Media Availability: HVTN 505 Vaccine Induced Antibodies Nonspecific for HIV

Media Availability: HVTN 505 Vaccine Induced Antibodies Nonspecific for HIV

Thursday July 30, 2015

Exploring the Role of the Microbiome 

in Vaccine-induced Immunity

Researchers from NIAID and Duke Medicine uncover why a candidate HIV vaccine did not work well. The candidate vaccine stimulated antibodies that recognized HIV as well as microbes commonly found in the intestinal tract, part of the body’s microbiome, but these antibodies were not protective against HIV. 

Understanding how the microbiome influences the effectiveness of vaccine-induced immunity will inform ongoing vaccine research efforts against HIV and other infectious diseases.