domingo, 30 de junio de 2013

Babesia microti Infection, Eastern Pennsylvania, USA - Vol. 19 No. 7 - July 2013 - Emerging Infectious Disease journal - CDC

Babesia microti Infection, Eastern Pennsylvania, USA - Vol. 19 No. 7 - July 2013 - Emerging Infectious Disease journal - CDC

About the Cover

Summer Buzz

Polyxeni PotterComments to Author
Author affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Suggested citation for this article
Charles E. Burchfield (1893–1967) The Insect Chorus (1917) Opaque and transparent watercolor with ink, graphite, and crayon on off-white paper (50.8 cm × 38.1 cm) Munson-Williams-Proctor Arts Institute, Museum of Art, Utica, New York, Edward W. Root Bequest, 1957

Volume 19, Number 7—July 2013


Babesia microti Infection, Eastern Pennsylvania, USA

Marcela E. Perez AcostaComments to Author , Peter T. Ender, Erin M. Smith, and Jeffrey A. Jahre
Author affiliations: St. Luke’s University Hospital and Health Network, Bethlehem, Pennsylvania, USA
Suggested citation for this article


Infection with Babesia microti has not been well-described in eastern Pennsylvania, USA, despite the vector of this organism being prevalent. We report 3 cases of babesiosis in eastern Pennsylvania in persons without recent travel outside the region or history of blood transfusions, suggesting emergence of this infection.
Babesiosis is an intraerythrocytic infection caused by protozoan parasites of the genus Babesia. In the United States, Babesia microti is the most common species that causes human babesiosis. Disease-endemic areas include specific regions in the northeast and upper Midwest United States. Infection with this organism can be asymptomatic to life-threatening. Signs and symptoms include high fever, diaphoresis, chills, headaches, and anorexia. Patients can also have hemolytic anemia and thrombocytopenia (1).
B. microti is transmitted by the Ixodes scapularis tick, which is also the vector of Borrelia burgdorferi and Anaplasma phagocytophilum (2). Although B. burgdorferi is endemic to Pennsylvania (3), B. microti is not considered endemic to this region (4,5). We report 3 cases of human babesiosis in patients from Northampton County in eastern Pennsylvania, USA, who had not recently traveled outside the region or had blood transfusions. None of the patients had risk factors for severe babesiosis, such as asplenia.

The Patients

Patient 1 was a 68-year-old man who was hospitalized on August 18, 2011, because of 6 days of fever, arthralgias, generalized weakness, and confusion. He was given doxycycline for treatment of presumptive Lyme disease but showed no improvement. He had not traveled outside eastern Pennsylvania for >3 years. He had never received any blood transfusions. Although he did not recall any tick attachments, he enjoyed gardening and other outdoor activities.

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