Cannabis use in adolescence associated with higher rates of psychiatric disorders

https://www.news-medical.net/news/20260220/Cannabis-use-in-adolescence-associated-with-higher-rates-of-psychiatric-disorders.aspx Adolescents who use cannabis could face a significantly higher risk of developing serious psychiatric disorders by young adulthood, according to a large new study published today in JAMA Health Forum. The longitudinal study followed 463,396 adolescents ages 13 to 17 through age 26 and found that past-year cannabis use during adolescence was associated with a significantly higher risk of incident psychotic (doubled), bipolar (doubled), depressive and anxiety disorders. The study was conducted by researchers from Kaiser Permanente, the Public Health Institute's Getting it Right from the Start, the University of California, San Francisco and the University of Southern California, and was funded by a grant from NIH's National Institute on Drug Abuse (R01DA0531920).

Discovery offers hope for reducing immune-related heart risks in cancer patients

https://www.news-medical.net/news/20260220/Discovery-offers-hope-for-reducing-immune-related-heart-risks-in-cancer-patients.aspx For many people diagnosed with cancer, treatment with immune checkpoint inhibitors (ICIs) has dramatically extended lives. Some of these treatments, such as Keytruda and Opdivo, have become familiar brand names.

Social media exposure associated with steroid use intentions among boys and men

https://www.news-medical.net/news/20260220/Social-media-exposure-associated-with-steroid-use-intentions-among-boys-and-men.aspx A new study of more than 1,500 boys and men in Canada and the United States suggests that social media may play a meaningful role in shaping intentions to use anabolic-androgenic steroids (AAS), particularly when users are exposed to muscularity-focused content and engage in body comparisons online.

Single prenatal exposure to fungicide linked to disease across 20 generations

https://www.news-medical.net/news/20260220/Single-prenatal-exposure-to-fungicide-linked-to-disease-across-20-generations.aspx A single exposure to a toxic fungicide during pregnancy can increase the risk of disease for 20 subsequent generations - with inherited health problems worsening many generations after exposure.

Indoor air quality plays major role in adult asthma symptoms

https://www.news-medical.net/news/20260220/Indoor-air-quality-plays-major-role-in-adult-asthma-symptoms.aspx For adults with asthma, having fans, air purifiers or other ventilation and exhaust systems - especially in kitchens and bathrooms - is one of the best ways to reduce the risk of flare-ups at home.

Plasma brain-derived tau (BD-Tau) as a biomarker in Alzheimer’s disease and acute neurological disorders

https://www.news-medical.net/whitepaper/20260220/Plasma-brain-derived-tau-(BD-Tau)-as-a-biomarker-in-Alzheimere28099s-disease-and-acute-neurological-disorders.aspx The identification and validation of biomarkers for neurodegenerative diseases - particularly Alzheimer’s disease (AD) - is advancing rapidly. These biomarkers play a critical role in enabling early diagnosis, tracking disease progression, and assessing how patients respond to treatment.

Endocrine Therapies in ER-Positive/HER2-Negative MBC: Understanding Their Benefits and Limitations to Optimize Treatment Selection Authors: Joyce A. O’Shaughnessy, MD; Aditya Bardia, MD, MPH, FASCO

https://www.medscape.org/viewarticle/1003008?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260220-OUS-HONC-1003008-cta

Advancing Personalized Care for Prostate Cancer: Patient-Centered Solutions for mHSPC and nmCRPC Authors: Alicia K. Morgans, MD, MPH, FASCO; Christian Gratzke, MD; Fred Saad, MD, FRCS, FCAHS; Tony Collier, BEM

https://www.medscape.org/viewarticle/advancing-personalized-care-prostate-cancer-patient-centered-2025a1000uyb?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260220-OUS-HONC-advancing-personalized-care-prostate-cancer-patient-centered-2025a1000uyb-cta

Artistic expression, self-worth, and mental health: pathways to dignity Christopher Dowrick* [1]

https://www.academia.edu/2997-9196/2/4/10.20935/MHealthWellB7943 The perspective of this paper is that engagement with creative arts such as music, painting, and sculpture has the potential to enhance the dignity and self-respect of every person, especially those living with mental health problems. It may do so by enabling them to express and transform their experiences of distress and despair. Evidence is presented for the positive impact of artistic expression on mental health. The philosophical, biomedical, and psychological perspectives on the processes by which artistic engagement may enhance dignity are explained. Three examples are presented of the impact of creative arts on dignity and mental health: Joni Mitchell’s song ‘A Case of You’; Frida Kahlo’s painting The Broken Column; and Auguste Rodin’s sculpture The Burghers of Calais. The author shows how engagement with these artistic pieces has enhanced the self-worth, dignity, and mental health of three of his patients, facing psychological abuse, physical and emotional suffering, and imminent death. How values, commitment, and organizational climate shape job satisfaction and well-being Nicole Correia, Marina Carvalho Volume 3, Issue 1 https://www.academia.edu/journals/academia-mental-health-and-well-being/articles?source=journal-top-nav

Noise pollution and public health curricula: a missing link in environmental health preparedness Francesco Aletta* [1]

https://www.academia.edu/academia-global-and-public-health/1/1/10.20935/AcadPHealth8070 Environmental noise is a pervasive yet under-recognized public health hazard. Robust evidence links transport and community noise exposure to a range of adverse health outcomes, including sleep disturbance, cardiovascular disease, cognitive impairment, and reduced quality of life. Yet, despite its clear health burden, noise pollution remains marginal in global health agendas and is inconsistently integrated into education and training. Recent reforms to public health curricula, particularly in the United States, have contributed to a broader erosion of environmental health content, with noise largely absent or reduced to a subtopic within occupational health. This educational gap has significant implications: graduates often lack competencies in community exposure assessment, epidemiological interpretation, policy evaluation, and intersectoral interventions. Addressing the underrepresentation of noise in public health training is therefore a critical step toward mainstreaming noise as a determinant of health. Embedding core competencies on noise pollution in MPH curricula would enhance professional readiness, promote equity, and better align public health capacity with the scale of the problem. Malaria in childhood: school-based diagnosis and treatment as a public health approach offering equitable access to care Andrew Macnab Volume 2, Issue 1 https://www.academia.edu/journals/academia-global-and-public-health/articles?source=journal-top-nav

RARE Round-up - keeping you up-to-date

https://editions.rarerevolutionmagazine.com/html5/reader/production/default.aspx?pubname=&edid=5fddfc62-9dc6-47bf-aa6a-922d41bce312&pnum=76 Nadine Lipworth shares an all-too-familiar tale. She illustrates in real colour the true cost of inaction and the often untold trauma families face when confronted by that lack of action and an absence of a diagnosis. This is Nadine and her husband, Dave’s, journey so far while saving Sasha

Decades-old anti-seizure drug shows promise in preventing Alzheimer’s before it begins Researchers identify how levetiracetam keeps neurons from producing harmful amyloid-beta, pointing to new ways to intervene before Alzheimer’s symptoms appear.

https://www.drugdiscoverynews.com/decades-old-anti-seizure-drug-shows-promise-in-preventing-alzheimer-s-before-it-begins-17011

New epigenetic insights are accelerating drug discovery and clinical trials By tracking 5hmC in blood, researchers can capture active cancer pathways, identify novel drug targets, and monitor treatment response more efficiently than traditional approaches.

https://www.drugdiscoverynews.com/new-epigenetic-insights-are-accelerating-drug-discovery-and-clinical-trials-17010

The next wave of psychedelics focuses on brain rewiring without the trip By separating therapeutic neuroplasticity from hallucinations, new psychedelic-inspired molecules could make treatment safer and more accessible.

https://www.drugdiscoverynews.com/the-next-wave-of-psychedelics-focuses-on-brain-rewiring-without-the-trip-17014

Decoding the dark matter of the genome A new model combines high-resolution experimental data with deep learning to reveal how non-coding DNA sequences control gene activity across different cell types.

https://www.drugdiscoverynews.com/decoding-the-dark-matter-of-the-genome-17015

Weekly Rundown: Memory neurons split by protein output in first single-cell translation map of the brain Alzheimer's disease blood tests, FDA rejections, and more led the news this week.

https://www.drugdiscoverynews.com/weekly-rundown-memory-neurons-split-by-protein-output-in-first-single-cell-translation-map-of-the-brain-17018?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-_-kXaY_HziXmskV7xAIaQwKcTDrVmginEbV0rt8RgYXzNle5vHoqw1FHM7RamRtHyl6NboJaR4OshfcP-7XRRB3yG6bQ&_hsmi=404715041&utm_content=404715041&utm_source=hs_email

Virtual Patient Simulation for CLL: Test Your Skills Authors: Barbara F. Eichhorst, MD; Stephan Stilgenbauer, MD

https://www.medscape.org/viewarticle/virtual-patient-simulation-cll-test-your-skills-2025a1000wjp?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260220-OUS-HONC-virtual-patient-simulation-cll-test-your-skills-2025a1000wjp-cta

Medscape Now! Early-Onset Alzheimer Disease With a Genetic Cause: What Clinicians Need to Know Authors: CME Author: Blessing Ajayi, PA-C

https://www.medscape.org/viewarticle/medscape-now-early-onset-alzheimer-disease-genetic-cause-2026a1000556?page=1&sso=true&impID=8121382&uac=148436CN&src=wnl_tpal_260220_mscpedu

Challenges and Opportunities for CAR T-Cell Therapies to Treat Autoimmune Rheumatic Diseases Authors: Eric Morand, MD, PhD; David Simon, MHBA; Fabian Müller, MD; Gerhard Krönke, MD, MHBA

https://www.medscape.org/viewarticle/1003043?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260220-OUS-HONC-1003043-cta

Assessing Conditioning Regimens for HSCT: Optimizing Patient Outcomes Authors: Mohamad Mohty, MD, PhD; Daniele Avenoso, MD, PhD; Simona Sica, MD, PhD; Sergio Giralt, MD, FACP, FASTCT

https://www.medscape.org/viewarticle/1003061?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260221-OUS-HONC-1003061-cta

Editorial p115 The value of patient experience in multiple sclerosis research The Lancet Neurology ++ +... +...

