Engineered probiotic bacteria boost immune attack against pancreatic cancer

https://www.news-medical.net/news/20260724/Engineered-probiotic-bacteria-boost-immune-attack-against-pancreatic-cancer.aspx Cancer immunotherapies have transformed treatment for many cancers, but pancreatic cancer remains especially difficult to treat. One major reason is that pancreatic tumors often create a "cold" tumor microenvironment, where the tumor prevents immune cells from mounting a strong attack.

Evidence shows artificial sweeteners cannot be judged as a single group

https://www.news-medical.net/news/20260723/Evidence-shows-artificial-sweeteners-cannot-be-judged-as-a-single-group.aspx A review of seven sweeteners and mixed exposures shows why dose, formulation, diet, and individual biology matter when interpreting their potential effects on the gut and metabolism. A recent narrative review in the journal Nutrients synthesized the effects of seven individual non-nutritive artificial sweeteners (NASs) and mixed NAS exposures on gut microbiota composition and host metabolic health and developed an interactive knowledge graph to organize and navigate the available evidence.

Our twenty-five year journey The Lancet Infectious Diseases +...

Our twenty-five year journey The Lancet Infectious Diseases https://www.thelancet.com/journals/laninf/issue/vol26no8/PIIS1473-3099(26)X2007-2

Navigating Advances in TRK Fusion-Positive Cancers: A Collaborative Journey From Testing to Therapy Authors: David S. Hong, MD; Theodore W. Laetsch, MD; Jonathan C. Trent, MD, PhD

https://www.medscape.org/viewarticle/navigating-advances-trk-fusion-positive-cancers-2025a1000z5i?page=1&src=mkmcmr_driv_stan_mscpedu_260725-OUS-HONC-navigating-advances-trk-fusion-positive-cancers-2025a1000z5i-cta&uac=148436CN

2025 Winter Conference Update: Novel and Emerging Treatment Strategies for Breast Cancer Authors: François-Clément Bidard, MD, PhD; Mothaffar F. Rimawi, MD, FACP; Nadia Harbeck, MD, PhD

https://www.medscape.org/viewarticle/winter-conference-update-novel-and-emerging-treatment-2026a100030r?page=1&uac=148436CN&src=mkmcmr_driv_stan_mscpedu_260725-OUS-HONC-winter-conference-update-novel-and-emerging-treatment-2026a100030r-cta

GLP-1/GIP agonists and cancer: mechanisms, evidence, and nutrition implications Sedat Arslan* [1] , Ayca Aydin [2] + +...

https://www.academia.edu/2998-7741/3/2/10.20935/AcadOnco8234 Obesity and diabetes increase cancer risk through insulin resistance, chronic inflammation, and altered growth signaling. Glucagon-like peptide-1 (GLP-1) receptor agonists and dual GLP-1/glucose-dependent insulinotropic polypeptide (GIP) agonists reshape this metabolic milieu and are increasingly used for weight loss and glycemic control. Uncertainty persists about whether these agents influence cancer incidence or progression, and there is no consensus on nutrition care during therapy. We present a narrative, mechanism-to-clinic review that synthesizes randomized and observational human studies alongside translational evidence on insulin/IGF-1 pathways, adipokines, bile acids, and the microbiota. We also integrate practice-focused guidance on preserving lean mass, monitoring micronutrients, and managing gastrointestinal tolerance while on these agents. Current human evidence does not show a consistent increase in overall cancer risk with these therapies; however, signals are heterogeneous across tumor sites and follow-up remains limited. Randomized trials rarely adjudicate cancer outcomes, and pharmacovigilance and preclinical results are mixed and context-dependent. Weight loss and improved insulin sensitivity plausibly reduce pro-tumorigenic signaling, whereas rapid weight reduction may threaten muscle mass unless accompanied by proactive nutrition support and resistance exercise. Available data suggest no uniform carcinogenic signal from GLP-1/GIP therapies to date, but organ-specific effects and long-term safety require rigorous, adequately powered follow-up. Dietitians and oncology teams should co-manage patients using high-quality protein distributed across meals, fiber-rich, low-glycemic dietary patterns (such as Mediterranean-style eating), resistance exercise, and targeted micronutrient monitoring, alongside standardized recording of cancer-relevant outcomes. https://www.academia.edu/journals/academia-oncology/articles?source=journal-top-nav

