Avoiding methodological bias in studies of amyloid imaging results disclosure | Alzheimer's Research & Therapy | Full Text

Avoiding methodological bias in studies of amyloid imaging results disclosure | Alzheimer's Research & Therapy | Full Text



Alzheimer's Research & Therapy

Avoiding methodological bias in studies of amyloid imaging results disclosure

• Carl TaswellEmail authorView ORCID ID profile,
• Cheryl Donohue,
• Maree T. Mastwyk,
• Andrea G. Louey,
• Jacqueline Giummarra,
• Joanne Robertson,
• David G. Darby,
• Colin L. Masters and
• Christopher C. Rowe

Alzheimer's Research & Therapy201911:52

https://doi.org/10.1186/s13195-019-0495-y

©  The Author(s). 2019

• Published: 4 June 2019

We read with interest the paper by Grill et al. [1], a study of N = 33 participants interviewed about their reactions to learning that their amyloid imaging results were “not elevated” in a preclinical Alzheimer’s disease (AD) trial. We welcome their contribution to the literature and would like to call attention to some related larger-size studies by Wake et al. [2] (with N = 42 subjects) and by Taswell et al. [3] (with N = 133 subjects) that were not cited in the paper by Grill et al. [1].