A Man on Ibrutinib Develops Cerebral Aspergillosis Wolfgang Paik

https://www.medscape.com/viewarticle/man-ibrutinib-develops-cerebral-aspergillosis-2026a100173i?src= Cerebral aspergillosis can present without fever or systemic inflammation in patients receiving targeted hematologic therapies, with subtle cognitive, language, and gait deficits that may mimic those of stroke or encephalopathy. Although neuroimaging can identify multifocal enhancing lesions with extensive edema, it may not distinguish fungal, bacterial, or neoplastic diseases. Therefore, histopathologic examination of resected tissue may be necessary to establish a diagnosis.