Preliminary evidence for physical activity following pelvic exenteration: a pilot longitudinal cohort study

Daniel SteffensEmail author View ORCID ID profile,
Jane M. Young,
Michael Solomon,
Paula R. Beckenkamp,
Cherry Koh,
Kenneth Vuong,
Matthew A. Brodie and
Kim Delbaere

BMC Cancer201919:661

https://doi.org/10.1186/s12885-019-5860-5

Received: 24 November 2018
Accepted: 20 June 2019
Published: 4 July 2019

Open Peer Review reports

Abstract

Background

The physical activity (PA) level of patients undergoing major cancer surgery remains unclear. This pilot study aimed to: (i) Compare preoperative PA level between patients undergoing major cancer surgery and the general population; (ii) describe PA trajectories following major cancer surgery; (iii) Compare objective versus subjective PA measures in patients undergoing major cancer surgery; and (iv) Investigate the association between preoperative PA level and postoperative outcomes.

Methods

Patients undergoing pelvic exenteration between September/2016 and September/2017 were included and followed at preoperative, 6-weeks and 6-months postoperative. PA was measured using the International Physical Activity Questionnaire Short-Form and McRoberts activity monitor. Analyses were performed using SPSS.

Results

This pilot study included 16 patients. When compared to the general population, patients undergoing major cancer surgery presented a reduced preoperative PA level. PA levels decreased at 6 weeks but returned to preoperative levels at 6 months postoperative. Objective and subjective measures of PA were comparable, with some variables presenting strong correlations. A higher preoperative level PA was associated with an absence of postoperative complications and better quality of life outcomes.

Conclusions

Patients undergoing major cancer surgery demonstrated lower PA levels when compared to the general population. PA trajectories decreased at 6 weeks postoperative, returning to preoperative levels within 6-months. In this cohort, it seems that higher preoperative PA level may improve postoperative surgical outcomes; however, this preliminary evidence should be confirmed in a larger cohort.