National Guideline Clearinghouse | MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy.

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National Guideline Clearinghouse | MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy.



Multinational Association of Supportive Care in Cancer

Guideline Title

MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy.

Bibliographic Source(s)

Lalla RV, Bowen J, Barasch A, Elting L, Epstein J, Keefe DM, McGuire DB, Migliorati C, Nicolatou-Galitis O, Peterson DE, Raber-Durlacher JE, Sonis ST, Elad S, Mucositis Guidelines Leadership Group of the MASCC/ISOO [trunc]. MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer. 2014 May 15;120(10):1453-61. [40 references]PubMed

Guideline Status

This is the current release of the guideline.

This guideline updates a previous version: Keefe DM, Schubert MM, Elting LS, Sonis ST, Epstein JB, Raber-Durlacher JE, Migliorati CA, McGuire DB, Hutchins RD, Peterson DE, Mucositis Study Section of the Multinational Association of Supportive Care in Cancer, International Society for Oral Oncology. Updated clinical practice guidelines for the prevention and treatment of mucositis. Cancer. 2007 Mar 1;109(5):820-31. [58 references]

This guideline meets NGC's 2013 (revised) inclusion criteria.

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MASCC/ISOO clinical practice guidelines for the management of mucos... - PubMed - NCBI

Cancer. 2014 May 15;120(10):1453-61. doi: 10.1002/cncr.28592. Epub 2014 Feb 25.

MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy.

Lalla RV1, Bowen J, Barasch A, Elting L, Epstein J, Keefe DM, McGuire DB, Migliorati C, Nicolatou-Galitis O, Peterson DE, Raber-Durlacher JE, Sonis ST, Elad S; Mucositis Guidelines Leadership Group of the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO).

Collaborators (12)

Author information

Abstract

BACKGROUND:

Mucositis is a highly significant, and sometimes dose-limiting, toxicity of cancer therapy. The goal of this systematic review was to update the Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO) Clinical Practice Guidelines for mucositis.

METHODS:

A literature search was conducted to identify eligible published articles, based on predefined inclusion/exclusion criteria. Each article was independently reviewed by 2 reviewers. Studies were rated according to the presence of major and minor flaws as per previously published criteria. The body of evidence for each intervention, in each treatment setting, was assigned a level of evidence, based on previously published criteria. Guidelines were developed based on the level of evidence, with 3 possible guideline determinations: recommendation, suggestion, or no guideline possible.

RESULTS:

The literature search identified 8279 papers, 1032 of which were retrieved for detailed evaluation based on titles and abstracts. Of these, 570 qualified for final inclusion in the systematic reviews. Sixteen new guidelines were developed for or against the use of various interventions in specific treatment settings. In total, the MASCC/ISOO Mucositis Guidelines now include 32 guidelines: 22 for oral mucositis and 10 for gastrointestinal mucositis. This article describes these updated guidelines.

CONCLUSIONS:

The updated MASCC/ISOO Clinical Practice Guidelines for mucositis will help clinicians provide evidence-based management of mucositis secondary to cancer therapy.

© 2014 The Authors. Cancer published by Wiley Periodicals, Inc. on behalf of American Cancer Society.

KEYWORDS:

Multinational Association of Supportive Care in Cancer and International Society of Oral Oncology (MASCC/ISOO); gastrointestinal; guidelines; mucositis; oral; stomatitis

PMID:

 

24615748

 

[PubMed - indexed for MEDLINE] 

PMCID:

 

PMC4164022

 

Free PMC Article