Pharmacologic and Mechanical Prophylaxis of Venous Thromboembolism Among Special Populations - Research Review - Final | AHRQ Effective Health Care Program
More Research Needed to Effectively Prevent Blood Clots in Special Populations
There is a lack of high-quality evidence on the comparative effectiveness and safety of techniques to prevent venous thromboembolism (VTE) in special populations, including patients hospitalized with trauma, traumatic brain injury, burns, or liver disease; those on antiplatelet therapy; and those who are obese or underweight, according to a new review from AHRQ’s Effective Health Care Program. VTE affects an estimated 900,000 Americans every year, resulting in significant morbidity and mortality. Given that clinical trials typically exclude or do not report on these populations, more high-quality observational research on VTE prevention in special populations is needed and such research should control for confounding variables, such as provider and practice patterns and disease severity. These findings can be found in the full research review, Pharmacologic and Mechanical Prophylaxis of Venous Thromboembolism Among Special Populations.