Strategies to Prevent S. aureus BSIs in Acute Care Facilities | CDC

Strategies to Prevent S. aureus BSIs in Acute Care Facilities | CDC

2. IMPLEMENT SOURCE CONTROL STRATEGIES FOR HIGH RISK PATIENTS DURING HIGH RISK PERIODS

• Core Strategy:
  • Pursue a strategy to reduce carriage of S. aureus among all patients admitted to intensive care units (ICUs) (see table for summary of source control strategies) including:
    • Apply intranasal mupirocin twice a day to each nare for 5 days in conjunction with  daily chlorhexidine bathing for duration of ICU admission
      • Intranasal iodophor could be considered as an alternative to intranasal mupirocin
      • For more information see: Universal ICU Decolonization: An Enhanced Protocol. Agency for Healthcare Research and Quality (AHRQ).
• Supplemental Strategy
  • Pursue a strategy to reduce carriage of S. aureus for patients hospitalized with CVCs or midline catheters outside the ICU
    • Apply intranasal mupirocin twice a day to each nare for 5 days in conjunction with daily chlorhexidine bathing while CVC or midline catheter is present
      • Intranasal iodophor could be considered as an alternative to intranasal mupriocin