A multimodal individualized long-term intervention to prevent functional decline after stroke (LAST-long): a single blinded randomised controlled trial Torunn Askima,b,j torunn.askim@ntnu.no ∙ Sara Rise Langloa,c,j ∙ Elin Bergha,d ∙ Øystein Døhla,e ∙ Hanne Ellekjæra,b ∙ Anne Hokstada,c ∙ et al. https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(25)00323-0/fulltext?dgcid=hubspot_email_infocusalerts-neurology_feature&utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz-9Hjh-_IXvEs33uN42o80pFeEkEGgQ7db8b5mSk-CU5WrUizkGjKzWzDiIdZhQhOWrax7wg30dPSQNmOJZ0YMHNRqFbug&_hsmi=404745008&utm_content=404691632&utm_source=hs_email Safety and efficacy of adjunct dexamethasone in adults with herpes simplex virus encephalitis in the UK (DexEnceph): a multicentre, observer-blind, randomised, phase 3, controlled trial Prof Tom Solomon, FMedSci, PhDa,b,c,d tsolomon@liverpool.ac.uk ∙ Cory Hooper, PhDd ∙ Ava Easton, PhDd,e ∙ Anna Rosala-Hallas, MScf ∙ Bethany Facer, MScg ∙ Perry Moore, PhDc ∙ et al. https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00454-5/fulltext?dgcid=hubspot_email_infocusalerts-neurology_feature&utm_campaign=infocusalerts-neurology&utm_medium=email&_hsenc=p2ANqtz-_KFnSEeh3zG2AYRY-WA_FU6yYDc8wxk38NS-V1eWa0KCw9psaUQ6Qx93K1rijACkNPstHvXWu8AHb2ePmX9dIwcIVTsA&_hsmi=404745008&utm_content=404691632&utm_source=hs_email Editorial p115 The value of patient experience in multiple sclerosis research The Lancet Neurology https://www.thelancet.com/journals/laneur/issue/vol25no2/PIIS1474-4422(26)X0002-3 Editorial A new path for assisted dying in Europe: France's middle way The Lancet Regional Health – Europe https://www.thelancet.com/journals/lanepe/issue/vol61nonull/PIIS2666-7762(25)X0012-0

How Indoor Air Quality Affects Respiratory Health in Winter and Summer +++

How Indoor Air Quality Affects Respiratory Health in Winter and Summer https://www.news-medical.net/health/How-Indoor-Air-Quality-Affects-Respiratory-Health-in-Winter-and-Summer.aspx From elevated winter levels of polycyclic aromatic hydrocarbons (PAHs) in schools to humidity-linked infection risk in older adults, this review reveals how seasonal changes in indoor air may influence respiratory health and what can be done to reduce the burden. The Role of the Gut Microbiome in Gastrointestinal Cancer Development This article explains how host–microbiome interactions contribute to gastrointestinal cancer risk through microbial genotoxins, metabolic signaling pathways, immune dysregulation, and tumor microenvironment remodeling in colorectal and gastric cancers. It synthesizes current evidence to show how dysbiosis, microbial metabolites, and pathogen-driven signaling alter epithelial integrity, inflammation, and therapeutic response. https://www.news-medical.net/health/The-Role-of-the-Gut-Microbiome-in-Gastrointestinal-Cancer-Development.aspx Why Are Respiratory Infections More Common in Winter? Why do respiratory viruses surge each winter? From cold air and indoor crowding to seasonal immune shifts and shifting RSV–influenza dynamics, the science reveals how winter creates the perfect storm for viral spread. https://www.news-medical.net/health/Why-Are-Respiratory-Infections-More-Common-in-Winter.aspx

Grip strength links to longer life in women over 60

https://www.news-medical.net/news/20260220/Grip-strength-links-to-longer-life-in-women-over-60.aspx A large, diverse cohort study shows that muscle strength, especially grip strength, may signal survival odds in older women, regardless of how much they move, how long they sit, or their measured fitness level.

Welcome to NIH 3D NIH 3D is an open, community-driven portal to download, share, and create bioscientific and medical 3D models for 3D printing

Welcome to NIH 3D NIH 3D is an open, community-driven portal to download, share, and create bioscientific and medical 3D models for 3D printing and interactive 3D visualization, including virtual and augmented reality. https://3d.nih.gov/ We’re pleased to share a major update to NIH 3D! The platform has been completely redesigned to improve performance and features an enhanced 3D viewer, AlphaFold integration, and more, while maintaining the familiar workflows you already use. What's New in NIH 3D Redesigned 3D viewer with new customization tools: • Adjust material colors to highlight specific structures. • Hide components to focus on regions of interest. • Apply transparency to reveal internal features. • Export models for downstream use. AlphaFold Database integration for quick 3D visualization of protein structure predictions. WebXR beta viewer for VR Meta Quest 2 or 3 headsets to explore 3D models from your browser. 3D rendering of a DNA double helix with glossy pink and blue gradient surface against a blue background

NF1-Associated Plexiform Neurofibromas in Adults: Which Patients Could Benefit From Emerging Systemic Therapies? Authors: Andrea Gross, MD; João Passos, MD

https://www.medscape.org/viewarticle/1003044?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260219-OUS-HONC-1003044-cta

Health on the front line: 4 years of war in Ukraine The Lancet ++... ++

Health on the front line: 4 years of war in Ukraine The Lancet https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00355-7/fulltext?dgcid=raven_jbs_etoc_email Feb 21, 2026 Volume 407Number 10530p733-824, e4-e5 https://www.thelancet.com/journals/lancet/issue/vol407no10530/PIIS0140-6736(26)X2005-0 Tenecteplase versus standard medical treatment for basilar artery occlusion within 24 h (TRACE-5): a multicentre, prospective, randomised, open-label, blinded-endpoint, superiority, phase 3 trial Prof Yunyun Xiong, MDa,g,* ∙ Fana Alemseged, MDb,* ∙ Zhixin Cao, MDa ∙ Prof Lee H Schwamm, MDc ∙ Si Zhang, BEngd ∙ Prof Mark W Parsons, PhDe ∙ et al. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)02633-9/abstract?dgcid=raven_jbs_etoc_feature_lancet Leprosy Prof Nelson Iván Agudelo Higuita, MDa,b nelson-agudelo-higuita@ou.edu ∙ Charlotte Avanzi, PhDc,d,e ∙ Andrés F Henao-Martínez, MDf ∙ Tanvi P Honap, PhDc,d,e ∙ Neema Bendera, MScg,h ∙ Carlos Franco-Paredes, MDc,i ∙ et al. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(25)01963-4/abstract?dgcid=raven_jbs_etoc_feature_lancet

Most Read Cancer Science & Oncogenesis +...

https://read.qxmd.com/collection/1133?ecd=wnl_readmost_260220

Heart Hacks For Your Health By Ivanhoe Broadcast News on February 23, 2026

https://www.ivanhoe.com/?p=36711&preview=1&_ppp=8d7a3b8e06 Orlando, Fla. (Ivanhoe Newswire) — February is National Heart Health Month. Do you know heart disease is the leading cause of death in the U.S. claiming more lives than cancer and accidental deaths combined! And a new Cleveland Clinic National Survey finds many Americans are unaware that everyday habits can quietly damage their heart increasing the risk of heart disease, heart attack, and stroke.

Beat The Feb Funk: Speak Smart To Your Kids By Ivanhoe Broadcast News on February 24, 2026

https://www.ivanhoe.com/?p=36714&preview=1&_ppp=ed2a6b3c69 Orlando, Fla. (Ivanhoe Newswire) — Teachers have a name for February — they call it “Slump Month.” Research shows this is when students’ motivation, mood, and even grades can dip mid-school year. The combination of cold, gray weather, a heavier academic load and no big breaks in sight can make even the most driven kids struggle. But there are ways to help them reset.

Helpful Or Harmful? The AI Effect On Kids By Ivanhoe Broadcast News on February 25, 2026

https://www.ivanhoe.com/?p=36717&preview=1&_ppp=a539bac1f3 Orlando, Fla. (Ivanhoe Newswire) — Artificial intelligence, or AI, is rapidly changing the world we live in. And now, it’s reaching kids and teens in ways many parents never expected. Surveys show one in five teens say they, or someone they know, has used AI for a romantic or emotional connection. So how do you help your child navigate a technology that can be both helpful and harmful?

Feeling FOBO? You’re Not Alone By Ivanhoe Broadcast News on February 26, 2026

https://www.ivanhoe.com/?p=36720&preview=1&_ppp=442d53a1ca Orlando, Fla. (Ivanhoe Newswire) — Artificial intelligence is changing more than how we work, it’s changing how we measure relevance. A growing number of adults are experiencing what experts call FOBO — Fear Of Becoming Obsolete — as new skills are expected almost overnight. New data shows skill demands in AI exposed jobs are changing 66 percent faster than they did last year, meaning what got you hired yesterday might not cut it tomorrow. But staying relevant isn’t about age or even technology — it’s about learning, connection, and adaptability.

The Parenting Trap: Why Kids Need Love And Limits By Ivanhoe Broadcast News on February 27, 2026

https://www.ivanhoe.com/?p=36723&preview=1&_ppp=44ac5ab863 Orlando, Fla. (Ivanhoe Newswire) — Every generation tries to reinvent the wheel and millennials are no different. From how they work to how they marry and how they raise their kids. New surveys show 88 percent of millennial parents say their parenting style is different from how they were raised and 73 percent believe it’s better. The latest approach is called gentle parenting, and three out of four millennials say they practice it. But experts say when gentle parenting goes too far, it can backfire.

