Creutzfeldt-Jakob Disease

Creutzfeldt-Jakob Disease

• CDC information: Classic Creutzfeldt-Jakob Disease
• CDC information: Variant Creutzfeldt-Jakob Disease
• National Institute of Neurological Disorders and Stroke:  About 5 to 10 percent of cases in the United States are hereditary.  In hereditary Creutzfeldt-Jakob Disease , the person has a family history of the disease and/or tests positive for a genetic mutation associated with disease
• 15 genes have been reported with Creutzfeldt-Jakob Disease, including 2 genomewide association studies/ The most known gene is the prion protein PRNP. To find out more, visit the HuGE Navigator
• Genetic variation in prion protein PRNP has been associated with several human diseases. To find out more, visit the HuGENavigator