domingo, 30 de junio de 2013

Etymologia: Verona Integron - Vol. 19 No. 7 - July 2013 - Emerging Infectious Disease journal - CDC

Etymologia: Verona Integron - Vol. 19 No. 7 - July 2013 - Emerging Infectious Disease journal - CDC

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Polyxeni PotterComments to Author
Author affiliation: Centers for Disease Control and Prevention, Atlanta, Georgia, USA
Suggested citation for this article
Charles E. Burchfield (1893–1967) The Insect Chorus (1917) Opaque and transparent watercolor with ink, graphite, and crayon on off-white paper (50.8 cm × 38.1 cm) Munson-Williams-Proctor Arts Institute, Museum of Art, Utica, New York, Edward W. Root Bequest, 1957

Volume 19, Number 7—July 2013

Etymologia

Etymologia: Verona Integron

Suggested citation for this article
Verona Integron
From the Latin integrare (to make whole), integrons are systems for capturing and spreading antibiotic resistance genes among gram-negative bacteria. Integrons were first described by Stokes and Hall in 1989, although they clearly contributed to the first outbreaks of multidrug resistance in the 1950s. The Verona integron was first described in carbapenem-resistant Pseudomonas aeruginosa isolated from a patient hospitalized at Verona University Hospital, Verona, Italy. Integrons are ancient structures that have been present in bacteria for millions of years, indicating that bacteria had the means of acquiring and disseminating antibiotic resistance long before humans developed antibiotics.

References

  1. Lauretti L, Riccio ML, Mazzariol A, Cornaglia G, Amicosante G, Fontana R, Cloning and characterization of blaVIM, a new integron-borne metallo-β-lactamase gene from a Pseudomonas aeruginosa clinical isolate. Antimicrob Agents Chemother. 1999;43:158490 .PubMedExternal Web Site Icon
  2. Mazel D. Integrons: agents of bacterial evolution. Nat Rev Microbiol. 2006;4:60820 . DOIExternal Web Site IconPubMedExternal Web Site Icon
  3. Stokes HW, Hall RM. A novel family of potentially mobile DNA elements encoding site-specific gene-integration functions: integrons. Mol Microbiol. 1989;3:166983 . DOIExternal Web Site IconPubMedExternal Web Site Icon
Suggested citation for this article: Etymologia: Verona integron. Emerg Infect Dis [serial on the Internet]. 2013 Jul [date cited]. http://dx.doi.org/10.3201/eid1907.ET1907External Web Site Icon
DOI: 10.3201/eid1907.ET1907

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