Drug-Resistant Pandemic (H1N1) 2009, South Korea | CDC EID

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Volume 17, Number 4–April 2011
Dispatch
Drug-Resistant Pandemic (H1N1) 2009, South Korea1
Soo Youn Shin, Chun Kang, Jin Gwack, Joon Hyung Kim, Hyun Su Kim, Young A Kang, Ha Gyung Lee, Jin Seok Kim, Jong-Koo Lee, and Sung-Han Kim

Author affiliations: Korea Centers for Disease Control and Prevention, Seoul, South Korea (S.Y. Shin, C. Kang, J. Gwack, J.H. Kim, H.S. Kim, Y.A. Kang, H.G. Lee, J.S. Kim, J.-K. Lee); and University of Ulsan College of Medicine, Seoul (S.-H. Kim)
Suggested citation for this article

Abstract
Eleven patients with drug-resistant pandemic (H1N1) 2009 were identified in South Korea during May 2009–January 2010. Virus isolates from all patients had the H275Y mutation in the neuraminidase gene. One isolate had the I117M mutation. Of the 11 patients, 6 were <59 months of age, and 5 had underlying immunosuppressive conditions.

The Korea Centers for Disease Control and Prevention asked clinicians to report all patients with suspected cases of drug-resistant pandemic (H1N1) 2009 when these patients showed treatment failure for oseltamivir or had unusually prolonged viral shedding (defined as >5 days after the onset of symptoms) (1). We report nationwide surveillance data on the epidemiologic and clinical characteristics of patients infected with pandemic (H1N1) 2009 in South Korea.

full-text:
Drug-Resistant Pandemic (H1N1) 2009, South Korea | CDC EID


Suggested Citation for this Article
Shin SY, Kang C, Gwack J, Kim JH, Kim HS, Kang YA, et al. Drug-resistant pandemic (H1N1) 2009, South Korea. Emerg Infect Dis [serial on the Internet]. 2011 Apr [date cited].
http://www.cdc.gov/EID/content/17/4/702.htm


DOI: 10.3201/eid1704.101467



1Presented in part at the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy; 2010 Sep 12–15; Boston, Massachusetts, USA (late-breaker posters session, abstract V-448c).


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Sung-Han Kim, Department of Infectious Diseases, Asan Medical Center, University of Ulsan College of Medicine, 388–1 Pungnap-dong, Songpa-gu, Seoul, South Korea; email: kimsunghanmd@hotmail.com