Highlights From the Annual Neuro-Oncology Conference: Redefining IDH-Mutant Glioma Management Authors: Evanthia Galanis, MD; Shawn Hervey-Jumper, MD; Katherine B. Peters, MD, PhD, FAAN; Matthias Preusser, MD

https://www.medscape.org/viewarticle/1003198?src=mkmcmr_driv_stan_mscpedu_260725-OUS-HONC-1003198-cta&uac=148436CN

Current and Future Oral SERD Strategies in the Management of ER-Positive/HER2-Negative MBC: Analyzing the Clinical Data Authors: Komal Jhaveri, MD, FACP, FASCO; Shaheenah Dawood, MD, MPH

https://www.medscape.org/viewarticle/current-and-future-oral-serd-strategies-management-er-2026a100022b?page=1&src=mkmcmr_driv_stan_mscpedu_260726-OUS-HONC-current-and-future-oral-serd-strategies-management-er-2026a100022b-cta&uac=148436CN

Are Smart Glasses the Future of Collaborative Surgery? Nelly Abulata, MD, PhD, MBA; Amgad Nakhla, MBBCh, PhD + +++++

https://www.medscape.com/viewarticle/are-smart-glasses-future-collaborative-surgery-2026a1000obf?ecd=mkm_ret_260726_mscpmrk-OUS_ExcNews_etid8527949&uac=148436CN&impID=8527949 More Digital Health Pulse Content From This Year Health Data: Who Owns It, Who Profits, Who Protects It? https://www.medscape.com/viewarticle/data-new-blood-test-who-owns-it-who-profits-who-protects-it-2026a1000l7l?ecd=mkm_ret_260726_mscpmrk-OUS_ExcNews_etid8527949&uac=148436CN&impID=8527949 Inside OCT and IVUS: AI’s New Edge in PCI https://www.medscape.com/viewarticle/inside-oct-and-ivus-ais-new-edge-pci-2026a1000fkf?ecd=mkm_ret_260726_mscpmrk-OUS_ExcNews_etid8527949&uac=148436CN&impID=8527949 Can AI Fix the Mental Health Crisis? https://www.medscape.com/viewarticle/can-ai-fix-mental-health-crisis-2026a1000bcn?ecd=mkm_ret_260726_mscpmrk-OUS_ExcNews_etid8527949&uac=148436CN&impID=8527949 Want Digital Care That Works? Start With These Questions https://www.medscape.com/viewarticle/want-digital-care-works-start-these-questions-2026a10007oe?ecd=mkm_ret_260726_mscpmrk-OUS_ExcNews_etid8527949&uac=148436CN&impID=8527949 Clinical Practice, Digital Fluency: The Hybrid-Role Era https://www.medscape.com/viewarticle/clinical-practice-digital-fluency-hybrid-role-era-2026a10005m4?ecd=mkm_ret_260726_mscpmrk-OUS_ExcNews_etid8527949&uac=148436CN&impID=8527949

Clinical Perspectives on the Use of PI3K/AKT Pathway Inhibitors in the Management of HR+/HER2− Metastatic Breast Cancer Authors: Peter Schmid, MD, PhD, FRCP; Kevin Kalinsky, MD, MS, FASCO; Frédérique Penault-Llorca, MD, PhD

https://www.medscape.org/viewarticle/clinical-perspectives-use-pi3k-akt-pathway-inhibitors-2026a100087h?page=1&src=mkmcmr_driv_stan_mscpedu_260726-OUS-HONC-clinical-perspectives-use-pi3k-akt-pathway-inhibitors-2026a100087h-cta&uac=148436CN

Winter Break for the "Equitable Health" Blog Group... the blogs will not be updated on July 26, 27, 28, 29, and 30, 2026... We apologize for this, but we hope you understand that we deserve a break... We will return on July 31, God willing... Many thanks to all our readers and followers (whose numbers are constantly growing)... Until then... The Editor...