Unexpected Survival Signal: Aprepitant Use During Chemotherapy Linked to Improved Breast Cancer Outcomes Maurie Markman, MD February 19, 2026

https://www.medscape.com/viewarticle/unexpected-survival-signal-aprepitant-use-during-2026a10002lz

Stereotactic Radiation Linked to Better Brain Mets Outcomes Edited by Katie Lennon February 20, 2026

https://www.medscape.com/viewarticle/stereotactic-radiation-linked-better-brain-mets-outcomes-2026a10005de

Pediatric Dermatology Admissions Drop, But Racial and Socioeconomic Disparities Persist Edited by Deepa Varma February 20, 2026

https://www.medscape.com/viewarticle/pediatric-dermatology-admissions-drop-racial-and-2026a10005cz

PSMA PET: Prostate Cancer Staging Revolution Awaits RCT Data M. Alexander Otto, PA, MMSc February 20, 2026

https://www.medscape.com/viewarticle/psma-pet-prostate-cancer-staging-revolution-awaits-rct-data-2026a10005d5

HER2 Therapy for Biliary Cancer Approved by UK Regulator Edited by Zeel Mehta Medscape UK February 20, 2026

https://www.medscape.com/viewarticle/her2-therapy-biliary-cancer-approved-uk-regulator-2026a10005eh

When a Breast Cancer Surgeon Gets Breast Cancer By Anne Peled, MD, and Ziv M. Peled, MD, as told to Anna Medaris February 20, 2026

https://www.medscape.com/viewarticle/when-breast-cancer-surgeon-gets-breast-cancer-2026a10005f6

Exercise May Improve Survival in a Variety of Cancer Types Megan Brooks February 20, 2026

https://www.medscape.com/viewarticle/exercise-may-improve-survival-variety-cancer-types-2026a10005ds

Pancreatic Cancer: Difficult Diagnosis, Ominous Outlook Roman Leonid Kleynberg, MD; Gennadiy (Henry) Guralnik; Katherine Pabon; Sean Ross Lazaro | February 11, 2026 |

https://reference.medscape.com/slideshow/pancreatic-cancer-6015119?ecd=wnl_critimg_260220_mscpref_etid8117243&uac=148436CN&impID=8117243 Pancreatic cancer remains a leading cause of death, with the American Cancer Society estimating 67,440 new cases and 51,980 deaths in 2025. While the average 5-year survival rate has risen to 13.3%, outcomes stay heavily dependent on the cancer’s stage at diagnosis.

FDA approves acalabrutinib with venetoclax for chronic lymphocytic leukemia or small lymphocytic lymphoma

https://www.fda.gov/drugs/resources-information-approved-drugs/fda-approves-acalabrutinib-venetoclax-chronic-lymphocytic-leukemia-or-small-lymphocytic-lymphoma?utm_medium=email&utm_source=govdelivery On February 19, 2026, the Food and Drug Administration approved acalabrutinib (Calquence, AstraZeneca) tablets and capsules in combination with venetoclax (Venclexta, AbbVie Inc. and Genentech Inc.) for adults with chronic lymphocytic leukemia (CLL) or small lymphocytic lymphoma (SLL).

FDA Moderna mRNA review flip-flop: A sledgehammer to vaccine—and a gift to anti-vaccine activists Henry Miller | February 19, 2026

https://geneticliteracyproject.org/2026/02/19/fda-moderna-mrna-review-flip-flop-a-sledgehammer-to-vaccine-and-a-gift-to-anti-vaccine-activists/

Manosphere social media influencers promote dangerous testosterone regimens Eurasia Review | February 18, 2026

https://geneticliteracyproject.org/2026/02/18/manosphere-social-media-influencers-promote-dangerous-testosterone-regimens/

AI regularly passes on misinformation because it relies more on the source than the science Nancy Lipid | Reuters | February 19, 2026

https://geneticliteracyproject.org/2026/02/19/ai-regularly-passes-on-misinformation-because-it-relies-more-on-the-source-than-the-science/

Vaccine rejectionist Jenny McCarthy ridiculed online after again spreading false claim that Tylenol causes autism Haley Gunn | Radar | February 19, 2026

https://geneticliteracyproject.org/2026/02/19/vaccine-rejectionist-jenny-mccarthy-ridiculed-online-after-again-spreading-false-claim-that-tylenol-calls-autism/

‘A chill through the entire vaccine industry’: RFK., Jr.’s flip-flop on Moderna’s mRNA vaccine latest setback Rebecca Robbins | New York Times | February 19, 2026

https://geneticliteracyproject.org/2026/02/19/a-chill-through-the-entire-vaccine-industry-rfk-jr-s-sidelining-modernas-mrna-vaccine-latest-setback/

Viewpoint: As gun laws weaken, deaths rise sharply Chuck Dinerstein | February 18, 2026

https://geneticliteracyproject.org/2026/02/18/viewpoint-as-gun-laws-weaken-deaths-rise-sharply/

I took part in a 2012 psilocybin trial. What I’m seeing now horrifies me For-profit companies are discarding central components of psychedelic therapy

https://www.statnews.com/2026/02/19/psychedelic-therapy-more-than-just-drugs/ By Erica RexFeb. 19, 2026 Rex is the author of the new book “Seeing What Is There: My Search for Sanity in the Psychedelic Era.”

What to expect from Gossamer Bio’s late-stage lung disease study Plus: ProMis Neurosciences takes its shot at a better, safer Alzheimer’s treatment By Adam FeuersteinFeb. 19, 2026 Senior Writer, Biotech

https://www.statnews.com/2026/02/19/gossamer-bio-promis-neurosciences/

My biggest GLP-1 ethical problem: patients who don’t want to stop We’ve gone from weight loss drug shortages to a problem of excess — and eating disorders

https://www.statnews.com/2026/02/19/glp-1-weight-loss-drugs-eating-disorders-doctor/ By Jody DushayFeb. 19, 2026 Dushay is an assistant professor of medicine at Harvard Medical School and an attending endocrinologist at Beth Israel Deaconess Medical Center.

Should semen analysis become the Pap smear for men? Some men’s health experts say yes Unusual sperm count or motility can flag risk of diseases as well as possible fertility problems

https://www.statnews.com/2026/02/19/semen-analysis-startups-pitch-male-version-pap-smear/ By Annalisa MerelliFeb. 19, 2026 Contributing Writer

How Palliative Care Helps People Living with Heart Failure

https://getpalliativecare.org/how-palliative-care-helps-with-chf2023/?utm_source=Get+Palliative+Care&utm_campaign=15603d38a5-GPC+-+Heart+Month+%2F+02.18.26&utm_medium=email&utm_term=0_4ef32a103e-15603d38a5-378264050

Endocrine Therapies in ER-Positive/HER2-Negative MBC: Understanding Their Benefits and Limitations to Optimize Treatment Selection Authors: Joyce A. O’Shaughnessy, MD; Aditya Bardia, MD, MPH, FASCO

https://www.medscape.org/viewarticle/1003008?sso=true&uac=148436CN&src=mkmcmr_driv_32025_mscpedu_437674.02_ace_launch

FDA Approves Monthly Dosing of Rybrevant Faspro for NSCLC Sharon Worcester February 18, 2026

https://www.medscape.com/viewarticle/fda-approves-monthly-dosing-rybrevant-faspro-nsclc-2026a1000570

Which Salvage Therapy Is Best for Recurrent Prostate Cancer? Frederik Joelving February 19, 2026

https://www.medscape.com/viewarticle/which-salvage-therapy-best-recurrent-prostate-cancer-2026a100058a

Amivantamab Linked to Diverse Dermatologic Adverse Events in Patients With Non-Small Cell Lung Cancer Edited by Vineeta Teotia Medscape UK February 19, 2026

https://www.medscape.com/viewarticle/amivantamab-linked-diverse-dermatologic-adverse-events-2026a10004zm

Fast Five Quiz: Oligometastatic Breast Cancer Reviewed by Maurie Markman, MD February 17, 2026

https://reference.medscape.com/viewarticle/oligometastatic-breast-cancer-2026a10000im?_gl=1*1iva6cp*_gcl_au*NjcyMzY3MDc5LjE3NjYwNjkxODQuMTExNjU3MzA1NS4xNzcxNTA3NDU3LjE3NzE1MDc5MDA.

Fast Five Quiz: Escalation and De-Escalation of Therapy in Early Breast Cancer Reviewed by Maurie Markman, MD February 17, 2026

https://reference.medscape.com/viewarticle/early-bc-de-escalation-and-escalation-therapy-2026a10000a4?_gl=1*3i69rg*_gcl_au*NjcyMzY3MDc5LjE3NjYwNjkxODQuMTExNjU3MzA1NS4xNzcxNTA3NDU3LjE3NzE1MDc5MDA.

Pediatric Low-Grade Glioma With BRAF Alterations: Stories, Science, and Strategies Authors: Darren Hargrave, MBChB, MD; Cameron Miller; Enrico Opocher, MD; Sébastien Perreault, MD, FRCPC

https://www.medscape.org/viewarticle/pediatric-low-grade-glioma-braf-alterations-stories-science-2025a1000x3w?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260218-OUS-HONC-pediatric-low-grade-glioma-braf-alterations-stories-science-2025a1000x3w-cta

Navigating Advances in TRK Fusion-Positive Cancers: A Collaborative Journey From Testing to Therapy Authors: David S. Hong, MD; Theodore W. Laetsch, MD; Jonathan C. Trent, MD, PhD

https://www.medscape.org/viewarticle/navigating-advances-trk-fusion-positive-cancers-2025a1000z5i?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260218-OUS-HONC-navigating-advances-trk-fusion-positive-cancers-2025a1000z5i-cta

Navigating the HER2 Spectrum in Breast Cancer: Evolving Diagnostic Paradigms for Clinical Excellence Authors: Sara M. Tolaney, MD, MPH; Frédérique Penault-Llorca, MD; Giuseppe Curigliano, MD, PhD

https://www.medscape.org/viewarticle/navigating-her2-spectrum-breast-cancer-evolving-diagnostic-2026a10004ea?page=1&sso=true&impID=8115993&uac=148436CN&src=wnl_tpal_260218_mscpedu

Conference Insights: Breaking Developments in ALK-Positive NSCLC and ES-SCLC Authors: Solange Peters, MD, PhD; Shirish M. Gadgeel, MD; Rafal Dziadziuszko, MD, PhD

https://www.medscape.org/viewarticle/conference-insights-breaking-developments-alk-positive-nsclc-2025a1000vwn?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260218-OUS-HONC-conference-insights-breaking-developments-alk-positive-nsclc-2025a1000vwn-cta

Oral weight loss ingredient may have adverse biological effects for the gut and beyond

https://www.news-medical.net/news/20260217/Oral-weight-loss-ingredient-may-have-adverse-biological-effects-for-the-gut-and-beyond.aspx A new study from Adelaide University is turning a spotlight on those tablet versions, finding that the absorption-enhancing ingredient salcaprozate sodium (SNAC) may have measurable adverse biological effects for the gut and beyond.

