Scleroderma
Also called: Circumscribed scleroderma, Dermatosclerosis, Morphea, Systemic sclerosisNational Institutes of Health
Scleroderma means hard skin. It is a group of diseases that cause abnormal growth of connective tissue. Connective tissue is the material inside your body that gives your tissues their shape and helps keep them strong. In scleroderma, the tissue gets hard or thick. It can cause swelling or pain in your muscles and joints.
Symptoms of scleroderma include
- Calcium deposits in connective tissues
- Raynaud's phenomenon, a narrowing of blood vessels in the hands or feet
- Swelling of the esophagus, the tube between your throat and stomach
- Thick, tight skin on your fingers
- Red spots on your hands and face
No one knows what causes scleroderma. It is more common in women. It can be mild or severe. Doctors diagnose scleroderma using your medical history, a physical exam, lab tests, and a skin biopsy. There is no cure, but various treatments can control symptoms and complications.
NIH: National Institute of Arthritis and Musculoskeletal and Skin Diseases
- ANA (Antinuclear Antibody) Test (National Library of Medicine)Also in Spanish
- Available Treatments for Complications and Conditions Associated with Scleroderma (Scleroderma Research Foundation)
- Coping with Scleroderma (Scleroderma Foundation) - PDF
- Eating Well with Scleroderma (Scleroderma Foundation) - PDF
- Dental Care in Scleroderma (Scleroderma Foundation) - PDF
- Pulmonary Hypertension in Scleroderma (Scleroderma Foundation) - PDF
- Scleroderma and Sexuality (Scleroderma Foundation) - PDF
- Limited Scleroderma (CREST Syndrome) (Mayo Foundation for Medical Education and Research)Also in Spanish
- Localized Scleroderma (Scleroderma Foundation) - PDFAlso in Spanish
- Morphea (American Osteopathic College of Dermatology)
- Systemic Sclerosis: Diffuse and Limited (Scleroderma Foundation) - PDF
- Genetics Home Reference: systemic scleroderma (National Library of Medicine)
- Arthritis by the Numbers: Book of Trusted Facts & Figures (Arthritis Foundation) - PDF
- International Team Identifies Biomarker for Scleroderma (National Institute of Arthritis and Musculoskeletal and Skin Diseases)
- Novel Insights Into Causes of Scleroderma Offer Potential New Treatment Strategies (National Institute of Arthritis and Musculoskeletal and Skin Diseases)
- ClinicalTrials.gov: Scleroderma, Localized (National Institutes of Health)
- ClinicalTrials.gov: Scleroderma, Systemic (National Institutes of Health)
- Find a Rheumatologist (American College of Rheumatology)
- National Institute of Arthritis and Musculoskeletal and Skin Diseases Also in Spanish
- Juvenile Scleroderma (Scleroderma Foundation) - PDF
- Collagen vascular disease (Medical Encyclopedia)Also in Spanish
- Scleroderma (Medical Encyclopedia)Also in Spanish
- Swallowing problems (Medical Encyclopedia)Also in Spanish
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