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National Guideline Clearinghouse | Acromegaly: an Endocrine Society clinical practice guideline.

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National Guideline Clearinghouse | Acromegaly: an Endocrine Society clinical practice guideline.

The Endocrine Society

Guideline Title

Acromegaly: an Endocrine Society clinical practice guideline.

Bibliographic Source(s)

Katznelson L, Laws ER Jr, Melmed S, Molitch ME, Murad MH, Utz A, Wass JAH, Endocrine Society. Acromegaly: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2014 Nov;99(11):3933-51. [219 references] PubMed External Web Site Policy

Guideline Status

This is the current release of the guideline.

This guideline meets NGC's 2013 (revised) inclusion criteria.

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Acromegaly: an endocrine society clinical practice guideline. - PubMed - NCBI

2014 Nov;99(11):3933-51. doi: 10.1210/jc.2014-2700. Epub 2014 Oct 30.

Acromegaly: an endocrine society clinical practice guideline.

Katznelson L1, Laws ER Jr, Melmed S, Molitch ME, Murad MH, Utz A, Wass JA; Endocrine Society.

Author information

Abstract

OBJECTIVE:

The aim was to formulate clinical practice guidelines for acromegaly.

PARTICIPANTS:

The Task Force included a chair selected by the Endocrine Society Clinical Guidelines Subcommittee (CGS), five experts in the field, and a methodologist. The authors received no corporate funding or remuneration. This guideline is cosponsored by the European Society of Endocrinology.

EVIDENCE:

This evidence-based guideline was developed using the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system to describe both the strength of recommendations and the quality of evidence. The Task Force reviewed primary evidence and commissioned two additional systematic reviews.

CONSENSUS PROCESS:

One group meeting, several conference calls, and e-mail communications enabled consensus. Committees and members of the Endocrine Society and the European Society of Endocrinology reviewed drafts of the guidelines.

CONCLUSIONS:

Using an evidence-based approach, this acromegaly guideline addresses important clinical issues regarding the evaluation and management of acromegaly, including the appropriate biochemical assessment, a therapeutic algorithm, including use of medical monotherapy or combination therapy, and management during pregnancy.