European report: Antimicrobial resistance remains widespread in foodborne bacteria

https://www.news-medical.net/news/20260218/European-report-Antimicrobial-resistance-remains-widespread-in-foodborne-bacteria.aspx Antimicrobial resistance (AMR) in common foodborne bacteria such as Salmonella and Campylobacter continues to be a public health concern across Europe, according to a new joint report from the European Food Safety Authority (EFSA) and the European Centre for Disease Prevention and Control (ECDC).

Researchers find new way to halt leukemia stem cell growth

https://www.news-medical.net/news/20260218/Researchers-find-new-way-to-halt-leukemia-stem-cell-growth.aspx In a new study published in Nature Communications, a research team at the University of Oslo have examined how cancer cells develop in the bone marrow and whether it might be possible to stop them. The study finds a way to stop malignant stem cells. The researchers believe their findings could open up new avenues for treatment in the future.

Diet and the Reprogramming of Innate Immune Memory

https://www.news-medical.net/health/Diet-and-the-Reprogramming-of-Innate-Immune-Memory.aspx Emerging research reveals how specific dietary components may reshape innate immune memory at the level of metabolism and chromatin, offering new insight into the biological interface between nutrition and immune resilience.

How Heat Stress Affects the Human Body at the Cellular Level

https://www.news-medical.net/health/How-Heat-Stress-Affects-the-Human-Body-at-the-Cellular-Level.aspx Rising temperatures disrupt human cellular stability by impairing proteostasis, altering mitochondrial function, reprogramming gene expression, and reshaping immune responses, ultimately shifting cells from adaptive survival toward inflammation and programmed death under sustained stress.

Ovarian Aging Explained: Biological Age, Fertility, and Epigenetic Markers

https://www.news-medical.net/health/Ovarian-Aging-Explained-Biological-Age-Fertility-and-Epigenetic-Markers.aspx Epigenetic clocks provide a molecular framework for assessing biological ovarian age by integrating DNA methylation patterns with hallmarks of reproductive aging. While these clocks show moderate predictive value for fertility outcomes such as IVF success, they currently function best as complementary research tools rather than standalone clinical diagnostics.

Can mobile apps change how we eat?

https://www.news-medical.net/news/20260218/Can-mobile-apps-change-how-we-eat.aspx From eco-score apps to immersive virtual supermarkets, researchers explore whether technology can nudge people toward healthier and more sustainable eating habits, and why stronger, longer-term evidence is still urgently needed.

Living rare: finding my voice with diffuse systemic scleroderma

https://rarerevolutionmagazine.com/living-rare-finding-my-voice-with-diffuse-systemic-scleroderma/ Kristina Hamilton is a patient advocate living with diffuse systemic scleroderma. Diagnosed in 2022, she shares her lived experience to raise awareness of rare and often misunderstood autoimmune diseases. Through storytelling and advocacy, Kristina is committed to helping others feel seen, less alone and empowered to use their voices within the rare disease community

Checkup Time! How Measurement Science Keeps You Healthy February 18, 2026 By: Riley Wilson

https://www.nist.gov/blogs/taking-measure/checkup-time-how-measurement-science-keeps-you-healthy

Toward dignity-centred ethics in the treatment of longstanding and severe eating disorders: a lived experience-led narrative review James Downs* [1] , Marissa Adams [2]

https://www.academia.edu/2997-9196/2/4/10.20935/MHealthWellB7942 Longstanding and severe eating disorders (LSEDs) are frequently marked by medical risk, therapeutic impasse, and exclusion from standard care pathways. Yet insufficient attention has been paid to the ethical dimensions of treatment for those with complex and longstanding illness trajectories, in particular from the perspective of those with lived experience. This paper aims to address this gap as a lived-experience-authored narrative review focused on the concept of dignity as a guiding value of ethical care in LSEDs. Informed by critical interpretive synthesis, narrative ethics, and reflective practice methods, the authors integrate multiple sources of evidence. They adopt a lens of epistemic injustice, situating subjective knowledge alongside empirical research findings and the wider conceptual and ethical considerations of treatment provision. The findings identify recurring patterns of undignified care in the treatment of LSEDs, including the normalisation of neglect, coercive practices, and exclusionary models of treatment. Principles and practical steps are outlined to inform dignity-affirming care, which include prioritising relational safety, co-produced decision-making, and re-medicalisation of LSEDs in ways that do not sacrifice autonomy. Ultimately, the authors determine that a dignity-centred approach to LSEDs requires a fundamental shift in how we understand risk, chronicity, and the place of lived experience in clinical ethics. This paper offers a conceptual and methodological framework to support that shift, calling for collective responsibility and structurally embedded forms of care that respect the knowledge, rights, and needs of those most affected by LSEDs.

To bring about a dramatic and wide reaching change in conditions and attitudes for the rare disease community.

https://rarerevolutionmagazine.com/

A new dawn for osteoporosis drug development The Lancet Diabetes & Endocrinology ++... ++

A new dawn for osteoporosis drug development The Lancet Diabetes & Endocrinology https://www.thelancet.com/journals/landia/article/PIIS2213-8587(26)00011-2/fulltext?dgcid=raven_jbs_etoc_email Mar 2026 Volume 14Number 3p187-274, e3-e6 https://www.thelancet.com/journals/landia/issue/vol14no3/PIIS2213-8587(26)X2001-0 Efficacy and safety of inclisiran in adolescents with heterozygous familial hypercholesterolaemia (ORION-16): a two-part, randomised, multicentre clinical trial Albert Wiegman, MD PhDa a.wiegman@amsterdamumc.nl ∙ Prof Amy L Peterson, MD MSb ∙ Prof Eric Bruckert, MDc ∙ Joep C Defesche, PhDd ∙ Anja Schweizer, PhDe ∙ Prof Jean Bergeron, MDf ∙ et al. https://www.thelancet.com/journals/landia/article/PIIS2213-8587(25)00351-1/abstract?dgcid=raven_jbs_etoc_feature_landia The Lancet Summit: shaping the future of diabetes prevention Nov 30–Dec 2, 2026 | Sitges, Spain https://thelancetsummit.com/diabetes-prevention/index.html

Precision Oncology in HER2-Mutated NSCLC: Strategies for Today and Tomorrow Authors: Yong Fang, MD; Hye Ryun Kim, MD, PhD; Hibiki Udagawa, MD, PhD

https://www.medscape.org/viewarticle/precision-oncology-her2-mutated-nsclc-strategies-today-and-2025a100105r?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260217-OUS-HONC-precision-oncology-her2-mutated-nsclc-strategies-today-and-2025a100105r-cta

Cut through the menopause noise with better benefits Wednesday, February 25, 2026 2:00 PM Eastern Standard Time 1 hour

https://event.on24.com/wcc/r/5194789/258ADAE15FF947CF2F31E1B312301E14?partnerref=HRDA-Textlogo

Optimizing Outcomes With Radiopharmaceuticals in mCRPC Care: From Evidence to Execution Authors: Joe O’Sullivan, PhD, MD, BAO, BCH, FRCR, FFRRCSI, FRCPI; Irene Burger, MD; Elena Castro, MD, PhD; Bertrand Tombal, MD, PhD

https://www.medscape.org/viewarticle/1003032?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260217-OUS-HONC-1003032-cta

RISE Together: Data Sharing Across the Rare Disease Ecosystem March 30, 2026 — 9:00AM–4:30PM

https://healthpolicy.duke.edu/events/rise-together-data-sharing-across-rare-disease-ecosystem?utm_medium=email&utm_source=govdelivery Registration is now open to attend the FDA Rare Disease Innovation Hub’s March 30th Rare Disease Innovation, Science, and Exploration (RISE) Workshop to explore data sharing as it pertains to informing development and regulatory review for rare disease therapies. This public workshop will focus on clarifying possible avenues for data sharing and the types of data that can be shared (e.g., safety information, real-world evidence, and deidentified patient data).The workshop will also discuss: the promotion of data sharing practices and structures for facilitating data sharing among rare disease drug development stakeholders; examples of the impact of data sharing in regulatory submissions; a priori considerations for the collection and sharing of high quality data; some of the logistical and legal challenges encountered in data sharing; and whether there are ways that FDA might support data sharing, within the bounds of its authority.

Gain a deeper knowledge of endocrine resistance mechanisms and treatment selection for ER-positive/HER2-negative metastatic breast cancer after progression

https://www.medscape.org/advances/oral-serds-2025a1000o90?sso=true&uac=148436CN&src=mkmcmr_driv_32025_mscpedu_437674.35_ace_launch ER-Positive/HER2-Negative Metastatic Breast Cancer: Navigating Endocrine Resistance and Expanding Treatment Options Endocrine therapy remains the cornerstone of treatment for ER-positive/HER2-negative metastatic breast cancer, yet both intrinsic and acquired resistance ultimately limit its long-term success. Resistance arises through diverse mechanisms—including activating ESR1 mutations, crosstalk with growth factor signaling pathways, and epigenetic changes—that allow tumor cells to bypass estrogen receptor blockade. New oral selective estrogen receptor degraders (SERDs) are designed to directly target and degrade the estrogen receptor, offering the potential to overcome ESR1-mediated resistance while providing the convenience of once-daily dosing. A deep understanding of endocrine resistance mechanisms is essential to identify which patients will derive the greatest benefit, to inform rational combination strategies, and ultimately to extend disease control and improve quality of life in this challenging clinical setting. This educational resource designed with the oncology team in mind, including oncologists, obstetrician/gynecologists, pathologists, nurse practitioners, nurses, and pharmacists, offers CME activities that feature insights from leading experts, along with engaging slide kits, clinical articles, and links to valuable resources. Together, these materials create a dynamic community of learning focused on enhancing patient care and achieving positive outcomes.

