Addiction: Genomics and Public Health - June 29, 2015

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Addiction

Addiction: Genomics and Public Health - June 29, 2015

CDC and Related Info

• About drugs and addiction
• Genes reported in relation to addiction, including genomewide association studies via theHuGE Navigator

Addiction- Nature Outlook Issue
Brian Owens, Nature Outlook, June 24, 2015

Genetics: No more addictive personality
M Szalavitz, Nature Outlook, June 24, 2015

Addiction: 4 big questions
D Holmes, Nature Outlook, June 24, 2015

Alcohol dependence genetics: lessons Learned from genome-wide association studies (GWAS) and post-GWAS analyses.
Hart AB et al. Alcohol. Clin. Exp. Res. 2015 Jun 25.

Intrinsic plasticity: an emerging player in addiction.
Kourrich S et al. Nat. Rev. Neurosci. 2015 Mar (3) 173-84

Common single nucleotide variants underlying drug addiction: more than a decade of research.
Bühler KM et al. Addict Biol 2015 Jan 21.

CDC information: About drugs and addiction

NIH information: The science of drug abuse and addiction

A family health history of alcoholism: Are you at risk? From the National Institute of Alcohol Abuse and Alcoholism

CDC statistics show opiate addiction a growing threat across country, The Herald News, May 2014

Find out how opioid prescription drugs are affected by genetic differences in metabolism and which drugs have labels or dosing guidelines PharmGKB: A comprehensive resource that curates knowledge about the impact of genetic variation on drug response for clinicians and researchers

Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for cytochrome P450 2D6 (CYP2D6) genotype and codeine therapy: 2014 Update- 2014 supplement  [PDF 293.44 KB]

Podcast: New codeine guideline and more help with pharmacogenomics

Addiction medicine: The birth of a new discipline
Patrick G. O'Connor et al. JAMA Internal Medicine, September 8, 2014  

Addiction: How our genes program our preferences and habits, by Ben Locwin, Genetic Literacy Project,  Sept 11

Did you know? 388 genes have been reported in relation to addiction susceptibility and outcomes, including 41 genomewide associations. To find out more, visit the HuGE Navigator

Jump in deaths from narcotic painkillers, by Steven Reinberg, WebMD, Sep 16

Pharmacogenetic approaches in the treatment of alcohol use disorders: addressing clinical utility and implementation thresholds.
Hendershot CS.Addict Sci Clin Pract. 2014 Sep 13;9(1):20.