New on the MedlinePlus Bone Marrow Diseases page:
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Bone marrow is the spongy tissue inside some of your bones, such as your hip and thigh bones. It contains stem cells. The stem cells can develop into the red blood cells that carry oxygen through your body, the white blood cells that fight infections, and the platelets that help with blood clotting.
With bone marrow disease, there are problems with the stem cells or how they develop:
- In leukemia, a cancer of the blood, the bone marrow makes abnormal white blood cells
- In aplastic anemia, the bone marrow doesn't make red blood cells
- In myeloproliferative disorders, the bone marrow makes too many white blood cells
- Other diseases, such as lymphoma, can spread into the bone marrow and affect the production of blood cells
Causes of bone marrow diseases include genetics and environmental factors. Tests for bone marrow diseases include blood and bone marrow tests. Treatments depend on the disorder and how severe it is. They might involve medicines, blood transfusions or a bone marrow transplant.
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- Genetics Home Reference: 8p11 myeloproliferative syndrome (National Library of Medicine)
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- Genetics Home Reference: polycythemia vera (National Library of Medicine)
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- Genetics Home Reference: Shwachman-Diamond syndrome (National Library of Medicine)
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- ClinicalTrials.gov: Bone Marrow Diseases (National Institutes of Health)
- ClinicalTrials.gov: Myeloproliferative Disorders (National Institutes of Health)
- Inherited Bone Marrow Failure Syndromes Glossary of Terms (National Cancer Institute)
- Bone marrow aspiration (Medical Encyclopedia)Also in Spanish
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- Bone marrow transplant (Medical Encyclopedia)Also in Spanish
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- Myelofibrosis (Medical Encyclopedia)Also in Spanish
- Polycythemia vera (Medical Encyclopedia)Also in Spanish
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