Genomics|Update|Current
Healthy Aging and Longevity: Role of Genomics
In a new approach to fighting disease, helpful genetic mutations are sought, by Gina Kolata, New York Times, Dec 28, 2014
The Resilience Project: A search for unexpected heroes,Icahn Mount Sinai, School of Medicine
The good mutations, GenomeWeb, Dec 30, 2014 [by free subscription only]
Researchers examine supercentenarians' genomes for longevity key, by Brooke Wolford, National Human Genome Research Institute, December 2014
Whole-genome sequencing of the world's oldest people.
Gierman HJ, et al. PLoS One. 2014 Nov 12;9(11):e112430
Gierman HJ, et al. PLoS One. 2014 Nov 12;9(11):e112430
Disease variants in genomes of 44 centenarians.
Freudenberg-Hua Y, et al. Mol Genet Genomic Med. 2014 Sep;2(5):438-50
Freudenberg-Hua Y, et al. Mol Genet Genomic Med. 2014 Sep;2(5):438-50
Why genes extending lifespan in model organisms have not been consistently associated with human longevity and what it means to translation research.
de Magalhães JP. Cell Cycle. 2014 Sep 1;13(17):2671-3.
de Magalhães JP. Cell Cycle. 2014 Sep 1;13(17):2671-3.
GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.
Broer L, et al. J Gerontol A Biol Sci Med Sci. 2015 Jan;70(1):110-8.
Broer L, et al. J Gerontol A Biol Sci Med Sci. 2015 Jan;70(1):110-8.
Genetic analysis of long-lived families reveals novel variants influencing high density-lipoprotein cholesterol.
Feitosa MF, et al. Front Genet. 2014 Jun 3;5:159
Feitosa MF, et al. Front Genet. 2014 Jun 3;5:159
Check out our Aging update page for additional information and links
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