Cystic Fibrosis Carrier Screening in Obstetric Cli... [Genet Test Mol Biomarkers. 2011] - PubMed result

Genet Test Mol Biomarkers. 2011 Mar 31. [Epub ahead of print]

Cystic Fibrosis Carrier Screening in Obstetric Clinical Practice: Knowledge, Practices, and Barriers, a Decade After Publication of Screening Guidelines.
Darcy D, Tian L, Taylor J, Schrijver I.

1 Master's Program in Human Genetics and Genetic Counseling, Department of Genetics, Stanford University School of Medicine , Palo Alto, California.

Abstract
Purpose: Cystic fibrosis (CF) carrier screening guidelines have been in place for almost a decade. The purpose of this study was to determine the current awareness by obstetricians of the existence and content of practice guidelines, the variety in practice regarding CF carrier screening, and the level of knowledge regarding CF genetics and screening result interpretation. We also explored potential barriers to offering screening and whether academic affiliation or type of practice influenced outcome. Methods: An online survey program was used to deliver a questionnaire to obstetricians throughout the United States. One hundred four respondents participated, with 143 answering all questions in the survey. Results: Although most obstetricians are aware of screening guidelines and have accurate knowledge about CF carrier screening, 12.3% were not aware of carrier screening guidelines, 17.7% were unable to interpret basic results, 16.5% experienced barriers to offering screening, and 43% lacked information regarding carrier rates, screening sensitivity, and residual risk. Conclusion: Most obstetricians offer CF carrier screening and will refer to genetic counseling services at times. However, we identified a deficiency of information in a concerning percentage of practitioners. This deficiency could be improved by targeted and readily accessible educational efforts, especially for obstetricians not affiliated with academia.

PMID: 21453058 [PubMed - as supplied by publisher]

Cystic Fibrosis Carrier Screening in Obstetric Cli... [Genet Test Mol Biomarkers. 2011] - PubMed result