Receso Invernal del grupo de blog´s de "salud equitativa"... los días 26, 27, 28, 29, y 30 de julio de 2026, los blog´s no se actualizarán... pedimos disculpas por ello, pero esperamos sepan entender que merecemos un descanso... regresaremos el 31 de julio si Dios lo permite... muchas gracias a todos los lectores y seguidores (que cada vez son más)... hasta entonces... El editor... Grupo de blog´s de “salud equitativa”, cuyo titular es Víctor Norberto Cerasale Morteo, en Salta, Argentina… https://wwweldispreciau.blogspot.com/ https://eldispensador.blogspot.com/ https://saludequitativa.blogspot.com/ https://herenciageneticayenfermedad.blogspot.com/ https://elbiruniblogspotcom.blogspot.com/ Winter Break for the "Equitable Health" Blog Group... the blogs will not be updated on July 26, 27, 28, 29, and 30, 2026... We apologize for this, but we hope you understand that we deserve a break... We will return on July 31, God willing... Many thanks to all our readers and followers (whose numbers are constantly growing)... Until then... The Editor... "Equitable Health" Blog Group, owned by Víctor Norberto Cerasale Morteo, in Salta, Argentina... https://wwweldispreciau.blogspot.com/ https://eldispensador.blogspot.com/ https://saludequitativa.blogspot.com/ https://herenciageneticayenfermedad.blogspot.com/ https://elbiruniblogspotcom.blogspot.com/ Pause hivernale pour le groupe de blogs « Equitable Health »… Les articles ne seront pas mis à jour les 26, 27, 28, 29 et 30 juillet 2026… Nous vous prions de nous excuser pour ce désagrément, mais nous espérons que vous comprendrez que nous méritons bien une pause… Nous serons de retour le 31 juillet, si Dieu le veut… Un grand merci à tous nos lecteurs et abonnés (dont le nombre ne cesse de croître)… À bientôt… La rédaction… Le groupe de blogs « Equitable Health », propriété de Víctor Norberto Cerasale Morteo, à Salta, en Argentine… https://wwweldispreciau.blogspot.com/ https://eldispensador.blogspot.com/ https://saludequitativa.blogspot.com/ https://herenciageneticayenfermedad.blogspot.com/ https://elbiruniblogspotcom.blogspot.com/ Winterpause für die Bloggruppe „Gerechte Gesundheit“ … Die Blogs werden am 26., 27., 28., 29. und 30. Juli 2026 nicht aktualisiert. Wir bitten um Entschuldigung und hoffen auf Ihr Verständnis, dass wir uns eine Auszeit verdient haben. Wir sind am 31. Juli wieder für Sie da, so Gott will. Vielen Dank an alle unsere Leser und Follower (deren Zahl stetig wächst). Bis dahin … Die Redaktion der Bloggruppe „Gerechte Gesundheit“, Inhaber: Víctor Norberto Cerasale Morteo, Salta, Argentinien. https://wwweldispreciau.blogspot.com/ https://eldispensador.blogspot.com/ https://saludequitativa.blogspot.com/ https://herenciageneticayenfermedad.blogspot.com/ https://elbiruniblogspotcom.blogspot.com/ Зимний перерыв для блог-группы "Equitable Health"... блоги не будут обновляться 26, 27, 28, 29 и 30 июля 2026 года... Приносим свои извинения, но надеемся на ваше понимание, что мы заслужили перерыв... Мы вернемся 31 июля, если Бог даст... Большое спасибо всем нашим читателям и подписчикам (число которых постоянно растет)... До тех пор... Редактор... Блог-группа "Equitable Health", принадлежащая Виктору Норберто Серасале Мортео, Сальта, Аргентина... https://wwweldispreciau.blogspot.com/ https://eldispensador.blogspot.com/ https://saludequitativa.blogspot.com/ https://herenciageneticayenfermedad.blogspot.com/ https://elbiruniblogspotcom.blogspot.com/ "इक्विटेबल हेल्थ" ब्लॉग ग्रुप के लिए विंटर ब्रेक... ब्लॉग 26, 27, 28, 29, और 30 जुलाई, 2026 को अपडेट नहीं किए जाएंगे... हम इसके लिए माफ़ी चाहते हैं, लेकिन हमें उम्मीद है कि आप समझेंगे कि हम एक ब्रेक के हकदार हैं... हम 31 जुलाई को वापस आएंगे, भगवान चाहेंगे... हमारे सभी रीडर्स और फॉलोअर्स (जिनकी संख्या लगातार बढ़ रही है) का बहुत-बहुत धन्यवाद... तब तक... एडिटर... "इक्विटेबल हेल्थ" ब्लॉग ग्रुप, जिसके मालिक विक्टर नॉरबर्टो सेरासले मोर्टेओ हैं, साल्टा, अर्जेंटीना में है... https://wwweldispreciau.blogspot.com/ https://eldispensador.blogspot.com/ https://saludequitativa.blogspot.com/ https://herenciageneticayenfermedad.blogspot.com/ https://elbiruniblogspotcom.blogspot.com/ Recesso de Inverno para o Grupo de Blogs "Saúde Equitativa"... os blogs não serão actualizados nos dias 26, 27, 28, 29 e 30 de Julho de 2026... Pedimos desculpa por isso, mas esperamos que compreendam que merecemos uma pausa... Regressaremos no dia 31 de Julho, se Deus quiser... Muito obrigado a todos os nossos leitores e seguidores (cujo número está em constante crescimento)... Até lá... A Equipa Editorial... Grupo de Blogs "Saúde Equitativa", propriedade de Víctor Norberto Cerasale Morteo, em Salta, Argentina... https://wwweldispreciau.blogspot.com/ https://eldispensador.blogspot.com/ https://saludequitativa.blogspot.com/ https://herenciageneticayenfermedad.blogspot.com/ https://elbiruniblogspotcom.blogspot.com/ Pausa invernale per il gruppo di blog "Equitable Health"... i blog non verranno aggiornati il 26, 27, 28, 29 e 30 luglio 2026... Ci scusiamo per questo, ma speriamo che comprendiate che ci meritiamo una pausa... Torneremo il 31 luglio, a Dio piacendo... Un sentito ringraziamento a tutti i nostri lettori e follower (il cui numero è in costante crescita)... A presto... Il Direttore... Gruppo di blog "Equitable Health", di proprietà di Víctor Norberto Cerasale Morteo, a Salta, Argentina... https://wwweldispreciau.blogspot.com/ https://eldispensador.blogspot.com/ https://saludequitativa.blogspot.com/ https://herenciageneticayenfermedad.blogspot.com/ https://elbiruniblogspotcom.blogspot.com/ "ஈக்விடபிள் ஹெல்த்" வலைப்பதிவுக் குழுவிற்கு குளிர்கால இடைவேளை... ஜூலை 26, 27, 28, 29, மற்றும் 30, 2026 ஆகிய தேதிகளில் வலைப்பதிவுகள் புதுப்பிக்கப்படாது... இதற்காக வருந்துகிறோம், ஆனால் எங்களுக்கு ஒரு இடைவேளை தேவை என்பதை நீங்கள் புரிந்துகொள்வீர்கள் என்று நம்புகிறோம்... எல்லாம் வல்ல இறைவனின் அருளால், ஜூலை 31 அன்று நாங்கள் திரும்புவோம்... எங்கள் வாசகர்கள் மற்றும் பின்தொடர்பவர்கள் அனைவருக்கும் மிக்க நன்றி (அவர்களின் எண்ணிக்கை தொடர்ந்து அதிகரித்து வருகிறது)... அதுவரை... ஆசிரியர்... "ஈக்விடபிள் ஹெல்த்" வலைப்பதிவுக் குழு, விக்டர் நோர்பெர்டோ செராசேல் மோர்டியோவுக்குச் சொந்தமானது, சால்டா, அர்ஜென்டினா... https://wwweldispreciau.blogspot.com/ https://eldispensador.blogspot.com/ https://saludequitativa.blogspot.com/ https://herenciageneticayenfermedad.blogspot.com/ https://elbiruniblogspotcom.blogspot.com/ “公平健康”博客组冬季休刊……博客将于2026年7月26日、27日、28日、29日和30日暂停更新……对此我们深表歉意，但希望您能理解我们需要休息……我们将于7月31日恢复更新，如果一切顺利……非常感谢所有读者和关注者（人数还在不断增长）……此致……编辑……“公平健康”博客组，由阿根廷萨尔塔省的维克托·诺贝托·塞拉萨莱·莫特奥所有…… https://wwweldispreciau.blogspot.com/ https://eldispensador.blogspot.com/ https://saludequitativa.blogspot.com/ https://herenciageneticayenfermedad.blogspot.com/ https://elbiruniblogspotcom.blogspot.com/

