domingo, 28 de julio de 2013

Genomic Medicine, Precision Medicine, Pe... [Clin Pharmacol Ther. 2013] - PubMed - NCBI

Genomic Medicine, Precision Medicine, Pe... [Clin Pharmacol Ther. 2013] - PubMed - NCBI

Genomic Medicine, Precision Medicine, Personalized Medicine: What's in a Name?


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Genomic medicine, precision medicine, personalized medicine: What's in a name?External Web Site Icon
Roden DM & Tyndale RF Clin Pharmacol Ther 2013 Aug;94(2):169-72
The opportunities and challenges of implementing genomics-informed personalized medicineExternal Web Site Icon
Chisholm RL Clin Pharmacol Ther 2013 Aug;94(2):181-2
CYP2D6 genotype should not be used to determine endocrine therapy in postmenopausal breast cancer patientsExternal Web Site Icon
Rae JM Clin Pharmacol Ther 2013 Aug;94(2):183-5
CYP2D6 genotype and tamoxifen cctivity: Understanding interstudy variability in methodological qualityExternal Web Site Icon
Ratain MJ, et al. Clin Pharmacol Ther 2013 Aug;94(2):185-7
Genomic medicine: too great expectations?External Web Site Icon
O'Rourke PP Clin Pharmacol Ther 2013 Aug;94(2):188-90
Genomic testing: the clinical laboratory perspectiveExternal Web Site Icon
Faruki H Clin Pharmacol Ther 2013 Aug;94(2):190-2
Educational challenges in implementing genomic medicineExternal Web Site Icon
Passamani E Clin Pharmacol Ther 2013 Aug;94(2):192-5
Challenges in the pharmacogenomic annotation of whole genomesExternal Web Site Icon
R B Altman, et al. Clinical Pharmacology & Therapeutics (2013); 94 2, 211–213
A health-care system perspective on implementing genomic medicine: Pediatric acute lymphoblastic leukemia as a paradigmExternal Web Site Icon
Evans WE, et al. Clin Pharmacol Ther 2013 Aug;94(2):224-9

Clin Pharmacol Ther. 2013 Aug;94(2):169-72. doi: 10.1038/clpt.2013.101.

Genomic Medicine, Precision Medicine, Personalized Medicine: What's in a Name?

Source

Department of Medicine and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

Abstract

This issue of Clinical Pharmacology & Therapeutics is devoted to genomic medicine, and a reader may reasonably ask what we mean when we use those words. In the initial issue of the journal Genomics in 1987, McKusick and Ruddle pointed out that the descriptor "genome" had been coined in 1920 as a hybrid of "gene" and "chromosome," and that their new journal would focus on the "newly-developing discipline of mapping/sequencing (including analysis of the information)." A key milestone in the field was the generation of the first draft of a human genome in 2000, but this success really represents only one of many milestones in the journey from Mendel to MiSeq.
PMID:
23872826
[PubMed - in process]

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