Public Meeting: FDA Rare Disease Day 2026 February 23, 2026

https://www.fda.gov/news-events/fda-meetings-conferences-and-workshops/public-meeting-fda-rare-disease-day-2026-02232026?utm_medium=email&utm_source=govdelivery FDA is hosting a virtual public meeting on February 23rd in observance of Rare Disease Day. We encourage you to participate and help advance rare disease treatment by sharing your treatment experiences. As this important day approaches, we invite you to contribute to CURE ID. Developed by FDA and NIH, CURE ID is a free platform where patients, caregivers, and clinicians can report their experiences using existing drugs in new ways to treat rare diseases. Approved reports are displayed to the public, once personal details have been removed from the data. This enables the community to contribute to a public database that may help identify new treatment options. Help find treatments for challenging diseases CURE ID is a free platform to share novel uses of existing drugs and explore what others have tried. The goal is to identify potential treatments for diseases without good treatment options. https://cure.ncats.io/home?utm_medium=email&utm_source=govdelivery

Health Literacy and HIV: Understanding the Tools in the HIV Prevention Toolbox

https://www.hiv.gov/blog/health-literacy-and-hiv-understanding-the-tools-in-the-hiv-prevention-toolbox?j=2895435&sfmc_sub=6992026&l=6498_HTML&u=71999665&mid=100006181&jb=0 Increasing health literacy is something we should promote year round, including health literacy about HIV prevention. When we work to increase people’s health literacy about HIV prevention by empowering them with information, they can take charge of their health. Our latest blog post does this by making the tools in the HIV prevention toolbox easy to understand and accessible.

Communicating to Enhance Care Through Data and Patient Experience: ER-Positive/HER2-Negative Metastatic Breast Cancer Edition Authors: Kelly Shanahan, MD; Sara Tolaney, MD, MPH; Virginia Kaklamani, MD, DSc; Sarah R. Donahue, MPH, NP, AOCNP; Abigail Shockley, PharmD, BCOP

https://www.medscape.org/viewarticle/communicating-enhance-care-through-data-and-patient-2025a1000uqi?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260217-OUS-HONC-communicating-enhance-care-through-data-and-patient-2025a1000uqi-cta

Beyond the Infusion Chair: Expanding the Repertoire With Subcutaneous Immunotherapy in Cancer Care Authors: Laurence Albiges, MD, PhD; Maria T. Bourlon, MD, MS; Antonella Cardone

https://www.medscape.org/viewarticle/beyond-infusion-chair-expanding-repertoire-subcutaneous-2025a1000y59?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_cust_mscpedu_260218-LATAM-HONC-beyond-infusion-chair-expanding-repertoire-subcutaneous-2025a1000y59-cta

Swallowing development in infants and toddlers with spinal muscular atrophy following therapy compared to healthy controls: the prospective controlled DySMA trial Jana ZangCharlotte DumitrascuJessika Johannsen

https://link.springer.com/journal/13023?utm_source=bmc_etoc&utm_medium=email&utm_campaign=CONR_13023_AWA1_GL_DTEC_054CI_TOC-260214

Post-Traumatic Stress Disorder and Alcohol Consumption: Biological Mechanisms of Stress Resilience to Subsequent Alcohol Consumption Quilla C. Flanagan-Burt,* Celia Middleton,* and Junghyup Suh

https://arcr.niaaa.nih.gov/volume/46/1/post-traumatic-stress-disorder-and-alcohol-consumption-biological-mechanisms-stress?utm_source=arcr-email&utm_medium=email&utm_campaign=suh-2026-02&utm_content=arcr-listserv PURPOSE: Resilience is crucial in mitigating the risk of stress-related health issues. Although many people can adapt to adverse stress or trauma, stress exposure can increase the risk of health issues, including obesity, cardiovascular disease, and digestive illnesses. Some individuals may even develop debilitating conditions, such as post-traumatic stress disorder (PTSD). People with PTSD often struggle to adapt, sometimes turning to alcohol to cope, which can lead to alcohol use disorder (AUD), characterized by excessive alcohol-seeking and dependence. Understanding the biological underpinnings of resilience, therefore, is a key to preventing both PTSD and AUD. Recent research has uncovered the neurobiological traits that protect against the development of stress-induced alcohol dependence. Studies have shown that proactive coping and a lack of stress-related symptoms are associated with resilience. Preclinical studies, especially in rodents, have provided deeper insights into how stress impacts alcohol-seeking behaviors. Research has shown that resilience involves adaptive changes at the molecular, cellular, neural circuit, and systems levels. This review aims to integrate this research to better understand what makes people vulnerable to stress and alcohol consumption, highlighting aspects frequently overlooked in clinical models.

Introducing the CAHPS End-of-Life Care Survey (Webcast) January 15, 2026

https://www.ahrq.gov/cahps/news-and-events/events/webinar-end-of-life-survey-011526.html This webcast explored the purpose and development of AHRQ’s newest Consumer Assessment of Healthcare Providers and Systems (CAHPS®) End-of-Life Care Survey. Experts discussed why this new survey was created, how it was tested, and the best practices for its implementation. The session also featured insights from Kaiser Permanente, highlighting the organization’s experience using the survey during its field-testing phase. Speakers: Jonathan Bakdash, Ph.D., Agency for Healthcare Research and Quality Rebecca Anhang-Price, Ph.D., RAND Melissa Bradley, RAND Susan Wang, MD, Kaiser Permanente Stephanie Fry, CPXP, (Moderator), Westat https://www.ahrq.gov/cahps/surveys-guidance/end-of-life/index.html

Expanded Access to Investigational Drugs for Treatment Use - Questions and Answers April 15, 2026 | 1:00 PM - 2:30 PM ET

Expanded Access to Investigational Drugs for Treatment Use - Questions and Answers April 15, 2026 https://www.fda.gov/drugs/news-events-human-drugs/expanded-access-investigational-drugs-treatment-use-questions-and-answers-04152026?utm_medium=email&utm_source=govdelivery Join the Small Business and Industry Assistance (SBIA) program for an informative webinar on the guidance, Expanded Access to Investigational Drugs for Treatment Use: Questions and Answers. Expanded access is a pathway for patients with serious or immediately life-threatening diseases or conditions to gain access to investigational drugs for treatment outside of clinical trials when no comparable or satisfactory alternative treatment options are available. The primary goal of this event is to provide attendees with a comprehensive understanding of this pathway, including the regulatory requirements and FDA’s recommendations. The session will detail the three categories of Expanded Access (EA): individual patient, intermediate-size population, and treatment INDs and protocols, and will increase participants’ understanding of the criteria, submission requirements, and responsibilities of all parties involved. Expanded Access to Investigational Drugs for Treatment Use: Questions and Answers October 2025 https://www.fda.gov/regulatory-information/search-fda-guidance-documents/expanded-access-investigational-drugs-treatment-use-questions-and-answers-0?utm_medium=email&utm_source=govdelivery

What happens to large pieces of plastic as it breaks down in the ocean? Kate Spencer, Nan Wu | February 11, 2026

https://geneticliteracyproject.org/2026/02/11/what-happens-to-large-pieces-of-plastic-as-it-breaks-down-in-the-ocean/?mc_cid=f28fbdc5b1&mc_eid=b73600b7ac

A Look at Insect Cell Expression for Viral Vector and Virus-Like Particle Production

https://www.pharmasalmanac.com/articles/a-look-at-insect-cell-expression-for-viral-vector-and-virus-like-particle-production

Editing Risk: Gene Targets for Lifelong Cardiovascular Disease Prevention

https://www.pharmasalmanac.com/articles/editing-risk-gene-targets-for-lifelong-cardiovascular-disease-prevention

Revolutionizing Cell Culture Bioprocesses with Real-Time Glucose Measurement

https://www.pharmasalmanac.com/articles/revolutionizing-cell-culture-bioprocesses-with-real-time-glucose-measurement

Scarcity by Design: The Manufacturing Reality of AAV Gene Therapies for Rare Indications

https://www.pharmasalmanac.com/articles/scarcity-by-design-the-manufacturing-reality-of-aav-gene-therapies-for-rare-indications

A new path for assisted dying in Europe: France's middle way The Lancet Regional Health – Europe ++ ++...

Effectiveness of an environmental nutrition and physical activity intervention in early childhood education and care settings (NAPSACC UK): a multicentre cluster randomised controlled trial Ruth Kippinga ruth.kipping@bristol.ac.uk ∙ Sharon Anne Simpsonb ∙ Kim Hannama ∙ Peter S. Blaira ∙ Russell Jagoa ∙ Corby K. Martinc ∙ et al. https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(25)00342-4/fulltext?dgcid=hubspot_update_feature_updatealerts_lanepe&utm_campaign=update-lanepe&utm_medium=email&_hsenc=p2ANqtz--4YhCEdNZwP-0U8QNPvF_EznZOCHShSdVDTp8yp2wnznk190DfzStGA3jUwmLv6-9sAet6xn2H2rjBCY0hYSvqpA6sTQ&_hsmi=403964996&utm_content=403598960&utm_source=hs_email A multimodal individualized long-term intervention to prevent functional decline after stroke (LAST-long): a single blinded randomised controlled trial Torunn Askima,b,j torunn.askim@ntnu.no ∙ Sara Rise Langloa,c,j ∙ Elin Bergha,d ∙ Øystein Døhla,e ∙ Hanne Ellekjæra,b ∙ Anne Hokstada,c ∙ et al. https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(25)00323-0/fulltext?dgcid=hubspot_update_feature_updatealerts_lanepe&utm_campaign=update-lanepe&utm_medium=email&_hsenc=p2ANqtz-9YaOmCpScK-79DIiMVifSCYJJ3QxYaQssUoJQNjcAKC0PGgw2AMWA37KxkIVHKkKpglDbH5R8KjQahgxA-2umK3t7gYg&_hsmi=403964996&utm_content=403598960&utm_source=hs_email A new path for assisted dying in Europe: France's middle way The Lancet Regional Health – Europe https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(26)00029-3/fulltext?dgcid=hubspot_update_feature_updatealerts_lanepe&utm_campaign=update-lanepe&utm_medium=email&_hsenc=p2ANqtz--wsNlVf4WPY7SmYU3HWiScR6uCOfO1BfRc-_NhgaFD2j0Ao5qMWZH_m-gB-ETxkkOQelXYFgbEcVGwNus-37tsnR0H1Q&_hsmi=403964996&utm_content=403598960&utm_source=hs_email Feb 2026 Volume 61 https://www.thelancet.com/journals/lanepe/issue/vol61nonull/PIIS2666-7762(25)X0012-0

Editorial p99 Lifting the veil on tobacco industry influence The Lancet Respiratory Medicine +++ +...

