CIENCIASMEDICASNEWS: eBook: Overcoming Challenges in Cell Line Development

jueves, 27 de agosto de 2020

eBook: Overcoming Challenges in Cell Line Development

	Cell Biology
	The latest cell & molecular biology news from News Medical

Specialized cellular structures may hold clues to health effects of psychological stress

eBook: Overcoming Challenges in Cell Line Development

Advances in cell line engineering and microfluidic technologies provide significant opportunities to reduce timelines in cell line development (CLD). As with any change, optimizing the CLD processes can introduce new challenges and uncertainties. Some of the key challenges include: 1) selection bias in the cell line; 2) unpredictable gene expression; 3) issues with automated cloning techniques; 4) varying cell growth rates.

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Live-Cell Analysis of Cell Subsets and Heterogeneity

Considerable heterogeneity exists in individual cells, even in the simplest cell system. This article considers this opportunity from a perspective of analyzing living cells over time, describing new live-cell analysis solutions for quantifying the phenotypic biology of cell subsets in heterogeneous cultures.

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Exosomes: The cancer cell communication mechanism

Professor Deborah Goberdhan speaks to News-Medical about her team's latest research into cancer cells, and the mechanisms they use to communicate.

	New method reveals the dynamics of cell development and gene activity Studies on cellular dynamics are vital to interpret the development of cells and the progression of various diseases.

	New method helps track actin involved in mitochondrial dysfunction The human skeleton helps in moving the body. Similarly, fine skeleton-like filaments inside the cells also help in the movement of cellular structures.

	Researchers develop CAR-T cell therapy based on TCR signal transduction The T cell receptor (TCR) is a key receptor that is responsible for detecting tumor antigens in T cells.

	Study sheds new light on core regulatory networks that govern cell types in vertebrates The FANTOM Consortium has shed new light into the main regulatory networks that govern the types of cells found in different vertebrate species.

	Deep Learning On Cell Signaling Networks Establishes AI For Single-Cell Biology Computer systems that emulate key aspects of human problem solving are commonly referred to as AI. This field has seen massive progress over the last years.