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Volume 17, Number 8–August 2011
Novel GII.12 Norovirus Strain, United States, 2009–2010
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Author affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Suggested citation for this article
In October 2009, a novel GII.12 norovirus strain emerged in the United States and caused 16% of all reported norovirus outbreaks during the winter season. Sequence analysis demonstrated a recombinant virus with a P2 region that was largely conserved compared with previously sequenced GII.12 strains.
Noroviruses are the leading cause of viral gastroenteritis outbreaks in the United States (1). Over the past decade most norovirus outbreaks have been caused by genogroup (G) II.4 noroviruses, while each of the other genotypes did not cause >7% of the outbreaks (2,3). However, previous studies have suggested that non-GII.4 noroviruses have been predominant in the past (3,4). For example, analysis of archived samples from 1974 through 1991 has shown that the frequency of GII.3 was 48% compared with 16% for GII.4 and 14% for GII.7 strains (3). Therefore, it is essential to study sudden increases of non-GII.4 strains to determine possible signatures that could be associated with increased transmissibility or population susceptibility. In this article, we describe the emergence of a novel GII.12 strain in the United States in the winter of 2009–10 that was associated with a large number of the norovirus outbreaks.
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Suggested Citation for this Article
Vega E, Vinjé J. Novel GII.12 norovirus strain, United States, 2009–2010. Emerg Infect Dis [serial on the Internet]. 2011 Aug [date cited]. http://www.cdc.gov/EID/content/17/8/110025.htm
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Everardo Vega, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, Mailstop G04, Atlanta, GA 30333, USA; email: email@example.com
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