Oral corticosteroid reduction and discontinuation in adults with corticosteroid-dependent, severe, uncontrolled asthma treated with tezepelumab (WAYFINDER): a multicentre, single-arm, phase 3b trial Prof David J Jackson, FRCPa david.jackson47@nhs.net ∙ Prof Njira L Lugogo, MDb ∙ Prof Mark Gurnell, PhDc,d ∙ Prof Liam G Heaney, MDe ∙ Prof Stephanie Korn, MDf,g ∙ Prof Guy Brusselle, MDh ∙ et al. https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00359-5/fulltext?dgcid=hubspot_update_feature_updatealerts_lanres&utm_campaign=update-lanres&utm_medium=email&_hsenc=p2ANqtz-8WDqTrpJQhwPRA-h3mmwGaFzc18kP9uiQXYFW8EPg5NjH_8uQXTGqEdIFvvumDz7iDD1-72EZdwqn67W1puLcE-Er_ew&_hsmi=403947918&utm_content=403597881&utm_source=hs_email Hospital and long-term outcomes for subglottic suction and polyurethane cuff versus standard endotracheal tubes in emergency intubation (PreVent 2): a randomised controlled phase 2 trial Prof Miriam M Treggiari, MD PhDa,c miriam.treggiari@duke.edu ∙ Emily S Sharp, PhDc ∙ Tetsu Ohnuma, MD PhDa ∙ Elaine C Fajardo, MDd ∙ Ani Aydin, MDe ∙ Prof Shamsuddin Akhtar, MDf ∙ et al. https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00294-2/abstract?utm_campaign=update-lanres&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanres&_hsenc=p2ANqtz-_z21Zfw2SBGyyQ2y9s6XukT1sJLsLxE5T_GSvGmdy7w58Z8bwW-vn7X8AWzl0GO_7Werdeh2hU1qEdr647B2XTbRkbqw&_hsmi=403947918&utm_content=403597881&utm_source=hs_email Glecirasib plus sitneprotafib in patients with KRASG12C-mutated non-small-cell lung cancer in China: an open-label, multicentre, single-arm, phase 1/2a trial Jia Zhong, MDa,* ∙ Prof Jun Zhao, MDb,* ∙ Prof Jianchun Duan, MDa,c,* ∙ Prof Jian Fang, MDd ∙ Kailun Fei, MDa ∙ Xiaoyan Li, MDe ∙ et al. https://www.thelancet.com/journals/lanres/article/PIIS2213-2600(25)00258-9/abstract?utm_campaign=update-lanres&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanres&_hsenc=p2ANqtz--6ZFJHJu2e9QTx2-cCcHo0QFzLkMaVsmv-vio7DUcqU_hRN1Vii8jHl1b096ZX5niiDDcGR736WyHUQD83sdcM75CYIA&_hsmi=403947918&utm_content=403597881&utm_source=hs_email Editorial p99 Lifting the veil on tobacco industry influence The Lancet Respiratory Medicine https://www.thelancet.com/journals/lanres/issue/vol14no2/PIIS2213-2600(26)X2001-X

Safeguarding women and girls in the age of AI The Lancet Global Health ++... ++

Safeguarding women and girls in the age of AI The Lancet Global Health https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(26)00030-6/fulltext?dgcid=raven_jbs_etoc_email Mar 2026 Volume 14Number 3e311-e474 https://www.thelancet.com/journals/langlo/issue/vol14no3/PIIS2214-109X(26)X2001-0 Avoidable deaths through the primary prevention, early detection, and curative treatment of cancer worldwide: a population-based study Oliver Langselius, PhDa,b,c,* langseliuso@iarc.who.int ∙ Harriet Rumgay, PhDa,* ∙ Jérôme Vignat, MSca ∙ Hadrien Charvat, PhDa ∙ Mark J Rutherford, PhDa,d ∙ Allini Mafra, PhDe ∙ et al. https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(25)00494-2/fulltext?dgcid=raven_jbs_etoc_feature_langlo Effective cataract surgical coverage in adults aged 50 years and older: empirical estimates from population-based surveys in 68 countries and modelled estimates for 2000–30 Ian McCormick, PhDa ian.mccormick@lshtm.ac.uk ∙ Yamna Ouchtar, PhDb ∙ David Macleod, PhDb ∙ Anna Harte, PhDc ∙ Maria Vittoria Cicinelli, MDd ∙ Tabassom Sedighi, PhDe ∙ et al https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(25)00435-8/fulltext?dgcid=raven_jbs_etoc_feature_langlo

Join us for Webinar on Addressing Veteran Substance Use: Promoting Recovery Through Collaboration and Compassion March 3, 2–3:30 p.m. ET

https://prainc.zoom.us/webinar/register/WN_ez-Bdfv3QTGgOxpvuFUtCw?utm_source=SAMHSA&utm_campaign=a8e747a6f3-EMAIL_CAMPAIGN_2026_01_26_02_20_COPY_01&utm_medium=email&utm_term=0_-b17f140eb4-167840245#/registration Supporting Veterans means strengthening recovery pathways. Attend this free webinar and learn how cross-system collaboration improves outcomes in substance use care. Join leaders from the Department of Veterans Affairs, SAFE Project, and Oregon Health Authority leaders for a focused discussion on effective, evidence-informed approaches to supporting Veterans and Service Members affected by substance use. Key learning objectives: Key trends in Veteran substance use and co-occurring conditions  Proven treatment and recovery models Practical strategies for cross-system collaboration Featured Speakers: Jay A. Gorman, Ph.D., Department of Veterans Affairs  Adam Swift, SAFE Project  Susan Davis, LPC, CADC I, Oregon Health Authority  This webinar will be followed by a learning community series exploring each of these topics in greater detail. If you are interested, you can get further information via our monthly newsletter or from our SMVF TA Upcoming Events. 

Global Health in Transition as Chronic Diseases Rise Massimo Sandal Medscape Europe February 17, 2026

https://www.medscape.com/viewarticle/global-health-transition-chronic-diseases-rise-2026a10004yg

Stick a Fork in Aspirin for Cancer Prevention in Over-70s Will Pass February 17, 2026

https://www.medscape.com/viewarticle/stick-fork-aspirin-cancer-prevention-older-adults-2026a10004yn

Ocular’s experimental eye drug beats low dose of Regeneron’s Eylea in late-stage trial Biotech firm aims to win FDA approval based on study’s results

https://www.statnews.com/2026/02/17/ocular-therapeutix-axpaxli-wet-amd-treatment-compared-to-eylea-regeneron/ By Adam FeuersteinFeb. 17, 2026 Adam Feuerstein, a senior writer and biotech columnist, is the author of Adam’s Biotech Scorecard, a subscriber-only newsletter about the crossroads of drug development, business, Wall Street, and biotechnology.

Editorial p137 Cancer: another casualty of geopolitical unrest? The Lancet Oncology +++ +...

Aumolertinib as adjuvant therapy in resected EGFR-mutated non-small-cell lung cancer (ARTS): a double-blind, multicentre, randomised, controlled, phase 3 trial Liang Zhang, MDa ∙ Xiqin Zhang, BSb ∙ Lin Wu, MDc ∙ Wenqun Xing, BSd ∙ Chunling Liu, MSe ∙ Prof Peng Zhang, MDf ∙ et al. https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(25)00643-6/abstract?utm_campaign=update-lanonc&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanonc&_hsenc=p2ANqtz-9HfIlNZWEKCqhm6q6IY9r4FCJ7kgJprjNHTTJ0sy5IryHglgZ6i5oWbafz9c-4Tdatg8Wpigj0aXUKuF-7NzUYoHC3-w&_hsmi=403942809&utm_content=403597534&utm_source=hs_email Expert recommendations for the conduct and appraisal of qualitative research in oncology Erica C Kaye, MDa,* erica.kaye@stjude.org ∙ Jori Bogetz, MDd,e,* ∙ Krysta S Barton, PhDf ∙ Cynthia J Bell, PhDg ∙ Emily E Johnston, MDh,i ∙ Rachel A Pozzar, PhDj ∙ et al. https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(25)00670-9/abstract?utm_campaign=update-lanonc&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanonc&_hsenc=p2ANqtz-_Kk6IiatuW32C9-VEm3Ut1uvzC5wAOq5c43xD9SNoOj5LE193z8t1-mOZRZZPgFtmx-ibwOua4rSkAQ8kmJWw8JpHmzg&_hsmi=403942809&utm_content=403597534&utm_source=hs_email Radiotherapy has a role to play in patients with EGFR-mutated non-small-cell lung cancer in first-line treatment Dirk De Ruysscher ∙ Pim J J Damen p.damen@erasmusmc.nl ∙ Lizza E L Hendriks lizza.hendriks@mumc.nl ∙ Stephanie P L Saw https://www.thelancet.com/journals/lanonc/article/PIIS1470-2045(25)00756-9/abstract?utm_campaign=update-lanonc&utm_medium=email&dgcid=hubspot_update_feature_updatealerts_lanonc&_hsenc=p2ANqtz-80oGo9Ar3KkITkJW6JZX5vnE_6ECt0OxfpQJsyOssMMWV0oohxODo-pd064x0jNIDFtu8Wsh8L72w-pLEA0Il0OjLQcw&_hsmi=403942809&utm_content=403597534&utm_source=hs_email Editorial p137 Cancer: another casualty of geopolitical unrest? The Lancet Oncology https://www.thelancet.com/journals/lanonc/issue/vol27no2/PIIS1470-2045(26)X2001-0

Challenges and Opportunities for CAR T-Cell Therapies to Treat Autoimmune Rheumatic Diseases Authors: Eric Morand, MD, PhD; David Simon, MHBA; Fabian Müller, MD; Gerhard Krönke, MD, MHBA

https://www.medscape.org/viewarticle/1003043?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260216-OUS-HONC-1003043-cta

