Muscular Dystrophies: Recent Public Health and Genomic Insights - July 1, 2015

Genomics|Features|Duchenne Muscular Dystrophy

Duchenne Muscular Dystrophy

Muscular Dystrophies: Recent Public Health and Genomic Insights - July 1, 2015

CDC and Related Info

• Population-based prevalence of Duchenne and Becker Muscular Dystrophies in the United States
• CDC Muscular Dystrophy Research
• CDC scientific articles on Muscular Dystrophy
• Muscular dystrophies are a group of genetic disorders that result in muscle weakness over time
• Muscular dystrophy- Kevin's Story

Duchenne muscular dystrophy: High-resolution melting curve analysis as an affordable diagnostic mutation scanning tool in a South African cohort.
Esterhuizen AI et al. S. Afr. Med. J. 2014 Nov 104(11) 779-84

Genetic and clinical profile of patients of Duchenne Muscular Dystrophy: Experience from a tertiary care center in Eastern India.
Dey S et al. Indian Pediatr 2015 Jun 8. 52(6) 481-4

CDC Key Findings: Population-based prevalence of Duchenne and Becker Muscular Dystrophies in the United States
First population-based prevalence on Duchenne and Becker Muscular Dystrophy in the United States by race and ethnicity

CDC paper: Prevalence of Duchenne and Becker Muscular Dystrophies in the United States
Paul A. Romitti, et al. Pediatrics, February 2015

CDC Muscular Dystrophy Research
CDC's Muscular Dystrophy Surveillance Tracking and Research Network is the only population-based muscular dystrophy tracking program in the United States

Sibling concordance for clinical features of Duchenne and Becker muscular dystrophies.
Pettygrove Sydney et al. Muscle Nerve 2014 Jun (6) 814-21

CDC scientific articles on Muscular Dystrophy

Online self-report data for duchenne muscular dystrophy confirms natural history and can be used to assess for therapeutic benefits.
Wang Richard T et al. PLoS Curr 2014

The TREAT-NMD DMD Global database: Analysis of more than 7000 Duchenne Muscular Dystrophy mutations.
Bladen Catherine L et al. Hum. Mutat. 2015 Jan 21.

Human artificial chromosomes for Duchenne muscular dystrophy and beyond: challenges and hopes.
Tedesco Francesco Saverio et al. Chromosome Res. 2015 Jan 18.

Duchenne muscular dystrophy gene therapy in the canine model.
Duan Dongsheng et al. Hum Gene Ther Clin Dev 2015 Jan 14.

Prevalence of muscular dystrophies: a systematic literature review.
Theadom Alice et al. Neuroepidemiology 2014 (3-4) 259-68

Muscular Dystrophy: Recent Genomic Insights - September 4, 2014

CDC information: Muscular dystrophies are a group of genetic disorders that result in muscle weakness over time

New CDC findings from the Muscular Dystrophy Surveillance Tracking and Research Network, the only population-based muscular dystrophy tracking program in the United States

CDC information: Muscular dystrophy- Kevin's Story

Our beautiful sons could die before us, by Nick Taussig, The Guardian, Aug 15 

Check out genetic disorders and tests associated with muscular dystrophy from the NIH Genetic Testing Registry

Recent insights

Prevention of muscular dystrophy in mice by CRISPR/Cas9–mediated editing of germline DNA. 
Chengzu Long et al. Science, August 14, 2014

Therapeutic prospects for CRISPR genome editing, by Phillipa Price, PHG Foundation, Aug 21

Genomics|Features|Duchenne Muscular Dystrophy