Calcium pyrophosphate arthritis
Calcium pyrophosphate dihydrate (CPPD) arthritis is a joint disease that can cause attacks of arthritis. Like gout, crystals form in the joints. But in this arthritis, the crystals are not formed from uric acid.
Deposition of calcium pyrophosphate dihydrate (CPPD) causes this form of arthritis. The buildup of this chemical forms crystals in the joints. This leads to attacks of joint swelling and pain in the knees, wrists, ankles, and other joints.
Among older adults, CPPD is a common cause of sudden (acute) arthritis in one joint. The attack is caused due to:
- Injury to the joint
- Hyaluronate injection in the joint
- Medical illness
CPPD arthritis mainly affects the elderly because joint degeneration and osteoarthritis increases with age. Such joint damage increases the tendency of CPPD deposition. However, CPPD arthritis can sometimes affect younger people who have conditions such as:
- Hemochromatosis
- Parathyroid disease
- Dialysis-dependent renal failure
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