Study aims to understand molecular origins of CTNNB1 neurodevelopmental syndrome

https://www.news-medical.net/news/20260227/Study-aims-to-understand-molecular-origins-of-CTNNB1-neurodevelopmental-syndrome.aspx On the occasion of Rare Disease Day, the Biofisika Institute (CSIC, EHU) presents the progress of a project aimed at understanding the molecular origin of CTNNB1 neurodevelopmental syndrome, a rare disease caused by mutations in the beta-catenin protein. Although fewer than 50 cases of this pathology have been diagnosed in Spain, rare diseases affect a total of nearly three million people.

What is Mycelium? Health Benefits, Nutrition Facts, and Sustainability Explained

https://www.news-medical.net/health/What-is-Mycelium-Health-Benefits-Nutrition-Facts-and-Sustainability-Explained.aspx Whole-food mycelium, which originates from filamentous fungi such as Fusarium venenatum and Pleurotus species, is currently being evaluated for its potential as an alternative protein source to conventional meat- or plant-based foods. Unlike soy or pea protein, which undergo extensive fractionation and isolation of specific bioactive components, mycelium maintains a complex whole-food matrix that mimics the fibrous structure of animal tissue while delivering a bioavailable amino acid profile.1,4

Why Mankai (Wolffia globosa) Is Emerging as a Functional Food for Metabolic Health

https://www.news-medical.net/health/Why-Mankai-(Wolffia-globosa)-Is-Emerging-as-a-Functional-Food-for-Metabolic-Health.aspx Mankai (Wolffia globosa) is a fast-growing aquatic plant of the duckweed family that contains high-quality plant protein, including all the essential amino acids, as well as dietary fiber and a broad spectrum of micronutrients like iron, folate, and authentic (bioactive) vitamin B12 forms identified by LC-MS/MS (including OH-B12, Ado-B12, Me-B12, and CN-B12). In analyses comparing Mankai extracts with spirulina, no pseudo-vitamin B12 (pseudo-CN-B12) was detected in Mankai. In controlled dietary interventions, Mankai has commonly been provided as ~100 g frozen biomass/day blended into a “green shake”. Due to its mild flavor and smooth texture, Mankai is an emerging ingredient in dried powders, frozen shakes and smoothies, and other functional food items.1

Are Precision-Fermented Fats Healthier Than Traditional Dairy Fat?

https://www.news-medical.net/health/Are-Precision-Fermented-Fats-Healthier-Than-Traditional-Dairy-Fat.aspx Precision-fermented, dairy-identical fats are lipids produced using advanced microbial fermentation processes, rather than traditional animal agriculture. During precision fermentation, selected microorganisms, such as yeasts or fungi, are engineered and cultivated to synthesize fats that structurally and functionally resemble those in conventional dairy products.

Can peanut butter improve mobility after 65?

https://www.news-medical.net/news/20260227/Can-peanut-butter-improve-mobility-after-65.aspx A simple spoonful of peanut butter each day improved lower-body muscle power in older adults, but the study’s primary walking test did not budge, highlighting both the promise and the limits of diet-only strategies for healthy aging.

Gut microbiome may shape response to GLP-1 drugs, new review suggests +++++

Gut microbiome may shape response to GLP-1 drugs, new review suggests https://www.news-medical.net/news/20260219/Gut-microbiome-may-shape-response-to-GLP-1-drugs-new-review-suggests.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=bowel_cancer_newsletter_24_february_2026 Gut microbiome may shape response to GLP-1 drugs, new review suggestsThis review examines how GLP-1 receptor agonists and the gut microbiome influence one another through bile acid signaling, short-chain fatty acids, and inflammatory pathways. It explores how microbial composition may shape treatment response and highlights the need for controlled human studies to enable microbiome-informed precision therapy. AI tool can accurately predict colorectal cancer risk in UC-LGD patients https://www.news-medical.net/news/20260217/AI-tool-can-accurately-predict-colorectal-cancer-risk-in-UC-LGD-patients.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=bowel_cancer_newsletter_24_february_2026 AI tool can accurately predict colorectal cancer risk in UC-LGD patientsPeople with ulcerative colitis (UC), a chronic inflammatory bowel disease, are up to four times more likely to develop colorectal cancer than the general population. Developmental ANGPTL4 deficiency protects mice from colitis and tumors https://www.news-medical.net/news/20260218/Developmental-ANGPTL4-deficiency-protects-mice-from-colitis-and-tumors.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=bowel_cancer_newsletter_24_february_2026 Developmental ANGPTL4 deficiency protects mice from colitis and tumorsA novel study using a mouse model has found that the absence of the angiopoietin-like 4 (ANGPTL4) protein during development triggers a long-lasting reprogramming of the immune system that protects against intestinal inflammation. Distinct gut toxicity patterns emerge with targeted cancer treatments https://www.news-medical.net/news/20260220/Distinct-gut-toxicity-patterns-emerge-with-targeted-cancer-treatments.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=bowel_cancer_newsletter_24_february_2026 A new paper was published in Volume 13 of Oncoscience on February 6, 2026, titled "Gastrointestinal toxicity of targeted cancer therapies in the United States: Clinicopathologic patterns, FDA safety frameworks, and implications for national patient protection." Study reveals bacterial duo driving chronic constipation https://www.news-medical.net/news/20260219/Study-reveals-bacterial-duo-driving-chronic-constipation.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=bowel_cancer_newsletter_24_february_2026 Scientists at Nagoya University in Japan have found two gut bacteria working together that contribute to chronic constipation.

Screening helps detect colorectal cancer at an early stageScreening helps detect colorectal cancer at an early stage +++

Screening helps detect colorectal cancer at an early stageScreening helps detect colorectal cancer at an early stage https://www.news-medical.net/news/20260220/Screening-helps-detect-colorectal-cancer-at-an-early-stage.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=bowel_cancer_newsletter_24_february_2026 More cases of colorectal cancer are detected at an early stage with screening. This is according to new research based on data from over 278,000 60-year-olds, who were randomly selected to undergo one of two interventions or no screening at all (usual care). Gut bacteria patterns help predict insulin resistance in type 2 diabetes, study findsGut bacteria patterns help predict insulin resistance in type 2 diabetes, study finds https://www.news-medical.net/news/20260219/Gut-bacteria-patterns-help-predict-insulin-resistance-in-type-2-diabetes-study-finds.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=bowel_cancer_newsletter_24_february_2026 Researchers used 16S rRNA sequencing and machine learning to identify gut microbiome patterns associated with insulin resistance severity in people with type 2 diabetes. XGBoost models showed that specific bacterial genera, including Bacteroides and Faecalibacterium, help distinguish individuals with higher insulin resistance from healthy controls. Study identifies distinctive feature of tissues from young patients with colorectal cancerStudy identifies distinctive feature of tissues from young patients with colorectal cancer https://www.news-medical.net/news/20260217/Study-identifies-distinctive-feature-of-tissues-from-young-patients-with-colorectal-cancer.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=bowel_cancer_newsletter_24_february_2026 A study co-led by University of Texas at Dallas bioengineers identified a distinctive feature of tissues from young patients diagnosed with colorectal cancer, a disease that typically affects older patients.