Symptom Management for Patients with Advanced Illness -- Cycle 2 2018 | PCORI

Symptom Management for Patients with Advanced Illness -- Cycle 2 2018 | PCORI

Symptom Management for Patients with Advanced Illness -- Cycle 2 2018

The Patient-Centered Outcomes Research Institute (PCORI) seeks to fund multiple high-quality clinical studies that compare the effectiveness of evidence-based treatments for relief of common symptoms experienced by patients with serious, advanced illness. For the Cycle 2 2018 PFA, PCORI has refined the requirements for choosing comparative treatments, and removed depression from the symptom list. The goal of this funding initiative is to support patient- and caregiver-centered, comparative clinical effectiveness research that aims to generate important findings to aid decision making for symptom management in advanced illness.

Symptoms of specific interest for this funding opportunity include pain, fatigue, dyspnea, insomnia, anorexia/cachexia, nausea/vomiting, and anxiety. Study populations should include patients with serious, life-limiting diagnoses, including but not limited to advanced heart failure, cancer, chronic obstructive pulmonary disease, or neurodegenerative disease. This announcement includes a specific mention of complementary therapies, including music therapy. PCORI is particularly interested in studies that seek to increase the evidence base for effective treatments in pediatric and adolescent populations, in whom fewer studies have been completed. Research questions should incorporate long-term outcomes; plans should incorporate a minimum of six months of participant follow-up.

Letters of Intent Due:  Thursday, June 28, 2018, by 5:00 p.m. ET.NOTE: Those selected to submit a full application will be notified by Monday, July 23, 2018.
Full applications Due: Tuesday, September 25, 2018, by 5:00 p.m. ET.

Read the funding announcement