Mastering Oral Therapies in CLL and MCL: Essential Strategies and Insights for Nurses Authors: Amy L. Goodrich, RN, MSN, CRNP-AC; Claudia Boglione, RN; Natacha Bolanos

https://www.medscape.org/viewarticle/mastering-oral-therapies-cll-and-mcl-essential-strategies-2025a1000xko?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260216-OUS-HONC-mastering-oral-therapies-cll-and-mcl-essential-strategies-2025a1000xko-cta

Improving mCRPC Outcomes Using Radiopharmaceuticals: Evidence to Implementation Authors: Rana R. McKay, MD, FASCO; Matthew R. Cooperberg, MD, MPH; Sean M. McBride, MD, MPH, MS

https://www.medscape.org/viewarticle/1003039?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260217-OUS-HONC-1003039-cta

Can parasites influence insulin signaling and development of diabetes mellitus? Gumpeny Ramachandra Sridhar* [1] , Srinivas Botta [2] , Gumpeny Lakshmi [3] ++...

https://www.academia.edu/2837-4010/4/1/10.20935/AcadBiol8088 While type 2 diabetes mellitus (T2DM) is a global health challenge, parasitic infections are prevalent in tropical and subtropical regions. There is evidence of a complex relationship between schistosomiasis and T2DM, implicating helminth infections as potential modulators of diabetes and metabolic syndrome. It was observed that individuals with a history of schistosomiasis had lower prevalence of diabetes, insulin resistance, and metabolic syndrome. Mechanistic explanations suggest that helminths modulate host immunity, skewing responses towards an anti-inflammatory phenotype (Th2 cytokine dominance) and promoting regulatory macrophage populations (M2-like phenotype). Such immune modulation may prevent inflammation-driven insulin resistance, a hallmark of T2DM. Additionally, helminth infections influence host lipid metabolism and gut microbiota, both crucial for metabolic regulation. Despite largely protective findings, some reports present contrasting associations, underscoring the complexity of helminth–host metabolic interactions. Current research is focused on harnessing helminth-derived immunomodulatory molecules and excretory–secretory products as novel therapeutic agents for metabolic diseases. Clinical trials using controlled helminth infections have shown preliminary metabolic benefits, though significant clinical, cultural, and regulatory barriers remain. Overall, elucidating the intricate interplay between helminthic infections and T2DM opens promising therapeutic avenues, potentially redefining approaches for preventing and managing metabolic diseases. The need for echocardiographic reference values in adults over 80 years of age Miguel Quintana, Mira Carling, Anders Olofsson, Dag Isaksson, Jenny Fahlen, Elin Kärrman, Fredrik Pihl, Roland Forsberg, Björn Persson, Alen Lovric, Thomas Gustafsson, Karin Bouma Volume 4, Issue 1 https://www.academia.edu/journals/academia-biology/articles?source=journal-top-nav

Gyrate atrophy of the choroid and retina: a tertiary center experience Ekin Özsaydı AktaşoğluHüseyin Baran ÖzdemirLeyla Tümer

https://link.springer.com/journal/13023?utm_source=bmc_etoc&utm_medium=email&utm_campaign=CONR_13023_AWA1_GL_DTEC_054CI_TOC-260215

GLP-1 drugs in haematology: beyond weight loss The Lancet Haematology + +...

GLP-1 drugs in haematology: beyond weight loss The Lancet Haematology https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(26)00002-5/fulltext?dgcid=hubspot_update_feature_updatealerts_lanhae&utm_campaign=update-lanhae&utm_medium=email&_hsenc=p2ANqtz--JBgPfmSamPIENTFgWS6pqIxvOW_SnhPv5bxv_TV-eYyU3NeY8ierOsQhFbPIxh7DNdx9FMwnjIyMbrlm4-6vM5wwPaQ&_hsmi=403816799&utm_content=403596743&utm_source=hs_email Glucagon-like peptide-1 receptor agonists (GLP-1RAs) began as therapies for type 2 diabetes but have become a breakthrough therapy for obesity, redefining its treatment and broader metabolic landscape. They have lit up medicine, popular culture, and global markets as new benefits and controversies unfold, with no field of medicine immune. By mimicking GLP-1 physiology, these drugs have come a long way, from the US Food and Drug Administration approval to treat type 2 diabetes in 2005 to approval to treat obesity in 2014, peaking with the 2021 subcutaneous weekly semaglutide regimen that delivered unprecedented weight loss. The excitement has only grown as trials reveal benefits in people with cardiovascular disease and sleep apnoea, and as emerging data hint at benefits in metabolic-dysfunction-associated liver disease, chronic kidney disease, peripheral artery disease, and osteoarthritis. In light of this growing evidence, it is reasonable to ask whether these agents could have an effect on haematological conditions. Feb 2026 Volume 13Number 2e55-e118 https://www.thelancet.com/journals/lanhae/issue/vol13no2/PIIS2352-3026(26)X2001-4

RARE Revolution RARE Bite

https://editions.rarerevolutionmagazine.com/html5/reader/production/default.aspx?pubname=&edid=5fddfc62-9dc6-47bf-aa6a-922d41bce312&pnum=76 Nadine Lipworth shares an all-too-familiar tale. She illustrates in real colour the true cost of inaction and the often untold trauma families face when confronted by that lack of action and an absence of a diagnosis. This is Nadine and her husband, Dave’s, journey so far while saving Sasha.

Nabil Seidah: The Discovery That Led to PCSK9 Cholesterol Therapies Islam Elkholi, MD,PHD February 16, 2026

https://www.medscape.com/viewarticle/nabil-seidah-discovery-led-pcsk9-cholesterol-therapies-2026a10004uk

Adding Protein EpiScores May Better Predict CRC Survival Will Pass February 16, 2026

https://www.medscape.com/viewarticle/adding-protein-episcores-may-better-predict-crc-survival-2026a10004s2

Skin-Related QOL in Chronic GVHD: Comparable With or Worse Than Dermatomyositis, Lupus Edited by Deepa Varma February 16, 2026

https://www.medscape.com/viewarticle/skin-related-qol-chronic-gvhd-comparable-or-worse-than-2026a10004rw

NSCLC Survival Not Tied to Common Drugs + Immunotherapy Use Edited by Gargi Mukherjee February 16, 2026

https://www.medscape.com/viewarticle/nsclc-survival-not-tied-common-drugs-immunotherapy-use-2026a10004sj

Acanthosis Nigricans With Germline EGFR L858R Variant Responds to Targeted Therapy John Jesitus February 16, 2026

https://www.medscape.com/viewarticle/acanthosis-nigricans-germline-egfr-l858r-variant-responds-2026a10004ui

Machine learning model demonstrates insulin resistance as a risk factor for 12 types of cancer

https://www.news-medical.net/news/20260216/Machine-learning-model-demonstrates-insulin-resistance-as-a-risk-factor-for-12-types-of-cancer.aspx Insulin resistance - when the body doesn't properly respond to insulin, a hormone that helps control blood glucose levels - is one of the fundamental causes of diabetes. In addition to diabetes, it is widely known that insulin resistance can lead to cardiovascular, kidney and liver diseases. While insulin resistance is tightly associated with obesity, it has been difficult to evaluate insulin resistance itself in the clinic. For the first time, researchers including those from the University of Tokyo applied a machine learning-based prediction model of insulin resistance to half a million participants from the UK Biobank and demonstrated that insulin resistance is a risk factor for 12 types of cancer.

Optimization of CAR T cells to destroy solid tumors

https://www.news-medical.net/news/20260216/Optimization-of-CAR-T-cells-to-destroy-solid-tumors.aspx A team led by LMU physician Sebastian Kobold has found a way to allow the body's immune system to destroy solid tumors.

Unlocking the potential of phytochemicals in rheumatoid arthritis treatment

https://www.news-medical.net/news/20260216/Unlocking-the-potential-of-phytochemicals-in-rheumatoid-arthritis-treatment.aspx Announcing a new article publication for BIO Integration journal. In recent years, phytochemicals and medicinal plants have increasingly been used to treat autoimmune diseases, such as rheumatoid arthritis (RA). RA, a systemic inflammatory disease, is a chronic condition that affects primarily the joints, which are lined by synovial membranes, and leads to pain, diminished mobility, and joint deterioration.

Diet and the Reprogramming of Innate Immune Memory

https://www.news-medical.net/health/Diet-and-the-Reprogramming-of-Innate-Immune-Memory.aspx Emerging research reveals how specific dietary components may reshape innate immune memory at the level of metabolism and chromatin, offering new insight into the biological interface between nutrition and immune resilience.

Eating more plant-based foods may lower breast cancer risk, major international study indicates

https://www.news-medical.net/news/20260215/Eating-more-plant-based-foods-may-lower-breast-cancer-risk-major-international-study-indicates.aspx Large international cohort data suggest plant-forward eating patterns and certain micronutrients may be linked to lower breast cancer risk and improved survival, highlighting diet as a potentially modifiable factor worth further investigation.

Experimental stem cell therapy aims to repair brain circuits in Parkinson’s A Phase 1 trial at Keck Medicine of USC is testing whether implanted iPSC-derived neurons can restore dopamine signaling and improve motor function.

https://www.drugdiscoverynews.com/experimental-stem-cell-therapy-aims-to-repair-brain-circuits-in-parkinson-s-17009 Parkinson’s disease (PD) is the fastest-growing neurodegenerative disorder worldwide, affecting an estimated one percent of individuals over the age of 60. In the US, more than one million people live with the disease, and roughly 90,000 new cases are diagnosed each year.

