Genomics|Resources|Video on familial hypercholesterolemia

Genomics|Resources|Video on familial hypercholesterolemia

Genomic Resources

Podcasts

CDC Podcast on Familial Hypercholesterolemia

On September 20th, 2010, CDC’s Office of Public Health Genomics (OPHG) released a podcast about the benefits of cascade screening to identify familial hypercholesterolemia, a common genetic disorder that causes high levels of low-density lipoprotein (or LDL) cholesterol that are present from birth. In the podcast, Renée M. Ned, PhD, MMSc, health scientist from OPHG, explains that:

• early detection and treatment of familial hypercholesterolemia has tremendous potential to prevent the onset of, and death related to, coronary heart disease;

• physicians should encourage patients to document their family health history, and make sure to collect and continually monitor this information;

• once a patient with FH is identified, physicians should use cascade testing to enable the early detection and treatment of affected relatives.

This podcast is part of CDC's Expert Commentary Series on Medscape.

Read the transcript.

Web Resources

National Institute for Health and Clinical Excellence (NICE). Identification and management of familial hypercholesterolaemia. NICE clinical guideline CG71. Issued August 2008.

• Familial hypercholesterolaemia (CG71)
• Make Early Diagnosis to Prevent Early Death (MEDPED)
• Online Mendelian Inheritance in Man (OMIM)-- Hypercholesterolemia, Autosomal Dominant
• World Health Organization (WHO). 1999. Familial Hypercholesterolaemia (FH): Report of a second WHO Consultation. Geneva. [PDF 2.45 MB]