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lunes, 17 de febrero de 2020

Medical News | Medical Articles | MSI by PCR ≠ MMR by IHC

	Bowel Cancer
	The latest bowel cancer news from News Medical

MSI by PCR ≠ MMR by IHC

Immunohistochemistry (IHC) detects the presence or absence of MMR proteins but won’t differentiate between functional and nonfunctional proteins. In contrast, MSI by PCR is a molecular test that determines if DNA mismatches are being repaired, making it a functional test for MMR protein activity.

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			Daily Aspirin use may help prevent colorectal cancer A new study has shown that regular use of aspirin may protect against heart disease, reduce colorectal tumor growth and prevent relapse.

			Researchers identify new pathway as biological target for colon cancer Researchers have found a way to help make chemotherapy more effective in treating colon cancer. They identified a new pathway (RICTOR/mTORC2) as a biological target for the disease.

	Research reveals key molecular target for colorectal cancer therapy Serine racemase is a multifunctional enzyme that carries out several different reactions in human cells, including the conversion of L-serine into pyruvate.

	Gut disease and gene analysis networks Gut diseases are difficult to diagnose in many cases, and their underlying dysfunction is hard to understand in many cases. Now, a new study published in the journal Molecular Omics promises to uncover a better insight into how these conditions occur and their mechanisms, by providing a deeper look at how genes interact in complex ways in health and fail to do so in disease.

	New machine learning platform can help spot colorectal cancers, predict disease severity A new machine learning platform can identify patients with colorectal cancer and helps predict their disease severity and survival, according to a study involving samples from thousands of subjects.

	Bariatric surgery may reduce risk of developing colorectal cancer by one-third Weight loss surgery may reduce the risk of developing colorectal cancer by one-third, according to an analysis of all relevant published studies.

	ACA improved access to life-saving care for young adult colorectal cancer patients An Affordable Care Act provision that allowed young adults to be covered under their parents' insurance led to a shift to earlier-stage diagnosis and more timely receipt of adjuvant chemotherapy among young colorectal cancer patients, according to a new American Cancer Society study. The study appears in JNCI.