When Can Skin Biopsies Miss the Correct Diagnosis? Elisa Riera, MD

https://www.medscape.com/viewarticle/when-can-skin-biopsies-miss-correct-diagnosis-2026a10015jz?src= When clinicians suspect an inflammatory skin disease, the standard approach is usually to perform a skin biopsy and prescribe a corticosteroid while awaiting the results. However, the diagnostic accuracy depends on the lesion selected, the sampling technique, and the clinical information accompanying the specimen. Information can be lost at multiple stages between tissue sampling and the final pathology report.