Sleep Disorders and Genomics: What's New?

Specific PHGKB|HLBS|PHGKB

What's New

Last Posted: Feb 28, 2019

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• A distinctive DNA methylation pattern in insufficient sleep.  
  Lahtinen Alexandra et al. Scientific reports 2019 Feb 9(1) 1193
• Insomnia tied to depression, cardiovascular disease  
  M Prize, Science, February 25, 2019
• Associations Between Pre-Sleep Arousal and Insomnia Symptoms in Early Adulthood: A Twin and Sibling Study.  
  Schneider Melanie N et al. Sleep 2019 Feb
• Genome-wide analysis of insomnia in 1,331,010 individuals identifies new risk loci and functional pathways  
  PR Jansen et al, Nature Genetics, February 25, 2019
• Digitizing the way to better sleep health  
  SJ Jaiswal et al, Lancet, February 14, 2019
• Polygenic risk score identifies associations between sleep duration and diseases determined from an electronic medical record biobank.  
  Dashti Hassan S et al. Sleep 2018 Dec
• Clinical and Experimental Human Sleep-Wake Pharmacogenetics.  
  Landolt Hans-Peter et al. Handbook of experimental pharmacology 2018 Nov
• Investigating causal relationships between sleep traits and risk of breast cancer: a Mendelian randomization study  
  RC Richmond et al, BIORXIOV, November 2018
• Pharmacogenomics and Biomarkers of Depression.  
  Jha Manish K et al. Handbook of experimental pharmacology 2018 Oct
• Correlation between HLA-DQB1*06:02 and narcolepsy with and without cataplexy: approving a safe and sensitive genetic test in four major ethnic groups. A systematic meta-analysis.  
  Capittini C et al. Sleep medicine 2018 Sep 52150-157
• New supplemental awards boost NIH funding for research on Down syndrome  
  NIH, October 1, 2018
• Precision medicine in circadian rhythm sleep-wake disorders: current state and future perspectives.  
  Keijzer Henry et al. Personalized medicine 2017 14(2) 171-182
• NIH launches initiative to accelerate genetic therapies to cure sickle cell disease  
  NIH, September 13, 2018
• HLBS-PopOmics: an online knowledge base to accelerate dissemination and implementation of research advances in population genomics to reduce the burden of heart, lung, blood, and sleep disorders.  
  Mensah George A et al. Genetics in medicine : official journal of the American College of Medical Genetics 2018 Sep
• Just 21 People Are Known to Have This Rare Genetic Condition. Can You Help Us Find More?  
  L Sanders, New York Times, August, 2018
• A Molecular Reason Why Obese People Have Trouble Losing Weight  
  B Stetka, Scientific American, August 23, 2018
• One woman’s race to defuse the genetic time bomb in her genes  
  A Regalado, Tech Review, July 23, 2018
• Stimulating Implementation Science in Genomics and Precision Medicine for Heart, Lung, Blood and Sleep Diseases: The Case of Familial Hypercholesterolemia
  MJ Khoury et al, Blog Post, June 5, 2018
• The Use of Precision Medicine to Manage Obstructive Sleep Apnea Treatment in Patients with Resistant Hypertension: Current Evidence and Future Directions.  
  Sapiña Esther et al. Current hypertension reports 2018 Jun 20(7) 60
• NIH statement on World Asthma Day 2018  
  NIH video: patients and scientists work together to advance asthma research.