- States: 10
- Deaths: 12
Current Case Count Map:
Click to view case count map.
Click to view case count map. Current State Facilities Map:
Click to view facilities map.
Click to view facilities map. Related Links
For Clinicians
- Frequently Asked Questions For Clinicians: Multistate Meningitis Outbreak Investigation Updated: Oct 10, 2012
Health Alert Network
- CDC Health Alert Network (HAN): Multistate Outbreak of Meningitis and Stroke Associated with Potentially Contaminated Steroid Medication NEW: OCT 8, 2012
- CDC Health Alert Network (HAN): Meningitis and Stroke Associated with Potentially Contaminated Product New: Oct 4, 2012
Guidance
- Interim Treatment Guidance for Central Nervous System and/or Parameningeal Infections Associated with Injection of Potentially Contaminated Steroid Products UPDATED: Oct 10, 2012
Case Definitions
- Case Definitions for Meningitis and Septic Arthritis New: Oct 10, 2012
Testing
- Instructions for Clinical Teams Regarding Diagnostic Testing and Specimen Submission to CDC – Outbreak Associated With Injection of Potentially Contaminated Steroid Products Updated: Oct 8, 2012
- Lumbar puncture in asymptomatic patients New: Oct 6, 2012
Prophylaxis
- Role of antifungal prophylaxis in asymptomatic patients UPDATED: OCt 10, 2012
For Patients and the Public
- Frequently Asked Questions for Patients UPDATED: OCt 10, 2012
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