domingo, 31 de julio de 2011

WNV in Killer Whale | CDC EID :: Volume 17, Number 8–August 2011

full-text ►WNV in Killer Whale | CDC EID: "EID Journal Home > Volume 17, Number 8–August 2011
Volume 17, Number 8–August 2011
West Nile Virus Infection in Killer Whale, Texas, USA, 2007

Judy St. Leger, Comments to Author Guang Wu, Mark Anderson, Les Dalton, Erika Nilson, and David Wang

Author affiliations: SeaWorld, San Diego, California, USA (J. St. Leger, E. Nilson); Washington University School of Medicine, St. Louis, Missouri, USA (G. Wu, D. Wang); University of California at Davis, Davis, California, USA (M. Anderson); and SeaWorld, San Antonio, Texas, USA (L. Dalton)

Suggested citation for this article

In 2007, nonsuppurative encephalitis was identified in a killer whale at a Texas, USA, marine park. Panviral DNA microarray of brain tissue suggested West Nile virus (WNV); WNV was confirmed by reverse transcription PCR and sequencing. Immunohistochemistry demonstrated WNV antigen within neurons. WNV should be considered in cases of encephalitis in cetaceans.

West Nile virus (WNV) is a single-stranded RNA virus of the genus Flavivirus that is transmitted by mosquitoes. In humans and animals, WNV has been associated with a spectrum of clinical conditions from asymptomatic infections to sudden death. These have been identified in a variety of animal species. Among marine mammals, WNV infection has been reported in a harbor seal (Phoca vitulina) (1). We describe WNV infection in a killer whale (Orcinus orca) and seroprevalence in conspecific cohort and noncohort groups.

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Suggested Citation for this Article

St. Leger J, Wu G, Anderson M, Dalton L, Nilson E, Wang D. West Nile virus infection in killer whale, Texas, USA, 2007. Infect Dis [serial on the Internet]. 2011 Aug [date cited].

DOI: 10.3201/eid1708.101979

Comments to the Authors

Please use the form below to submit correspondence to the authors or contact them at the following address:

Judy St. Leger, 500 SeaWorld Dr., San Diego, CA 92109, USA, email:

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