Ending HIV: a reality check The Lancet +... ++

https://www.thelancet.com/journals/lancet/issue/vol408no10550/PIIS0140-6736(26)X2025-6 The fifth UN High-Level Meeting on HIV/AIDS (June 22–23) saw the agreement of a new Political Declaration on HIV/AIDS. In it, countries expressed commitments to end AIDS as a public health threat by 2030, mobilise adequate resources, achieve the 95–95–95 targets, and accelerate equitable access to comprehensive HIV prevention, among other provisions. Speaking to the press ahead of the meeting, Winnie Byanyima, Executive Director of UNAIDS, identified the four foundations of global HIV control that she hoped countries would support: multilateralism, sustained financing, protection of rights, and access to innovations. The difficulty for the Declaration is that each of these four dimensions is facing stark opposition, if not outright reversal A case of acute necrotising encephalitis secondary to human herpesvirus 6 infection Gregory Shinaman, MDa Send email to gregory_shinaman@urmc.rochester.edu ∙ Emily Lewandowski, BSc ∙ Gabriella Wozniak, DOa ∙ Jeffrey Guo, MDa ∙ Robert Thompson-Stone, MDb ∙ Laura Owlett, MDb ∙ et al. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00252-7/abstract?dgcid=raven_jbs_etoc_feature_lancet Orforglipron compared with dapagliflozin in adults with type 2 diabetes and inadequate glycaemic control with metformin (ACHIEVE-2): a multicentre, randomised, non-inferiority, open-label, phase 3 trial Michelle Welch, MDa ∙ Thomas Forst, MDb,c ∙ Prof Weiping Jia, MDd ∙ Pedro Orozco del Pino, PhDe ∙ Max Denning, MDe ∙ Wen-Shuo Wu, MDe ∙ et al. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00800-7/abstract?dgcid=raven_jbs_etoc_feature_lancet