martes, 17 de octubre de 2023
lunes, 16 de octubre de 2023
Women, power, and cancer: a Lancet Commission Monday, November 13, 2023
https://event.on24.com/wcc/r/4254417/AB192BBF49789E49D22AF74ED0F8551F?partnerref=tlcom_lancetwebinarshub_lancetwomenpowercancer23
Women, power, and cancer: a Lancet Commission
Nov 13, 2023
14:00 GMT / 9:00 EST
Women, power, and cancer: a Lancet Commission was created to address urgent questions at the intersection of social inequality, cancer risk and outcomes, and the status of women in society. In this Lancet Webinar, authors of The Lancet Commission will summarise the key findings of the Commission, including cancer equity and gender transformative policies, cancer prevention in women, gender-responsive frameworks in the healthcare context, and the value of women in cancer economics.
Directing vaccines to dendritic cells
Directing vaccines to dendritic cells
Many cancer vaccines under investigation use mRNA to deliver key information to the immune system. But most of these trials do not effectively target dendritic cells, a key orchestrator of the immune response. Because dendritic cells display antigens on their surface, which activates other components of the immune system and sounds the alarm about a potential threat, they are an attractive target for cancer treatment strategies.
With the ultimate goal of developing an improved vaccine strategy, a research team at Johns Hopkins University has designed a targeted, biodegradable nanoparticle that specifically delivers mRNA to dendritic cells. When evaluated in multiple mouse tumor models, treatment with the nanoparticles provided robust antitumor activity when combined with a type of therapy called immune checkpoint blockade. Their results were recently reported in the journal PNAS.
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