Who owns cardiometabolic disease? The Lancet +... + +

Who owns cardiometabolic disease? The Lancet https://www.thelancet.com/journals/lancet/issue/vol408no10552/PIIS0140-6736(26)X2027-X Who owns cardiometabolic disease? The Lancet https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01497-2/fulltext?dgcid=raven_jbs_etoc_feature_lancet Towards precision medicine: electroconvulsive therapy as a treatment option in a rare disease Dr Jana de Villiers, FRCPsycha Send email to jana.devilliers@nhs.scot ∙ Prof Jennifer Mulle, PhDb ∙ Sujatha Maiya, MRCPsychc ∙ Adannaya Igwe, MBBChir https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)00694-X/abstract?dgcid=raven_jbs_etoc_feature_lancet

Naming disease, shaping care: patient perspectives matter eClinicalMedicine ++... +

Naming disease, shaping care: patient perspectives matter eClinicalMedicine https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(26)00378-0/fulltext?dgcid=raven_jbs_etoc_email Jul 2026 Volume 97 https://www.thelancet.com/journals/eclinm/issue/vol97nonull/PIIS2589-5370(26)X2007-7 Challenges and possible solutions towards reaching global cervical cancer elimination Laila Sara Arroyo Mühr ∙ Joakim Dillner https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(26)00138-0/fulltext?dgcid=raven_jbs_etoc_feature_eclinm

Managing Endometrial Cancer: Unpacking the Data Behind the Latest Immunotherapy Advancements Authors: Ana Oaknin, MD, PhD; Domenica Lorusso, MD, PhD

https://www.medscape.org/viewarticle/managing-endometrial-cancer-unpacking-data-behind-latest-2026a1000bh0?page=1&uac=148436CN&src=mkmcmr_driv_cust_mscpedu_260723-OUS-HONC_NOLO-managing-endometrial-cancer-unpacking-data-behind-latest-2026a1000bh0-cta

Most Read Papers - Cancer Science & Oncogenesis +...

https://read.qxmd.com/collection/1133?ecd=wnl_readmost_260724

Future‑Ready Hematologists: Practical and Ethical Use of Artificial Intelligence (AI) in Hematology and Oncology Authors: Jakob N. Kather, MD, MSc; Chan Cheah, MBBS, DMSc; Matthew Lunning, DO, FACP

https://www.medscape.org/viewarticle/1003401?mkmcmr_driv_cust_mscpedu_260724-Global-HONC-1003401-cta&uac=148436CN

Beyond Intervals: The Next Era of Continuous Delivery in Retinal Medicine Authors: Margaret A Chang, MD, MS; Andrew A Chang, MBBS, PhD, FRANZCO; Santiago Abengoechea, MD

https://www.medscape.org/viewarticle/beyond-intervals-next-era-continuous-delivery-retinal-2026a1000mm4?page=1

Fast Five Quiz: How Much Do You Know About Colorectal Cancer? Reviewed by Tomislav Dragovich, MD, PhD; Karl J. D'Silva, MD

https://reference.medscape.com/viewarticle/fast-five-quiz-how-much-do-you-know-about-colorectal-cancer-2025a1000djz?_gl=1*1j1ojw7*_gcl_aw*R0NMLjE3ODM4NzAxMzguQ2p3S0NBanc5c3pTQmhCTkVpd0FDNTdTcTJZUXZTZkkxc01raEZQZ1VLSWRQZkVUdGU4U212WEI0NGh3aEE5WmMtVDhTSVBEWlBzNmdSb0NiT1FRQXZEX0J3RQ..*_gcl_au*NjkzMDY5MjIxLjE3ODA2NzA2MDAuNTQ3NDg3NzUwLjE3ODQ5ODcyMzAuMTc4NDk4Nzc4NS4yMDgwMTc0Mzk2LjE3ODQ5MDIyOTQuMTc4NDk4Nzc4NQ..

Drinking Water Contaminants Tied to Uterine Cancer Risk Megan Brooks July 24, 2026 JAMA Netw Open. 2026;9(7):e2624391. doi:10.1001/jamanetworkopen.2026.24391

https://www.medscape.com/viewarticle/drinking-water-contaminants-tied-uterine-cancer-risk-2026a1000p62?src= Women with relatively greater exposure to common disinfection byproducts in drinking water — even at levels below federal limits — may be at an increased risk for uterine cancer, a large prospective study suggests. Among over 53,000 California women followed for two decades, those exposed to the highest levels of disinfection byproducts called trihalomethanes (THMs) had an 18% higher risk for uterine cancer vs women with the lowest exposure levels. They also had a 23% higher risk for endometrioid tumors, specifically.

MRI-Based Staging Matches Digital Rectal Examination Accuracy in Prostate Cancer Survival Edited by Mamta Pawara

https://www.medscape.com/viewarticle/mri-based-staging-matches-digital-rectal-examination-2026a1000omm?src= Preoperative MRI-based T staging demonstrated oncologic risk discrimination comparable to traditional digital rectal examinations (DREs) for predicting survival outcomes in men with clinically localised or locally advanced prostate cancer (PCa) who underwent radical prostatectomy, a multicentre study found.