CIENCIASMEDICASNEWS: Medical News | Medical Articles: Alignment of the Movable Objective Microscope

jueves, 24 de octubre de 2019

Medical News | Medical Articles: Alignment of the Movable Objective Microscope

	October 23, 2019
	Life Science Microscopy
	The latest life science microscopy news from News Medical

Alignment of the Movable Objective Microscope

Two-photon imaging systems rely on accurate beam alignment for optimal performance. In this tutorial, we will walk through the steps of aligning a Sutter two-photon microscope using a special laser alignment tool and custom pinholes for the Sutter Movable Objective Microscope (MOM^®).

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			Confocal Versus Super-resolution Microscopy Super-resolution microscopy refers to a collection of methods used to increase the resolution of light microscopy, whereas confocal microscopy uses a laser beam to increase the signal intensity from the sample.

			New chip-sized microscope focuses on super-resolution viewing An EU-funded project is developing a super-resolution microscope small enough to fit on to a computer chip that can be used to see changes in living cells in real time.

Why are you seeing this?

	Super-Resolution Microscopy vs. Electron Microscopy Conventional light microscopy has its limits. Light, being a wave, is subject to diffraction which severely limits the size of structures one can resolve. To be able to observe parts of an organism smaller than this, other techniques need to be employed.

	Confocal Reflection Microscopy for Cell Migration Studies Cell migration occurs throughout life as a response to internal and external signals, and can as such be indicative of changes occurring in the body. Imaging this movement and what processes control it can be critical in understanding cell behavior, development, and disease.

	An Introduction to IR Nanochemical Mapping AFM-IR compositional mapping of Streptomyces bacteria. Left: AFM topographic image of bacterial cells. Middle: AFM-IR absorption at 1650 cm−1, corresponding to the amide I band associated with protein. Right: AFM-IR absorption at the carbonyl band 1740 cm−1, indicating the distribution of triglyceride vesicles within bacterial cells.