Genomic Medicine, Precision Medicine, Personalized Medicine: What's in a Name?
Genomic medicine, precision medicine, personalized medicine: What's in a name?
Roden DM & Tyndale RF Clin Pharmacol Ther 2013 Aug;94(2):169-72
The opportunities and challenges of implementing genomics-informed personalized medicine
Chisholm RL Clin Pharmacol Ther 2013 Aug;94(2):181-2
CYP2D6 genotype should not be used to determine endocrine therapy in postmenopausal breast cancer patients
Rae JM Clin Pharmacol Ther 2013 Aug;94(2):183-5
CYP2D6 genotype and tamoxifen cctivity: Understanding interstudy variability in methodological quality
Ratain MJ, et al. Clin Pharmacol Ther 2013 Aug;94(2):185-7
Genomic medicine: too great expectations?
O'Rourke PP Clin Pharmacol Ther 2013 Aug;94(2):188-90
Genomic testing: the clinical laboratory perspective
Faruki H Clin Pharmacol Ther 2013 Aug;94(2):190-2
Educational challenges in implementing genomic medicine
Passamani E Clin Pharmacol Ther 2013 Aug;94(2):192-5
Challenges in the pharmacogenomic annotation of whole genomes
R B Altman, et al. Clinical Pharmacology & Therapeutics (2013); 94 2, 211–213
A health-care system perspective on implementing genomic medicine: Pediatric acute lymphoblastic leukemia as a paradigm
Evans WE, et al. Clin Pharmacol Ther 2013 Aug;94(2):224-9
Clin Pharmacol Ther. 2013 Aug;94(2):169-72. doi: 10.1038/clpt.2013.101.
Genomic Medicine, Precision Medicine, Personalized Medicine: What's in a Name?
Source
Department of Medicine and Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.Abstract
This issue of Clinical Pharmacology & Therapeutics is devoted to genomic medicine, and a reader may reasonably ask what we mean when we use those words. In the initial issue of the journal Genomics in 1987, McKusick and Ruddle pointed out that the descriptor "genome" had been coined in 1920 as a hybrid of "gene" and "chromosome," and that their new journal would focus on the "newly-developing discipline of mapping/sequencing (including analysis of the information)." A key milestone in the field was the generation of the first draft of a human genome in 2000, but this success really represents only one of many milestones in the journey from Mendel to MiSeq.
- PMID:
- 23872826
- [PubMed - in process]
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