Researchers mine cobra toxins to uncover a membrane-disrupting antimicrobial peptide

https://www.news-medical.net/news/20260917/Researchers-mine-cobra-toxins-to-uncover-a-membrane-disrupting-antimicrobial-peptide.aspx A computational search of cobra cardiotoxins put 14 venom-inspired peptides through structural, antibacterial, and toxicity testing, providing a rigorous test of how far AI-guided peptide discovery can go. A recent study in the journal NPJ Drug Discovery identified and evaluated antimicrobial peptide candidates derived from cobra cardiotoxins using computational mining, machine learning prioritization, and experimental screening to test a toxin-inspired route to antimicrobial drug discovery.