Precision Medicine and Population Health: Dealing With the Elephant in the Room
In this week’s Journal of American Medical Association, we published a point-counterpoint commentary on the impact of precision medicine on population health. Announcement of the news of the US precision medicine initiative has been met with a range of responses from enthusiasm to skepticism about potential benefits, limitations and return on investment. In considering the Read More >
Posted on by Muin J. Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia, and Sandro Galea, Dean, School of Public Health, Boston University, Boston, Massachusetts1 CommentCategories precision medicine
Tags population healthThe Shift From Personalized Medicine to Precision Medicine and Precision Public Health: Words Matter!
Advances in genomics and other ‘omic’ technologies have ushered in a new era variably called “personalized” or “precision” medicine, which takes into account individual genetic and other sources of variability in disease treatment and prevention. In the past decade, we have seen a significant growth in interest and usage of the terms personalized and precision Read More >
Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and Prevention1 CommentCancer Precision Medicine: More Population Sciences Ahead!
We explore briefly the expanding role of population sciences in the implementation of the NIH Precision Medicine Initiative (PMI). The initiative includes a major component on cancer precision treatment, and a large scale cohort study program to generate knowledge applicable to all areas of health and disease, including cancer risk factors and outcomes. Genomics is Read More >
Posted on by Muin J. Khoury MD, PhD, Director, Office of Public Health Genomics, Centers for Disease Control and Prevention, Atlanta, Georgia and Debbie Winn PhD, Deputy Director, Division of Cancer Control and Population Sciences, National Cancer Institute, Rockville, MarylandLeave a commentTags genomicsPrecision Medicine: the Arrival of Genomics to the Clinic is the Beginning of a Longer Journey
It has been a year since the announcement of the new US Precision Medicine Initiative. As new funding is awarded to investigators across the country, the pace of assembling the cohort of a million or more individuals will accelerate. This cohort will link information from genomic, behavioral, social, environmental, and health outcomes to discover and Read More >
Posted on by Muin J. Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and Prevention, and Gregory Feero, MD, PhD, Maine Dartmouth Family Medicine ResidencyLeave a commentTags clinics, genomicsPublic Health Genomics 2015: Looking Back, Looking Ahead
In 2015, the United States launched the precision medicine initiative that includes a cancer component and a national cohort research study of one million or more people. While much of this initiative will take years to develop outputs for use in health care, a public health perspective is crucial to ensure the initiative’s success in Read More >
Posted on by Muin J Khoury, Director, Office of Public Health Genomics, Centers for Disease Control and PreventionLeave a commentTags pathogenEngaging Implementation Scientists in Precision Medicine
From the State of the Union through a number of NIH-led workshops to a report from the Advisory Committee to the NIH Director [PDF 1.05 MB], and the recently launched NIH funding announcements, the Precision Medicine Initiative has the potential to reimagine how we can use information on our biology, our environment, our experiences, our Read More >
Posted on by David A. Chambers, D.Phil., Deputy Director for Implementation Science, Division of Cancer Control and Population Sciences, National Cancer InstituteLeave a commentTags implementation, scientistGenomic discoveries to clinical applications: Are we reaching an inflection point toward precision medicine?
Each year at the annual American Society of Human Genetics (ASHG) meeting I follow certain rituals. During the first “poster session”, I quickly peruse all of the vendor booths on the floor to assess something of the overall flavor of the commercial space’s focus. During the next two poster sessions I cruise all of the Read More >
Posted on by W. Gregory Feero, MD, PhD, Maine Dartmouth Family Medicine ResidencyLeave a commentCategories precision medicine
Tags genomics, precision medicine, public healthPrecision Medicine vs. Public Health: a False Dichotomy?
The recent focus on precision medicine has attracted criticism from the public health community that firmly believes that health is determined by far more than health care, and that more sophisticated medical technologies may not adequately address important determinants of population health. There is no argument that a focus on the wider environmental, structural and Read More >
Posted on by Ron Zimmern, PHG Foundation and Muin J. Khoury, Office of Public Health Genomics, Centers for Disease Control and PreventionLeave a commentInfectious Diseases: Precision Medicine for Public Health
Until now, most medical treatments have been designed for the “average patient.” As a result of this “one-size-fits-all” approach, treatments can be very successful for some patients but not for others. Precision Medicine, on the other hand, is an innovative approach that takes into account individual differences in people’s genes, environments, and lifestyles. The Precision Read More >
Posted on by Marta Gwinn, Consultant, McKing Consulting Corp, Office of Public Health Genomics and Duncan MacCannell (NCEZID), Centers for Disease Control and PreventionLeave a commentTags infectious diseaseThe Future of Epidemiology in the Age of Precision Medicine: Cancer, Cardiovascular Disease, and Beyond
We live in the era of “Big Data.” Evaluating the health impact of large scale biological, social, and environmental data is an emerging challenge. Epidemiology, the study of the distribution and determinants of human disease in populations, is a foundational science of public health and provides important insights for medical practice and disease prevention. Epidemiology has Read More >
Posted on by Muin J. Khoury M.D., Ph.D., Office of Public Health Genomics, Centers for Disease Control and Prevention, and Gina S. Wei, M.D., M.P.H., Division of Cardiovascular Sciences, National Heart, Lung, and Blood Institute1 Comment
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