Expert-Driven, Patient-Focused: Mastering Personalized Care for HER2-Low Metastatic Breast Cancer Authors: Kevin Kalinsky, MD, MS, FASCO +++

https://www.medscape.org/viewarticle/1002880?sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260215-OUS-HONC-1002880-cta Keyboard typing test could help diagnose Parkinson’s disease early New software and hardware tools that collect data while a person types can detect fine motor impairment — a possible sign of neurodegeneration. https://www.drugdiscoverynews.com/keyboard-typing-test-could-help-diagnose-parkinson-s-disease-early-16713?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-9jRV2zkFBGFtv7ZuNtKvBMnqlRdAAhsAITRI_X8Yff65KpDf0dcuQ1BKQ5-lQAtlnGZW2srRGlVE7phxe4aeDKL39jTQ&_hsmi=403918635&utm_content=403918635&utm_source=hs_email A new Parkinson’s disease treatment that adapts to the brain The FDA approved Medtronic’s adaptive deep brain stimulation system, which delivers electrical stimulation in real time based on the brain’s state. https://www.drugdiscoverynews.com/a-new-parkinson-s-disease-treatment-that-adapts-to-the-brain-16384?utm_campaign=DDN_Newsletter_Dose&utm_medium=email&_hsenc=p2ANqtz-9B9nWvgDzw34gRM8fwTPDFYg3So-fLxbbpLX6ULAGIg0J6tdoxERYuNXf11BaXtUdjkt0_w0WCdacBLORogALeSvd2aQ&_hsmi=403918635&utm_content=403918635&utm_source=hs_email

How Are Oral SERDs Changing the Management of Advanced HR-Positive Breast Cancer? Authors: Erica L. Mayer, MD, MPH; François-Clément Bidard, MD, PhD

https://www.medscape.org/viewarticle/how-are-oral-serds-changing-management-advanced-hr-positive-2025a1000xkg?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260216-OUS-HONC-how-are-oral-serds-changing-management-advanced-hr-positive-2025a1000xkg-cta

Achieving Brain Health in Epilepsy: What Can Clinicians Do? Authors: Marian Galovic, MD, PhD; Jane Allendorfer, PhD; Torie Robinson

https://www.medscape.org/viewarticle/achieving-brain-health-epilepsy-what-can-clinicians-do-2025a1000y6t?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_260215-12120309_ES_NEUR#transcript-download-es

Precision Oncology Meets RAS: Innovations in Targeting RAS-Addicted Solid Tumors Authors: Kathryn C. Arbour, MD; Aparna R. Parikh, MD, MS

https://www.medscape.org/viewarticle/precision-oncology-meets-ras-innovations-targeting-ras-2025a1000x8k?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260215-OUS-HONC-precision-oncology-meets-ras-innovations-targeting-ras-2025a1000x8k-cta

Rare Clinical Spotlight: Exploring Castleman Disease, Cold Agglutinin Disease, and Acute Intermittent Porphyria Authors: Ariela Noy, MD; Sudipto Mukherjee, MD, PhD, MPH; Angelika Erwin, MD, PhD; Bruce Wang, MD; Catherine Broome, MD; Ilene Weitz, MD

https://www.medscape.org/viewarticle/rare-clinical-spotlight-exploring-castleman-disease-cold-2025a100104i?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_il_mscpedu_260215-12133491-ES_LANG-HONC#transcript-download-es

Recurrent Near-Fainting Episodes in a 62-Year-Old Construction Supervisor With Asthma and Back Pain Heidi Moawad, MD January 26, 2026

https://reference.medscape.com/viewarticle/recurrent-near-fainting-episodes-62-year-old-construction-2026a10001kj?ecd=WNL_casechlg_260215_MSCPREF_etid8103531&uac=148436CN&impID=8103531

Advancing Personalized Care for Prostate Cancer: Patient-Centered Solutions for mHSPC and nmCRPC Authors: Alicia K. Morgans, MD, MPH, FASCO; Christian Gratzke, MD; Fred Saad, MD, FRCS, FCAHS; Tony Collier, BEM

https://www.medscape.org/viewarticle/advancing-personalized-care-prostate-cancer-patient-centered-2025a1000uyb?page=1&sso=true&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260215-OUS-HONC-advancing-personalized-care-prostate-cancer-patient-centered-2025a1000uyb-cta

‘Addiction machines’: Social media companies on trial, blamed for epidemic of suicides Lily Jamali | BBC | February 12, 2026

https://geneticliteracyproject.org/2026/02/12/addiction-machines-social-media-companies-on-trial-blamed-for-epidemic-of-suicides/

Unpasteurized milk scandal: 2% of the U.S. drinks unpasteurized milk but it causes 22x more infections Cambridge University Press | February 12, 2026

https://geneticliteracyproject.org/2026/02/12/unpasteurized-milk-scandal-2-of-the-u-s-drinks-unpasteurized-milk-but-it-causes-22x-more-infections/

No, supplements cannot prevent cancer or even help treat it, and they could even make things worse Mikkael Sekeres | Washington Post | February 13, 2026

https://geneticliteracyproject.org/2026/02/13/no-supplements-cannot-prevent-cancer-or-even-help-treat-it-and-they-could-even-make-things-worse/

Viewpoint—Vaccine rejectionists are trying to scare women that they are being used as ‘guinea pigs’ Aimee Pugh Bernard, David Higgins, Elana Pearl BenJoseph, Jess Steier | February 12, 2026

https://geneticliteracyproject.org/2026/02/12/viewpoint-vaccine-rejectionists-are-trying-to-scare-women-that-they-are-being-used-as-guinea-pigs/

GLP podcast: In defense of DDT—the pesticide that saved half a billion lives Cameron English, Liza Lockwood | February 13, 2026

https://geneticliteracyproject.org/2026/02/13/glp-podcast-in-defense-of-ddt-the-pesticide-that-saved-half-a-billion-lives/

Functional Food

Functional Food This hub provides a comprehensive overview and the latest news on functional foods, superfoods, and dietary components that contribute to health and disease prevention. The collection highlights bioactive compounds in foods such as lychee, chia seeds, dates, baobab fruit, and black sesame, alongside evidence-based discussions on fermented foods, postbiotics, and algae-based supplements. Readers will also find insights into the health benefits of traditional and modern diets, including the Atlantic and Washoku patterns, as well as functional beverages and plant-derived oils. By combining nutritional science, clinical research, and updates on emerging food innovations, this hub equips healthcare professionals, researchers, and health-conscious individuals with reliable knowledge to evaluate functional foods and their role in supporting long-term wellness. https://www.news-medical.net/condition/Functional-Food

Cardiologists highlight overlooked heart risks across women’s lives +++

Daily coffee intake linked to fewer atrial fibrillation relapses https://www.news-medical.net/news/20260130/Daily-coffee-intake-linked-to-fewer-atrial-fibrillation-relapses.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=cardiology_newsletter_8_february_2026 The study reveals that moderate coffee consumption may lower atrial fibrillation recurrence risk post-cardioversion, highlighting coffee's potential benefits. New model predicts redo surgery risk in adult congenital heart disease https://www.news-medical.net/news/20260131/New-model-predicts-redo-surgery-risk-in-adult-congenital-heart-disease.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=cardiology_newsletter_8_february_2026 Heart specialists at Mayo Clinic today presented new research at the 2026 Society of Thoracic Surgeons Annual Meeting that redo surgery for adults with congenital heart disease (CHD) remains high-risk, and a clinically applicable national risk assessment model is needed to help patients and care teams make decisions about procedures. Cardiologists highlight overlooked heart risks across women’s lives https://www.news-medical.net/news/20260203/Cardiologists-highlight-overlooked-heart-risks-across-womene28099s-lives.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=cardiology_newsletter_8_february_2026 Heart disease remains the leading cause of death for women in the United States, yet awareness of cardiovascular risk—particularly among younger women and women of color—has stalled, even as rates of high blood pressure, diabetes, obesity, and high cholesterol continue to rise.

Men develop premature heart disease earlier than women

https://www.news-medical.net/news/20260202/Men-develop-premature-heart-disease-earlier-than-women.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=cardiology_newsletter_8_february_2026 Researchers track heart disease from young adulthood to uncover when sex-based risk differences first emerge. In a recent study published in the Journal of the American Heart Association, a group of researchers examined sex-based differences in the age of onset of premature cardiovascular disease (CVD) and its major subtypes across adulthood.

Why cardiologist evaluation matters after non-cardiac surgery

https://www.news-medical.net/news/20260203/Why-cardiologist-evaluation-matters-after-non-cardiac-surgery.aspx?utm_source=news_medical_newsletter&utm_medium=email&utm_campaign=cardiology_newsletter_8_february_2026 Many post-surgical heart injuries go unnoticed, but cardiologist input can change outcomes. In a recent study published in the European Heart Journal, researchers analyzed data from more than 1,000 patients who developed perioperative myocardial injury to explain the potential mortality benefits of including a cardiologist in non-cardiac procedures, particularly for high-risk patients.

Engineered Listeria boosts innate immunity against cancer

https://www.news-medical.net/news/20260213/Engineered-Listeria-boosts-innate-immunity-against-cancer.aspx After nearly 40 years of research on how Listeria bacteria manipulate our cells and battle our immune system to cause listeriosis, Daniel Portnoy and his colleagues have discovered a way to turn the bacteria into a potent booster of the immune system - and a potential weapon against cancer.

US drinking water kiosks sometimes contain elevated lead levels

https://www.news-medical.net/news/20260213/US-drinking-water-kiosks-sometimes-contain-elevated-lead-levels.aspx After high-profile water crises like the one in Flint, Michigan, some Americans distrust the safety of tap water, choosing to purchase drinking water from freestanding water vending machines or kiosks. Yet this more expensive water may contain different pollutants than local tap water, according to a study in ACS' Environmental Science & Technology. Researchers report that water sampled from 20 kiosks in six states sometimes contained lead at levels above public health recommendations.

Vitamin A and thyroid hormones in the retina shape fetal vision

https://www.news-medical.net/news/20260213/Vitamin-A-and-thyroid-hormones-in-the-retina-shape-fetal-vision.aspx Humans develop sharp vision during early fetal development thanks to an interplay between a vitamin A derivative and thyroid hormones in the retina, Johns Hopkins University scientists have found.

Ozempic users continue treatment when weight loss works despite side effects

https://www.news-medical.net/news/20260213/Ozempic-users-continue-treatment-when-weight-loss-works-despite-side-effects.aspx An examination of user reviews finds that people continue off-label Ozempic when it delivers results, even if side effects persist. A recent study in the Journal of Medical Internet Research examined patients’ experiences with off-label Ozempic use for weight loss and identified factors that influence user satisfaction and treatment discontinuation.

Stopping vertical transmission requires global resolve The Lancet Microbe ++... ++

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